Medication Safety 3rd Edition Test Bank |
Verified Questions & Answers | 2025 –
2026 All Revised Exams Attached By Past
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Which is a common side effect of thyroid hormone agonists when taken in overdose?
A. Weight gain
B. Bradycardia
C. Symptoms of hyperthyroidism
D. Edema
Answer: C. Symptoms of hyperthyroidism
Rationale: Excess thyroid hormone overstimulates metabolism, causing tachycardia,
insomnia, and diarrhea.
Thyroid hormone agonists mimic which hormones?
A. TSH and TRH
B. T3 and T4
C. Calcitonin and PTH
D. Cortisol and Aldosterone
Answer: B. T3 and T4
Rationale: These hormones regulate metabolism and growth.
Which of the following is a sign of hypothyroidism in adults?
A. Tachycardia and weight loss
B. Thick, waxy skin and lethargy
C. Diarrhea and insomnia
D. Goiter with rapid metabolism
Answer: B. Thick, waxy skin and lethargy
Rationale: Hypothyroidism slows metabolism, causing weight gain, edema, and lethargy.
,Which symptom is most common in hypothyroid children?
A. Weight loss and tachycardia
B. Protruding tongue and short stature
C. Diarrhea and insomnia
D. Rapid heart rate and sweating
Answer: B. Protruding tongue and short stature
Rationale: Hypothyroidism in children can lead to growth retardation and developmental
delays.
What is a goiter?
A. Excess cortisol production
B. Swelling in the neck due to thyroid abnormality
C. Low aldosterone levels
D. Overactive adrenal medulla
Answer: B. Swelling in the neck due to thyroid abnormality
Rationale: Enlarged thyroid can occur in both hypo- and hyperthyroidism.
Which is a severe, life-threatening form of hypothyroidism?
A. Thyroid storm
B. Myxedema
C. Hyperaldosteronism
D. Cushing’s disease
Answer: B. Myxedema
Rationale: Requires immediate medical attention due to profound metabolic slowing.
Which corticosteroid regulates sodium and water balance?
A. Cortisol
B. Aldosterone
C. T3
D. T4
Answer: B. Aldosterone
Rationale: Aldosterone is a mineralocorticoid secreted by the adrenal cortex to maintain
fluid and electrolyte balance.
,Prednisone is primarily used to:
A. Replace aldosterone
B. Replace cortisol
C. Suppress thyroid function
D. Treat hyperkalemia
Answer: B. Replace cortisol
Rationale: Corrects glucocorticoid deficiency in adrenal insufficiency.
Fludrocortisone (Florinef) acts like:
A. Cortisol
B. Aldosterone
C. T3
D. Insulin
Answer: B. Aldosterone
Rationale: Increases sodium reabsorption and potassium excretion to maintain electrolyte
balance.
Which is a serious adverse effect of fludrocortisone?
A. Hypotension
B. Congestive heart failure
C. Hypokalemia only
D. Hyperglycemia
Answer: B. Congestive heart failure
Rationale: Sodium retention can exacerbate heart failure.
Common signs of hyperthyroidism include:
A. Bradycardia and lethargy
B. Diarrhea, tachycardia, and weight loss
C. Thick skin and edema
D. Short stature and protruding tongue
Answer: B. Diarrhea, tachycardia, and weight loss
Rationale: Overactive thyroid increases metabolic rate and cardiac activity.
Which drug is stronger for thyroid suppression?
A. Propylthiouracil
, B. Methimazole
C. Fludrocortisone
D. Prednisone
Answer: B. Methimazole
Rationale: Methimazole is approximately 10 times more potent than propylthiouracil.
Thyroid-suppressing drugs are contraindicated in:
A. Elderly patients
B. Pregnant or breastfeeding women
C. Male adults
D. Patients with diabetes
Answer: B. Pregnant or breastfeeding women
Rationale: High risk of birth defects and fetal damage.
Which is a key sign of adrenal hypofunction?
A. Hyperglycemia
B. Hypertension
C. Hypotension and salt craving
D. Weight gain
Answer: C. Hypotension and salt craving
Rationale: Low cortisol and aldosterone reduce sodium retention and blood pressure.
Cushing’s disease results from:
A. Cortisol deficiency
B. Cortisol excess
C. Aldosterone deficiency
D. Thyroid hormone deficiency
Answer: B. Cortisol excess
Rationale: Hypercortisolism leads to obesity, hypertension, and metabolic changes.
Which drug blocks cortisol receptors in hypercortisolism?
