APHON Principles of Chemo and Biotherapy
Exam || 2026 (Actual Exam) Questions with
verified Answers | FREQUENTLY MOST TESTED
QUESTIONS AND VERIFIED SOLUTIONS @ 2026
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Terms in this set (56)
Biotherapy Targeted anticancer agents also known as
biological response modifiers (BRM)
Tyrosine kinase inhibitors (TKIs) are Biotherapy
what class
Monoclonal antibodies (MoAbs) are Biotherapy
what class
Define pharmacokinetics Study of drug absorption, metabolism, and
excretion
Define pharmacodynamics The concentration of the drug in the body and how
it produces a response
Define adjuvant chemotherapy The use of chemo after another type of therapy,
such as surgery, to treat residual disease or
undetectable metastasis.
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, 3/18/26, 7:00 PM APHON Principles of Chemo and Biotherapy Exam || 2026 (Actual Exam) Questions with verified Answers | FREQUENTLY MOST …
Define neoadjuvant chemotherapy When chemo is used preoperatively to decrease
tumor burden in order to make it easier to remove
the tumor surgically.
Define sanctuary sites Sites within the body where tumor cells sequester
and are not easily reached by chemo such as the
CNS
What normal cells are most often Hematopoietic, mucosal (mouth & GI), hair follicles
effected by chemotherapy
Why use chemotherapy To prevent cancer cells from dividing,
metastasizing, and ultimately causing the death of
the patient
Cure To permanently eradicate the cancer
Control To extend the length & QOL when cure is not
feasible or realistic
Palliation Minimize pain and suffering during end of life
Resting phase of cell cycle Gap 0 - cells not dividing
Postmitotic phase Gap 1 - enzymes needed for DNA synthesis are
produced, protein and RNA synthesis takes place
(18 Hours)
Synthesis (S) Phase Cellular DNA duplicated (20 hours)
Premitotic phase Gap 2 - both protein and RNA synthesis occur,
precursors of mitotic spindle are produced.
Shortest phase
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