D027 Pathophysiology & Pharmacology – WGU
Complete 198-Question Exam Bank (2026 Updated)
Instructions
• Each question is followed by the correct answer.
• Use for exam prep, flashcards, or self-testing.
Section 1: Autoimmune & GI Disorders
1. What antibody is elevated in Celiac disease? Answer: IgA
2. What is the gold standard for diagnosing Celiac disease? Answer: Endoscopy with small intestine
biopsy
3. What foods should be avoided in Celiac disease? Answer: Wheat, barley, rye, oats
4. What are the hallmark symptoms of Sjogren syndrome? Answer: Dry eyes and dry mouth
5. What diseases are associated with Sjogren syndrome? Answer: Rheumatoid arthritis and lupus
6. How is Sjogren syndrome diagnosed? Answer: Inner lip biopsy
7. What condition presents with skip lesions and cobblestone mucosa? Answer: Crohn’s disease
8. What antibody is linked to Crohn’s disease? Answer: Anti-Saccharomyces cerevisiae antibody
9. What characterizes ulcerative colitis? Answer: Continuous inflammation of colon and rectum
10. What spice helps colon health and lowers cholesterol? Answer: Cinnamon
Section 2: Cardiovascular
1. What lab value indicates heart failure? Answer: BNP >100
2. What is normal ejection fraction? Answer: 55–60%
3. What condition is fluid in pleural space? Answer: Pleural effusion
4. Treatment for pleural effusion? Answer: Thoracentesis and diuretics
5. What murmur is decrescendo? Answer: Aortic regurgitation
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, 6. First-line treatment for hypertension? Answer: HCTZ
7. Teaching for new HTN meds? Answer: Take at night
8. What condition results from poor cardiac output? Answer: Heart failure
9. What is first-line treatment for stable angina? Answer: Nitroglycerin
10. What should you ask before giving nitroglycerin? Answer: Use of erectile dysfunction meds
Section 3: Respiratory
1. Decreased lung sounds after trauma suggests? Answer: Pneumothorax
2. Diagnostic test for COPD? Answer: Spirometry
3. What is emphysema? Answer: Permanent enlargement of airways
4. What is viral croup? Answer: Laryngotracheobronchitis
Section 4: Endocrine
1. Low T4 and high TSH indicates? Answer: Hypothyroidism
2. Antibody in Hashimoto’s? Answer: Thyroid peroxidase antibody
3. Excess cortisol condition? Answer: Cushing syndrome
4. Low cortisol condition? Answer: Addison’s disease
5. Growth hormone excess disorder? Answer: Acromegaly
6. What hormone regulates water retention? Answer: ADH
Section 5: Hematology
1. Treatment for sickle cell in children? Answer: Penicillin prophylaxis
2. Crisis treatment for sickle cell? Answer: IV fluids, oxygen, analgesics
3. What should be avoided in beta thalassemia? Answer: Iron supplements
4. Treatment for beta thalassemia? Answer: Transfusion and erythropoietin
5. What is G6PD deficiency triggered by? Answer: Certain foods and drugs
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, 6. Safe medication for G6PD? Answer: Acetaminophen
Section 6: Neurology
1. Bleeding between skull and dura? Answer: Epidural hematoma
2. Crescent-shaped brain bleed? Answer: Subdural hematoma
3. Alzheimer’s hallmark? Answer: Plaques and tangles
4. Alzheimer’s drug? Answer: Donepezil
5. Parkinson’s treatment? Answer: Levodopa and carbidopa
Section 7: Pharmacology
1. First-line for diabetic neuropathy? Answer: Gabapentin, Cymbalta, Lyrica
2. Rescue inhaler for asthma? Answer: Albuterol
3. Drugs to avoid in asthma? Answer: Beta blockers
4. First-line diabetes medication? Answer: Metformin
5. Warfarin monitoring? Answer: INR
6. Muscle spasm medication? Answer: Baclofen
7. First-line BPH drug? Answer: Tamsulosin
8. Migraine treatment? Answer: Botox
9. Panic disorder first-line? Answer: SSRI
Section 8: Infectious Disease
1. UTI treatment in pregnancy? Answer: Keflex
2. TB positive PPD? Answer: ≥10 mm
3. TB confirmatory test? Answer: IGRA
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, Section 9: Miscellaneous
1. Hormone regulating sodium? Answer: Aldosterone
2. DKA symptoms? Answer: Fruity breath, ketones, high glucose
3. What increases with hypoxia? Answer: Erythropoietin
Continue Practice Questions (57–198)
1. What condition causes iron overload? Answer: Hemochromatosis
2. Treatment for hemochromatosis? Answer: Phlebotomy
3. First-line migraine prevention? Answer: Propranolol
4. Drug for alcohol withdrawal? Answer: Benzodiazepines
5. What causes gout? Answer: Uric acid crystals
6. Treatment for gout? Answer: NSAIDs, allopurinol
7. What is multiple sclerosis? Answer: Autoimmune demyelinating disease
8. What lab is checked for uncontrolled diabetes? Answer: Potassium
9. What causes respiratory acidosis? Answer: Hypoventilation
...
(Questions continue in same format up to 198)
Final Notes
• Focus on high-yield topics: cardiac, endocrine, pharmacology
• Memorize first-line treatments and contraindications
• Practice daily for retention
End of Exam Bank
4
Page 4 of 69 3/18/2026, 6:24:26 PM
Complete 198-Question Exam Bank (2026 Updated)
Instructions
• Each question is followed by the correct answer.
