, 1
Chapter 01: Introduction to Pathophysiology
55 55 55 55
VanMeterand Hubert: Gould’s Pathophysiology for the Health Professions, 7th Edition
55 55 55 55 55 55 55 55 55 55
MULTIPLE CHOICE 55
1. Which of the following would be the most likely cause of an
55 55 55 55 55 55 55 55 55 55 55
iatrogenic disease?
55 55
a. An inherited disorder 55 55
b. A combination of specific etiological factors
55 55 55 55 55
c. An unwanted effect of a prescribed drug
55 55 55 55 55 55
d. Prolonged exposure to toxic chemicals in the environment 55 55 55 55 55 55 55
ANS: C 55
2. The manifestations of a disease are best defined as the
55 55 55 55 55 55 55 55 55
a. subjective feelings of discomfort during a chronic illness. 55 55 55 55 55 55 55
b. signs and symptoms of a disease. 55 55 55 55 55
c. factors that precipitate an acute episode of a chronic illness.
55 55 55 55 55 55 55 55 55
d. early indicators of the prodromal stage of infection.
55 55 55 55 55 55 55
ANS: B 55
3. The best definition of the term prognosis is the
55 55 55 55 55 55 55 55
a. precipitating factors causing an acute episode. 55 55 55 55 55
b. number of remissions to be expected during the course of a chronic illness.
55 55 55 55 55 55 55 55 55 55 55 55
c. predicted outcome or likelihood of recovery from a specific disease. 55 55 55 55 55 55 55 55 55
d. exacerbations occurring during chronic illness. 5 55 55 55
ANS: C 55
4. Which of the following is considered a systemic sign of disease?
55 55 55 55 55 55 55 55 55 55
a. Swelling of the knee 55 55 55
b. Fever
c. Pain in the neck 55 55 55
d. Red rash on the face 55 55 55 55
ANS: B 55
5. Etiology is defined as the study of the 55 55 55 55 55 55 55
a. causes of a disease. 55 55 55
b. course of a disease. 55 55 55
c. expected complications of a disease. 55 55 55 55
d. manifestations of a disease. 55 55 55
ANS: A 55
6. A type of cellular adaptation in which there is a decrease in cell size is referred to as
55 55 55 55 55 55 55 55 55 55 55 55 55 55 55 55 55
a. hypertrophy.
b. metaplasia.
c. anaplasia.
d. atrophy.
ANS: D 55
7. A change in a tissue marked by cells that vary in size and shape and show increased
55 55 55 55 55 55 55 55 55 55 55 55 55 55 55 55
55mitotic figures would be called
55 55 55 55
,Test Bank For Gould's Pathophysiology for the Health Professions 7th Edition VanMeter
55 55 55 55 55 55 55 55 55 55 55 2
a. metaplasia.
b. atrophy.
c. dysplasia.
d. hypertrophy.
ANS: C 55
8. A deficit of oxygen in the cells usually due to respiratory or circulatory problems is called
55 55 55 55 55 55 55 55 55 55 55 55 55 55 55
a. apoptosis.
b. ischemia.
c. hypertrophy.
d. necrosis.
ANS: B 55
9. When a group of cells in the body dies, the change is called
55 55 55 55 55 55 55 55 55 55 55 55
a. ischemia.
b. gangrene.
c. hypoxia.
d. necrosis.
ANS: D 55
10. Rigorous weightlifting/body building regimens may result in the skeletal muscle
55 55 55 55 55 55 55 55 55
55cells undergoing 55
a. hypertrophy.
b. dysplasia.
c. atrophy.
d. regeneration.
ANS: A 55
11. The term cancer refers to
55 55 55 55
a. dysplasia.
b. hyperplasia.
c. metaplasia.
d. malignant neoplasm. 55
ANS: D 55
12. To which of the following does the term apoptosis refer?
55 55 55 55 55 55 55 55 55
a. Increased rate of mitosis by certain cells 55 55 55 55 55 55
b. Ischemic damage to cells 55 55 55
c. Liquefaction of necrotic tissue 55 55 55
d. Preprogrammed cell self-destruction 55 55
ANS: D 55
13. Which of the following statements is TRUE?
55 55 55 55 55 55
a. Alteration of DNA does not change cell function. 55 55 55 55 55 55 55
b. Damaged cells may be able to repair themselves. 55 55 55 55 55 55 55
c. All types of cells die at the same rate.
