NCLEX-RN CASE STUDY: DIABETES INSIPIDUS
(DI)
Client Scenario
0900 Nurses' Notes:
A 34-year-old male is admitted to the neurological step-down unit following a traumatic
brain injury (TBI) from a motorcycle accident. The night shift nurse reports that the client’s
urine output has increased dramatically over the last 4 hours. The client is awake and
complaining of "unquenchable thirst."
Physical Assessment:
General: Alert and oriented x3; appearing restless.
Integumentary: Mucous membranes are dry; skin turgor is poor (tenting noted).
Urinary: Large amounts of very pale, straw-colored urine in the collection bag.
Output was 600 mL in the last hour.
Vital Signs: BP 94/60, HR 118, RR 20, Temp 99.0°F.
Item 1: Recognizing Cues (Visual/Diagram)
Question: The nurse reviews the relationship between the hypothalamus, pituitary gland,
and the kidneys. Which diagram correctly illustrates the pathophysiology of Neurogenic
Diabetes Insipidus?
Correct Findings to Identify:
✅Decreased Antidiuretic Hormone (ADH) production/release.
✅Inability of the distal tubules to reabsorb water.
✅Massive diuresis (polyuria).
✅Increased serum osmolality (dehydration).
Rationale: In neurogenic DI (often caused by head trauma), the posterior pituitary fails to
secrete ADH. Without ADH, the kidneys cannot "hold onto" water, leading to massive dilute
urine output and systemic dehydration.