CLAYTON’S BASIC PHARMACOLOGY FOR
NURSES 19TH EDITION FINAL ASSESSMENT
TEST BANK 2026 EXTENSIVE QUESTIONS
AND PRECISE VERIFIED SOLUTIONS
GUARANTEED A+
⩥ classes of medication which account for the largest number of ADR's.
Answer: - antibiotics
- cardiovascular medicines
- cancer chemotherapy agents
- analgesics
- antiinflammatory agents
⩥ occurs when something unusual or abnormal happens when a drug is
first administered; generally a result of a patient's inability to metabolize
a drug because of genetic deficiency of certain enzymes. Answer:
idiosyncratic reaction
⩥ occurs after previous exposure to a medication, when re-exposed
antibodies cause a reaction; most commonly seen as hives which cause
severe itching. Answer: allergic/hypersensitivity reactions
⩥ severe itching is also called. Answer: uticaria
,⩥ severe or life threatening reaction to drug which a patient was
previously exposed to; causes respiratory distress and cardiovascular
colapse. Answer: anaphylactic reaction
⩥ occurs when the action of one drug is altered or changed by the action
of another drug. Answer: drug interaction
⩥ drug interactions are elicited in two ways:. Answer: - by agents that
when combined increase the actions of one or both drugs
- by agents that when combined decrease the effectiveness of one or both
drugs
⩥ the mechanisms of drug interactions can be categorized as those that
change the ___________________ of a drug and those that enhance the
____________________ effect of a drug. Answer: - ADME
- pharmacological
⩥ most drug interactions that change absorption take place in the.
Answer: GI tract (specifically the stomach)
⩥ drug interactions that cause a change in distribution usually affect the
____________________ of a drug to an inactive site. Answer: binding
, ⩥ if a drug is 90% bound to a protein, then ___% of the drug is proving
the physiologic effect. Answer: 10%
⩥ drug interactions usually result from a change in metabolism that
involves inhibiting or inducing (stimulating) the __________________
that metabolize a drug. Answer: enzymes
⩥ medicines known to bind to enzymes and to slow the metabolism of
other drugs include:. Answer: - verapamil
- cloramphenicol
- ketoconazole
- amiodarone
- cimetidine
- erythromycin
⩥ common drugs that bind to enzymes and increase the metabolism of
other drugs:. Answer: - phenobarbital
- carbamazepine
- rifampin
- phenytoin
⩥ when administered with enzyme inducers, the dosages of the more
rapidly metabolized drugs should generally be _______________ to
provide therapeutic activity. Answer: increased
NURSES 19TH EDITION FINAL ASSESSMENT
TEST BANK 2026 EXTENSIVE QUESTIONS
AND PRECISE VERIFIED SOLUTIONS
GUARANTEED A+
⩥ classes of medication which account for the largest number of ADR's.
Answer: - antibiotics
- cardiovascular medicines
- cancer chemotherapy agents
- analgesics
- antiinflammatory agents
⩥ occurs when something unusual or abnormal happens when a drug is
first administered; generally a result of a patient's inability to metabolize
a drug because of genetic deficiency of certain enzymes. Answer:
idiosyncratic reaction
⩥ occurs after previous exposure to a medication, when re-exposed
antibodies cause a reaction; most commonly seen as hives which cause
severe itching. Answer: allergic/hypersensitivity reactions
⩥ severe itching is also called. Answer: uticaria
,⩥ severe or life threatening reaction to drug which a patient was
previously exposed to; causes respiratory distress and cardiovascular
colapse. Answer: anaphylactic reaction
⩥ occurs when the action of one drug is altered or changed by the action
of another drug. Answer: drug interaction
⩥ drug interactions are elicited in two ways:. Answer: - by agents that
when combined increase the actions of one or both drugs
- by agents that when combined decrease the effectiveness of one or both
drugs
⩥ the mechanisms of drug interactions can be categorized as those that
change the ___________________ of a drug and those that enhance the
____________________ effect of a drug. Answer: - ADME
- pharmacological
⩥ most drug interactions that change absorption take place in the.
Answer: GI tract (specifically the stomach)
⩥ drug interactions that cause a change in distribution usually affect the
____________________ of a drug to an inactive site. Answer: binding
, ⩥ if a drug is 90% bound to a protein, then ___% of the drug is proving
the physiologic effect. Answer: 10%
⩥ drug interactions usually result from a change in metabolism that
involves inhibiting or inducing (stimulating) the __________________
that metabolize a drug. Answer: enzymes
⩥ medicines known to bind to enzymes and to slow the metabolism of
other drugs include:. Answer: - verapamil
- cloramphenicol
- ketoconazole
- amiodarone
- cimetidine
- erythromycin
⩥ common drugs that bind to enzymes and increase the metabolism of
other drugs:. Answer: - phenobarbital
- carbamazepine
- rifampin
- phenytoin
⩥ when administered with enzyme inducers, the dosages of the more
rapidly metabolized drugs should generally be _______________ to
provide therapeutic activity. Answer: increased