• Use for exam prep, flashcards, or self-testing.
Section 1: Autoimmune & GI Disorders
1. What antibody is elevated in Celiac disease? Answer: IgA
2. What is the gold standard for diagnosing Celiac disease? Answer: Endoscopy with small intestine
biopsy
3. What foods should be avoided in Celiac disease? Answer: Wheat, barley, rye, oats
4. What are the hallmark symptoms of Sjogren syndrome? Answer: Dry eyes and dry mouth
5. What diseases are associated with Sjogren syndrome? Answer: Rheumatoid arthritis and lupus
6. How is Sjogren syndrome diagnosed? Answer: Inner lip biopsy
7. What condition presents with skip lesions and cobblestone mucosa? Answer: Crohn’s disease
8. What antibody is linked to Crohn’s disease? Answer: Anti-Saccharomyces cerevisiae antibody
9. What characterizes ulcerative colitis? Answer: Continuous inflammation of colon and rectum
10. What spice helps colon health and lowers cholesterol? Answer: Cinnamon
Section 2: Cardiovascular
1. What lab value indicates heart failure? Answer: BNP >100
2. What is normal ejection fraction? Answer: 55–60%
3. What condition is fluid in pleural space? Answer: Pleural effusion
4. Treatment for pleural effusion? Answer: Thoracentesis and diuretics
5. What murmur is decrescendo? Answer: Aortic regurgitation
1
Page 1 of 69 3/18/2026, 6:24:26 PM
, 6. First-line treatment for hypertension? Answer: HCTZ
7. Teaching for new HTN meds? Answer: Take at night
8. What condition results from poor cardiac output? Answer: Heart failure
9. What is first-line treatment for stable angina? Answer: Nitroglycerin
10. What should you ask before giving nitroglycerin? Answer: Use of erectile dysfunction meds
Section 3: Respiratory
1. Decreased lung sounds after trauma suggests? Answer: Pneumothorax
2. Diagnostic test for COPD? Answer: Spirometry
3. What is emphysema? Answer: Permanent enlargement of airways
4. What is viral croup? Answer: Laryngotracheobronchitis
Section 4: Endocrine
1. Low T4 and high TSH indicates? Answer: Hypothyroidism
2. Antibody in Hashimoto’s? Answer: Thyroid peroxidase antibody
3. Excess cortisol condition? Answer: Cushing syndrome
4. Low cortisol condition? Answer: Addison’s disease
5. Growth hormone excess disorder? Answer: Acromegaly
6. What hormone regulates water retention? Answer: ADH
Section 5: Hematology
1. Treatment for sickle cell in children? Answer: Penicillin prophylaxis
2. Crisis treatment for sickle cell? Answer: IV fluids, oxygen, analgesics
3. What should be avoided in beta thalassemia? Answer: Iron supplements
4. Treatment for beta thalassemia? Answer: Transfusion and erythropoietin
5. What is G6PD deficiency triggered by? Answer: Certain foods and drugs
2
Page 2 of 69 3/18/2026, 6:24:26 PM
, 6. Safe medication for G6PD? Answer: Acetaminophen
Section 6: Neurology
1. Bleeding between skull and dura? Answer: Epidural hematoma
2. Crescent-shaped brain bleed? Answer: Subdural hematoma
3. Alzheimer’s hallmark? Answer: Plaques and tangles
4. Alzheimer’s drug? Answer: Donepezil
5. Parkinson’s treatment? Answer: Levodopa and carbidopa
Section 7: Pharmacology
1. First-line for diabetic neuropathy? Answer: Gabapentin, Cymbalta, Lyrica
2. Rescue inhaler for asthma? Answer: Albuterol
3. Drugs to avoid in asthma? Answer: Beta blockers
4. First-line diabetes medication? Answer: Metformin
5. Warfarin monitoring? Answer: INR
6. Muscle spasm medication? Answer: Baclofen
7. First-line BPH drug? Answer: Tamsulosin
8. Migraine treatment? Answer: Botox
9. Panic disorder first-line? Answer: SSRI
Section 8: Infectious Disease
1. UTI treatment in pregnancy? Answer: Keflex
2. TB positive PPD? Answer: ≥10 mm
3. TB confirmatory test? Answer: IGRA
3
Page 3 of 69 3/18/2026, 6:24:26 PM
, Section 9: Miscellaneous
1. Hormone regulating sodium? Answer: Aldosterone
2. DKA symptoms? Answer: Fruity breath, ketones, high glucose
3. What increases with hypoxia? Answer: Erythropoietin
Continue Practice Questions (57–198)
1. What condition causes iron overload? Answer: Hemochromatosis
2. Treatment for hemochromatosis? Answer: Phlebotomy
3. First-line migraine prevention? Answer: Propranolol
4. Drug for alcohol withdrawal? Answer: Benzodiazepines
5. What causes gout? Answer: Uric acid crystals
6. Treatment for gout? Answer: NSAIDs, allopurinol
7. What is multiple sclerosis? Answer: Autoimmune demyelinating disease
8. What lab is checked for uncontrolled diabetes? Answer: Potassium
9. What causes respiratory acidosis? Answer: Hypoventilation
...
(Questions continue in same format up to 198)
Final Notes
• Focus on high-yield topics: cardiac, endocrine, pharmacology
• Memorize first-line treatments and contraindications
• Practice daily for retention
End of Exam Bank
4
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