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Terms in this set (637)
*The FDA's 2022 #256 GFI did what? Restricted access to previous OTC antimicrobial
drugs
Restricted/allowed compounding with certain bulk
drug substances
***What 3 things are necessary for 1. Understand drug's pharmacokinetics
therapeutic drug monitoring (TDM)? 2. Understand drug's pharmacodynamics
3. Drug has low therapeutic index
What is an empiric antibiotic? Making an "educated guess" on what antibiotic
should be used know the species, infection location,
and bacteria shape/gram type
A dog weighs 13.2 lbs (6 kgs) 6 * 4 = 24mg SID
Carprofen should be given at 4mg/kg So 1 tablet once daily
PO per day and you have 25mg
tablets.
How should this animal be dosed?
A dog weighs 13.2 lbs (6 kgs) 6 * 15 = 90mg q 8-12 hrs
Amoxicillin should be given at 90/50 = 1.8mls q 12 hours
15mg/kg PO q8-12hrs and you have a
50mg/ml suspension
Should you talk to the owner about YES
side effect risks? Warn them what to look out for so you can intervene
What is a drug? A substance used in the treatment, diagnosis,
prevention, or mitigation of a disease
,A _____________ is a substance used in the drug
treatment, diagnosis, prevention, or
mitigation of a disease
What are the 4 types of drugs? Endogenous
Natural
Semisynthetic
Synthetic
_____________ are a branch of medical Therapeutics
science dealing with the application
of remedies to diseases
____________ is the scientific study of the Pharmacology
effects of drugs and chemicals on a
living organism; concerned with the
uses, effects, and modes of actions of
drugs
_____________ is the branch of Clinical pharmacology
pharmacology that deals directly with
the effectiveness and safety of drugs
in a clinical setting
___________ is a separate and Pharmacy
complementary health-care
profession concerned with the
collection, preparation,
standardization, and dispensing of
drugs; the practice of preparing,
preserving, compounding, and
dispensing drugs
What does ADME stand for? (describes the disposition of a drug)
Absorption
Distribution
Metabolism
Excretion
,***____________ is the branch of Pharmacokinetics
pharmacology concerned with the
movement of drugs within the body
***_____________ is the branch of Pharmicodynamics
pharmacology concerned with the
effects of drugs and the mechanism of
their action
What is an active ingredient? The actual drug
What is the excipient of a drug? A substance other than the active ingredient that is
evaluated and intentionally included
Often used to bulk up solid formulations in
compounding, like lactose
The ___________ of a drug is the actual active ingredient
drug
The ____________ of a drug is a substance vehicle
used in the process of drug delivery
The _______________ of a drug is a excipient
substance other than the active
ingredient that is evaluated and
intentionally included. Often used to
bulk up solid formulations in
compounding, like lactose
The ___________ of a drug binds binder
ingredients together, like gelatin
Give examples (3) of common liquid Solution
drug formulations Suspension
Emulsion
, A _____________ is a homogenous mixture solution
formed by mixing a solid, liquid, or
gaseous substance with a liquid
What is a solution? A homogenous mixture of a solid/liquid/gas with a
liquid
A ___________ are drugs with insoluble suspension
solid particles can be dispersed in a
liquid medium; must be shaken well
before giving to patient
What is a suspension? Insoluble solid particles in a liquid; must be shaken
well before giving to patient
A ___________ is a mixture of 2+ liquids that emulsion
are normally immiscible/unmixable
owing to liquid-liquid phase
separation
What is an emulsion? 2+ liquids mixed that are normally unmixable