A. Mitotane
B. Mifepristone
C. Fludrocortisone
D. Prednisone
Verified Questions & Answers | 2025 –
2026 All Revised Exams Attached By Past
Papers | Graded A + | 100 % Guaranteed
Pass
Which is a common side effect of thyroid hormone agonists when taken in overdose?
A. Weight gain
B. Bradycardia
C. Symptoms of hyperthyroidism
D. Edema
Answer: C. Symptoms of hyperthyroidism
Rationale: Excess thyroid hormone overstimulates metabolism, causing tachycardia,
insomnia, and diarrhea.
Thyroid hormone agonists mimic which hormones?
A. TSH and TRH
B. T3 and T4
C. Calcitonin and PTH
D. Cortisol and Aldosterone
Answer: B. T3 and T4
Rationale: These hormones regulate metabolism and growth.
Which of the following is a sign of hypothyroidism in adults?
A. Tachycardia and weight loss
B. Thick, waxy skin and lethargy
C. Diarrhea and insomnia
D. Goiter with rapid metabolism
Answer: B. Thick, waxy skin and lethargy
Rationale: Hypothyroidism slows metabolism, causing weight gain, edema, and lethargy.
,Which symptom is most common in hypothyroid children?
A. Weight loss and tachycardia
B. Protruding tongue and short stature
C. Diarrhea and insomnia
D. Rapid heart rate and sweating
Answer: B. Protruding tongue and short stature
Rationale: Hypothyroidism in children can lead to growth retardation and developmental
delays.
What is a goiter?
A. Excess cortisol production
B. Swelling in the neck due to thyroid abnormality
C. Low aldosterone levels
D. Overactive adrenal medulla
Answer: B. Swelling in the neck due to thyroid abnormality
Rationale: Enlarged thyroid can occur in both hypo- and hyperthyroidism.
Which is a severe, life-threatening form of hypothyroidism?
A. Thyroid storm
B. Myxedema
C. Hyperaldosteronism
D. Cushing’s disease
Answer: B. Myxedema
Rationale: Requires immediate medical attention due to profound metabolic slowing.
Which corticosteroid regulates sodium and water balance?
A. Cortisol
B. Aldosterone
C. T3
D. T4
Answer: B. Aldosterone
Rationale: Aldosterone is a mineralocorticoid secreted by the adrenal cortex to maintain
fluid and electrolyte balance.
,Prednisone is primarily used to:
A. Replace aldosterone
B. Replace cortisol
C. Suppress thyroid function
D. Treat hyperkalemia
Answer: B. Replace cortisol
Rationale: Corrects glucocorticoid deficiency in adrenal insufficiency.
Fludrocortisone (Florinef) acts like:
A. Cortisol
B. Aldosterone
C. T3
D. Insulin
Answer: B. Aldosterone
Rationale: Increases sodium reabsorption and potassium excretion to maintain electrolyte
balance.
Which is a serious adverse effect of fludrocortisone?
A. Hypotension
B. Congestive heart failure
C. Hypokalemia only
D. Hyperglycemia
Answer: B. Congestive heart failure
Rationale: Sodium retention can exacerbate heart failure.
Common signs of hyperthyroidism include:
A. Bradycardia and lethargy
B. Diarrhea, tachycardia, and weight loss
C. Thick skin and edema
D. Short stature and protruding tongue
Answer: B. Diarrhea, tachycardia, and weight loss
Rationale: Overactive thyroid increases metabolic rate and cardiac activity.
Which drug is stronger for thyroid suppression?
A. Propylthiouracil
, B. Methimazole
C. Fludrocortisone
D. Prednisone
Answer: B. Methimazole
Rationale: Methimazole is approximately 10 times more potent than propylthiouracil.
Thyroid-suppressing drugs are contraindicated in:
A. Elderly patients
B. Pregnant or breastfeeding women
C. Male adults
D. Patients with diabetes
Answer: B. Pregnant or breastfeeding women
Rationale: High risk of birth defects and fetal damage.
Which is a key sign of adrenal hypofunction?
A. Hyperglycemia
B. Hypertension
C. Hypotension and salt craving
D. Weight gain
Answer: C. Hypotension and salt craving
Rationale: Low cortisol and aldosterone reduce sodium retention and blood pressure.
Cushing’s disease results from:
A. Cortisol deficiency
B. Cortisol excess
C. Aldosterone deficiency
D. Thyroid hormone deficiency
Answer: B. Cortisol excess
Rationale: Hypercortisolism leads to obesity, hypertension, and metabolic changes.
Which drug blocks cortisol receptors in hypercortisolism?
A. Mitotane
B. Mifepristone
C. Fludrocortisone
D. Prednisone