55 55 55 55 55 55 55 55
d. Mild ischemia causes immediate cell death. 55 55 55 55 55
ANS: B 55
14. Caseation necrosis refers to an area where 55 55 55 55 55 55
a. cell proteins have been denatured. 55 55 55 55
, Test Bank For Gould's Pathophysiology for the Health Professions 7th Edition VanMeter
55 55 55 55 55 55 55 55 55 55 55 3
b. cells are liquefied by enzymes. 55 55 55 55
c. dead cells form a thick cheesy substance. 55 55 55 55 55 55
d. bacterial invasion has occurred. 55 55 55
ANS: C 55
15. Routine application of sun block to skin would be an example of
55 55 55 55 55 55 55 55 55 55 55
a. an iatrogenic cause of cancer.
55 55 55 55
b. a preventive measure.
55 55
c. a precipitating factor.
55 55
d. a predisposing condition.
55 55
ANS: B 55
16. A circumstance that causes a sudden acute episode of a chronic disease to occur is termed
55 55 55 55 55 55 55 55 55 55 55 55 55 55 55
a. latent stage. 55
b. predisposing factor. 55
c. incidence.
d. precipitating factor. 55
ANS: D 55
17. The term homeostasis refers to
55 55 55 55
a. the causative factors in a particular disease.
55 55 55 55 55 55
b. maintenance of a stable internal environment. 55 55 55 55 55
c. a condition that triggers an acute episode.
55 55 55 55 55 55
d. a collection of signs and symptoms.
55 55 55 55 55
ANS: B 55
18. Which term is used to describe a new and secondary or additional problem that arises after
55 55 55 55 55 55 55 55 55 55 55 55 55 55 55
55the original disease has been established?
55 55 55 55 55
a. Symptoms
b. Occurrence
c. Manifestations
d. Complication
ANS: D 55
19. Pathophysiology involves the study of 55 55 55 55
a. the structure of the human body. 55 55 55 55 55
b. the functions of various organs in the body.
55 55 55 55 55 55 55
c. functional or structural changes resulting from disease processes. 55 55 55 55 55 55 55
d. various cell structures and related functions. 55 55 55 55 55
ANS: C 55
20. Which of the following is the best definition of epidemiology?
55 55 55 55 55 55 55 55 55
a. The science of tracking the occurrence and distribution of diseases
55 55 55 55 55 55 55 55 55
b. The relative number of deaths resulting from a particular disease
55 55 55 55 55 55 55 55 55
c. Identification of a specific disease through evaluation of signs and symptoms 55 55 55 55 55 55 55 55 55 55
d. The global search for emerging diseases55 55 55 55 55
ANS: A 55
Chapter 01: Introduction to Pathophysiology
55 55 55 55
VanMeterand Hubert: Gould’s Pathophysiology for the Health Professions, 7th Edition
55 55 55 55 55 55 55 55 55 55
MULTIPLE CHOICE 55
1. Which of the following would be the most likely cause of an
55 55 55 55 55 55 55 55 55 55 55
iatrogenic disease?
55 55
a. An inherited disorder 55 55
b. A combination of specific etiological factors
55 55 55 55 55
c. An unwanted effect of a prescribed drug
55 55 55 55 55 55
d. Prolonged exposure to toxic chemicals in the environment 55 55 55 55 55 55 55
ANS: C 55
2. The manifestations of a disease are best defined as the
55 55 55 55 55 55 55 55 55
a. subjective feelings of discomfort during a chronic illness. 55 55 55 55 55 55 55
b. signs and symptoms of a disease. 55 55 55 55 55
c. factors that precipitate an acute episode of a chronic illness.
55 55 55 55 55 55 55 55 55
d. early indicators of the prodromal stage of infection.
55 55 55 55 55 55 55
ANS: B 55
3. The best definition of the term prognosis is the
55 55 55 55 55 55 55 55
a. precipitating factors causing an acute episode. 55 55 55 55 55
b. number of remissions to be expected during the course of a chronic illness.
55 55 55 55 55 55 55 55 55 55 55 55
c. predicted outcome or likelihood of recovery from a specific disease. 55 55 55 55 55 55 55 55 55
d. exacerbations occurring during chronic illness. 5 55 55 55
ANS: C 55
4. Which of the following is considered a systemic sign of disease?
55 55 55 55 55 55 55 55 55 55
a. Swelling of the knee 55 55 55
b. Fever
c. Pain in the neck 55 55 55
d. Red rash on the face 55 55 55 55
ANS: B 55
5. Etiology is defined as the study of the 55 55 55 55 55 55 55
a. causes of a disease. 55 55 55
b. course of a disease. 55 55 55
c. expected complications of a disease. 55 55 55 55
d. manifestations of a disease. 55 55 55
ANS: A 55
6. A type of cellular adaptation in which there is a decrease in cell size is referred to as
55 55 55 55 55 55 55 55 55 55 55 55 55 55 55 55 55
a. hypertrophy.
b. metaplasia.
c. anaplasia.
d. atrophy.
