Pharm Exam 1 Key Concepts – Questions &
Answers | Accurate Solutions
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Practice questions for this set
Learn 1 /7 Study using Learn
One drug reduces or blocks the effect of another drug
Choose an answer
Pharmacodynamic interactions:
1 2 Pharmacology
Antagonistic
3 MOA: Replacement 4 Antagonist
Don't know?
Terms in this set (130)
Pharmacology -Study of drugs and their interactions with living
systems
-Maximum benefit, minimum side effects
,Drug receptor -Target for a drug
-Any functional macromolecule in a cell to which a
drug binds to produce its effect
-Think lock and key
-Some receptors are on cell surface, and some are in
the cell
-Most receptors are proteins, better the drug fits the
receptor, the more active the drug
Receptor theory The proteins tell the cells to activate or inactivate or
to produce or block a response
Agonist -Activates receptors
-Turns ON a cell response
-Both affinity & high intrinsic activity
Antagonist -Block receptors in the body
-Prevents activation of the receptor
-Has affinity but no intrinsic activation
Partial agonist -Lower effect than the full agonist
-May be an agonist at some receptor sites or an
antagonist at others
Non-receptor responses -Does NOT need a receptor for desired action
-May kill bacteria, antacids, immunotherapies
Non-specific effects Drug effects one receptor, but at multiple sites in the
body
Non-selective effects -One drug affects multiple types of receptors
-Different receptors
-Ex: Alpha1, beta1, beta2
, MOA: Stimulation Drug that stimulates enhances intrinsic activity
(increase HR, RR, sweating)
MOA: Depression Decrease neural activity & bodily functions (opiates)
MOA: Irritation -Drugs that irritate produce a noxious effect (harmful
or injurious influence on mind or body)
-Astringents
MOA: Replacement -Replace essential body compounds
-Insulin, hormones, thyroid drugs
MOA: Cytotoxic action -Selectively kill invading parasites or cancers
MOA: Antimicrobial action -Prevent, inhibit, or kill infectious organisms
MOA: Modification of immune status -Modify, enhance, or depress the immune system
Pharmacodynamic interactions: -Combined effect of 2 of more drugs is equal to the
Additive sum of their individual effects
-Drugs work through the same or similar mechanisms
of action & do not interfere with each others actions
Pharmacodynamic interactions: -Effect is much greater together than effects of either
Synergistic drug alone
-Think of Carbadopa/levodopa
Pharmacodynamic interactions: One drug reduces or blocks the effect of another
Antagonistic drug
Drug-nutrient interactions -Foods may increase, decrease, or delay drug
response
-Grapefruit juice interferes with a lot of drugs
Drug-lab interactions -Drug may cause a misinterpretation of lab results
-Like a blood test
Answers | Accurate Solutions
Save
Practice questions for this set
Learn 1 /7 Study using Learn
One drug reduces or blocks the effect of another drug
Choose an answer
Pharmacodynamic interactions:
1 2 Pharmacology
Antagonistic
3 MOA: Replacement 4 Antagonist
Don't know?
Terms in this set (130)
Pharmacology -Study of drugs and their interactions with living
systems
-Maximum benefit, minimum side effects
,Drug receptor -Target for a drug
-Any functional macromolecule in a cell to which a
drug binds to produce its effect
-Think lock and key
-Some receptors are on cell surface, and some are in
the cell
-Most receptors are proteins, better the drug fits the
receptor, the more active the drug
Receptor theory The proteins tell the cells to activate or inactivate or
to produce or block a response
Agonist -Activates receptors
-Turns ON a cell response
-Both affinity & high intrinsic activity
Antagonist -Block receptors in the body
-Prevents activation of the receptor
-Has affinity but no intrinsic activation
Partial agonist -Lower effect than the full agonist
-May be an agonist at some receptor sites or an
antagonist at others
Non-receptor responses -Does NOT need a receptor for desired action
-May kill bacteria, antacids, immunotherapies
Non-specific effects Drug effects one receptor, but at multiple sites in the
body
Non-selective effects -One drug affects multiple types of receptors
-Different receptors
-Ex: Alpha1, beta1, beta2
, MOA: Stimulation Drug that stimulates enhances intrinsic activity
(increase HR, RR, sweating)
MOA: Depression Decrease neural activity & bodily functions (opiates)
MOA: Irritation -Drugs that irritate produce a noxious effect (harmful
or injurious influence on mind or body)
-Astringents
MOA: Replacement -Replace essential body compounds
-Insulin, hormones, thyroid drugs
MOA: Cytotoxic action -Selectively kill invading parasites or cancers
MOA: Antimicrobial action -Prevent, inhibit, or kill infectious organisms
MOA: Modification of immune status -Modify, enhance, or depress the immune system
Pharmacodynamic interactions: -Combined effect of 2 of more drugs is equal to the
Additive sum of their individual effects
-Drugs work through the same or similar mechanisms
of action & do not interfere with each others actions
Pharmacodynamic interactions: -Effect is much greater together than effects of either
Synergistic drug alone
-Think of Carbadopa/levodopa
Pharmacodynamic interactions: One drug reduces or blocks the effect of another
Antagonistic drug
Drug-nutrient interactions -Foods may increase, decrease, or delay drug
response
-Grapefruit juice interferes with a lot of drugs
Drug-lab interactions -Drug may cause a misinterpretation of lab results
-Like a blood test
