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,What is the therapeutic range on a log dose effect curve - Correct Answer: Where the dose is
increasing sharply
On a log dose effect curve where is the maximum response - Correct Answer: Where the curve
plateaus
What is potency - Correct Answer: The amount of a drug needed to produce an effect
What is efficacy - Correct Answer: The maximum effect that a drug can have regardless of the dose.
Once reached delivering more of the drug will not add effects
Efficacy and potency are unrelated. - Correct Answer: ...
Enteral drug administration is what - Correct Answer: Placed directly into GI tract. This is done by
taking the drug orally, rectally
What is parenteral administration of a drug - Correct Answer: Injection
What is the most cost effective and safest way to take a drug - Correct Answer: Orally
What can happen is a drug tHat is made from proteins is taken orally - Correct Answer: The acidity of
the GI tract can be inactivated. ex. Insulin can not be taken orally
What is the first pass effect - Correct Answer: When a drug passes through the hepatic portal
circulation. Some of the active ingredients can be inactivated.
This may decrease some of the available drugs that can be activated.
What happens when a drug has a high first pass effect. - Correct Answer: They require a larger dose.
, How are the phase one reactions carried out in the liver - Correct Answer: By microsomal or
cytochrome p450 enzymes
Alcohol tolerance is a common example
When would you want to administer a drug rectally - Correct Answer: When a person is unconscious
or vomiting
What are the different types of parenteral drug administrations - Correct Answer: Intra vascular
Intramuscular
Subcutaneous
Intradermal
Inhalation
Topical
What are some characteristics of the intra vascular parenteral route - Correct Answer: Absorption
phase is bypassed
Most rapid drug response
Drug is really hard to be retrieved
What are some characteristics of intramuscular route parenteral drug admin - Correct Answer:
Sustained effect
Usually delivered in the deltoid or gluteals
What are some characteristics of subcutaneous parenteral drug admin - Correct Answer: Best route to
admin protein products
May produce a sterile access or a hematoma
Insulin, anesthesia