ANS: D 55
7. A change in a tissue marked by cells that vary in size and shape and show increased
55 55 55 55 55 55 55 55 55 55 55 55 55 55 55 55
55mitotic figures would be called
55 55 55 55
,Test Bank For Gould's Pathophysiology for the Health Professions 7th Edition VanMeter
55 55 55 55 55 55 55 55 55 55 55 2
a. metaplasia.
b. atrophy.
c. dysplasia.
d. hypertrophy.
ANS: C 55
8. A deficit of oxygen in the cells usually due to respiratory or circulatory problems is called
55 55 55 55 55 55 55 55 55 55 55 55 55 55 55
a. apoptosis.
b. ischemia.
c. hypertrophy.
d. necrosis.
ANS: B 55
9. When a group of cells in the body dies, the change is called
55 55 55 55 55 55 55 55 55 55 55 55
a. ischemia.
b. gangrene.
c. hypoxia.
d. necrosis.
ANS: D 55
10. Rigorous weightlifting/body building regimens may result in the skeletal muscle
55 55 55 55 55 55 55 55 55
55cells undergoing 55
a. hypertrophy.
b. dysplasia.
c. atrophy.
d. regeneration.
ANS: A 55
11. The term cancer refers to
55 55 55 55
a. dysplasia.
b. hyperplasia.
c. metaplasia.
d. malignant neoplasm. 55
ANS: D 55
12. To which of the following does the term apoptosis refer?
55 55 55 55 55 55 55 55 55
a. Increased rate of mitosis by certain cells 55 55 55 55 55 55
b. Ischemic damage to cells 55 55 55
c. Liquefaction of necrotic tissue 55 55 55
d. Preprogrammed cell self-destruction 55 55
ANS: D 55
13. Which of the following statements is TRUE?
55 55 55 55 55 55
a. Alteration of DNA does not change cell function. 55 55 55 55 55 55 55
b. Damaged cells may be able to repair themselves. 55 55 55 55 55 55 55
c. All types of cells die at the same rate.
55 55 55 55 55 55 55 55
d. Mild ischemia causes immediate cell death. 55 55 55 55 55
ANS: B 55
14. Caseation necrosis refers to an area where 55 55 55 55 55 55
a. cell proteins have been denatured. 55 55 55 55
, Test Bank For Gould's Pathophysiology for the Health Professions 7th Edition VanMeter
55 55 55 55 55 55 55 55 55 55 55 3
b. cells are liquefied by enzymes. 55 55 55 55
c. dead cells form a thick cheesy substance. 55 55 55 55 55 55
d. bacterial invasion has occurred. 55 55 55
ANS: C 55
15. Routine application of sun block to skin would be an example of
55 55 55 55 55 55 55 55 55 55 55
a. an iatrogenic cause of cancer.
55 55 55 55
b. a preventive measure.
55 55
c. a precipitating factor.
55 55
d. a predisposing condition.
55 55
ANS: B 55
16. A circumstance that causes a sudden acute episode of a chronic disease to occur is termed
55 55 55 55 55 55 55 55 55 55 55 55 55 55 55
a. latent stage. 55
b. predisposing factor. 55
c. incidence.
d. precipitating factor. 55
ANS: D 55
17. The term homeostasis refers to
55 55 55 55
a. the causative factors in a particular disease.
55 55 55 55 55 55
b. maintenance of a stable internal environment. 55 55 55 55 55
c. a condition that triggers an acute episode.
55 55 55 55 55 55
d. a collection of signs and symptoms.
55 55 55 55 55
ANS: B 55
18. Which term is used to describe a new and secondary or additional problem that arises after
55 55 55 55 55 55 55 55 55 55 55 55 55 55 55
55the original disease has been established?
55 55 55 55 55
a. Symptoms
b. Occurrence
c. Manifestations
d. Complication
ANS: D 55
19. Pathophysiology involves the study of 55 55 55 55
a. the structure of the human body. 55 55 55 55 55
b. the functions of various organs in the body.
55 55 55 55 55 55 55
c. functional or structural changes resulting from disease processes. 55 55 55 55 55 55 55
d. various cell structures and related functions. 55 55 55 55 55
ANS: C 55
20. Which of the following is the best definition of epidemiology?
55 55 55 55 55 55 55 55 55
a. The science of tracking the occurrence and distribution of diseases
55 55 55 55 55 55 55 55 55
b. The relative number of deaths resulting from a particular disease
55 55 55 55 55 55 55 55 55
c. Identification of a specific disease through evaluation of signs and symptoms 55 55 55 55 55 55 55 55 55 55
d. The global search for emerging diseases55 55 55 55 55
ANS: A 55
