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A 44 year-old female presents for follow-up results of her lipid profile. She is
asymptomatic and has a past medical
history of hypothyroidism treated with levothyroxine and hypertension controlled with
atenolol (Tenormin). She drinks an average of 6 alcoholic beverages a day and smokes 1
pack per day for the last 32 years. Her family history is unremarkable for premature
coronary artery disease. Her fasting blood glucose is 98 mg/dL, total cholesterol is 198
mg/dL, LDL cholesterol is 132 mg/dL, HDL cholesterol is 56 mg/dL and triglycerides of
90 mg/dL. Excluding LDL cholesterol levels, how many major risk factors for coronary
artery disease does this female possess?
A. 2
B. 3
C. 4
D. 5
(c) A. This patient's major cardiac risk factors are smoking and hypertension in addition to
the elevated LDL
cholesterol.
(u) B. See A for explanation.
(u) C. See A for explanation.
(u) D. See A for explanation.
,A 65 year-old patient with steroid-dependent chronic obstructive lung disease presents
with a headache that has been increasing in severity over the past week, accompanied
by nausea and vomiting. He denies fever, but has had photophobia and a stiff neck.
Which of the following is the most likely diagnosis?
A. Transient ischemic attack
B. Bacterial meningitis
C. Migraine headache
D. Cryptococcosis
(u) A. Transient ischemic attacks present with focal neurological findings rather than
headaches.
(a) B. Bacterial meningitis is typically acute in onset and causes fever, but
immunocompromised patients may have a slower onset and no fever.
(u) C. Migraines generally do not begin in this age group, and are not accompanied by
nuchal rigidity.
(c) D.Cryptococcus is an opportunistic fungal infection that affects immunocompromised
patients, including those with HIV, chronic steroid use, organ transplants, diabetes
mellitus, and chronic renal or liver disease. The most common clinical presentation is that
of meningitis; fever is present in only about half of patients.
,A 40 year-old female presents with a 1.5 cm well-circumscribed mass noted on
mammography in the right upper, outer quadrant. Which of the following procedures is
most appropriate and should be done next?
A. Fine needle aspiration
B. BRCA 1 and BRCA 2 genetic testing
C. Serum CA-125
D. Radiation therapy
(c) A. Fine needle aspiration is fairly accurate, easily performed, and has minimal
morbidity.
(u) B. Although BRCA 1 and BRCA 2 genetic tests are used in the risk assessment for
possible breast and ovarian cancer, it would not replace the need to perform a more
definitive evaluation of an identified breast mass.
(u) C. Serum CA-125 is a tumor marker for ovarian, not breast, cancer.
(u) D. Radiation therapy is only indicated after a diagnosis of breast cancer is proven and
may be used as adjunctive therapy.
On examination of a pregnant patient the physician assistant notes the fundal height is at
the level of the umbilicus. This corresponds to what gestational age?
A. 16 weeks
B. 20 weeks
C. 24 weeks
D. 28 weeks
(u) A. See B for explanation.
(c) B. At 20-22 weeks, the fundal height is typically at the level of the umbilicus.
(u) C. See B for explanation.
(u) D. See B for explanation.
, Which of the following is a common symptom associated with laryngotracheobronchitis
(viral croup)?
A. Drooling
B. High fever
C. "Hot potato" voice
D. Barking cough
(u) A. Drooling and a "hot potato" voice are seen with epiglottitis, not viral croup.
(u) B. Fever is usually absent or low-grade in patients with viral croup.
(u) C. See A for explanation.
(c) D. Viral croup is characterized by a history of upper respiratory tract symptoms
followed by onset of a barking cough and stridor.