3610 PATH 2025 Final Exam Review | Verified Questions and
Answers
Death of cells in a living organism is termed:
1) Gangrene
2) Necrosis
3) Ischemia - CORRECT ANSWER>>>>Necrosis
Apoptosis refers to:
1) The internalization of material by a cell
2) Disintegration of tissues which occurs after death
3) Programmed cell death - CORRECT ANSWER>>>>Programmed cell death
A myocardial infarct is seen as a dry, well demarcated area of pale tissue. This would
be described as:
1) Coagulation necrosis
2) Caseation necrosis
3) An abscess - CORRECT ANSWER>>>>Coagulation necrosis
Free radicals can impair cell membrane function by causing:
1) Lesions in DNA
2) Lipid peroxidation
3) Protein cross-linking - CORRECT ANSWER>>>>Lipid peroxidation
Starvation can lead to the development of fatty liver.
True or false? - CORRECT ANSWER>>>>True
Regional tissue necrosis due to ischemia, followed by secondary bacterial infection defines:
1) Autolysis
2) Putrefaction
3) Gangrene - CORRECT ANSWER>>>>Gangrene
Hypoxia, leading to impaired energy production by the cell, may be caused by:
1) Anemia
1
,2) Low blood glucose levels
3) Inhibition of respiratory enzymes - CORRECT ANSWER>>>>Anemia
The primary change in hemolytic jaundice is:
1) Inadequate bilirubin excretion
2) Increased production of bilirubin
3) Serum accumulation of conjugated bilirubin - CORRECT
ANSWER>>>>Increased production of bilirubin
Bilirubin is:
1) Lipid soluble when conjugated
2) Water soluble when conjugated
3) Conjugated in the kidney for excretion in the urine - CORRECT
ANSWER>>>>Water soluble when conjugated
Cellular injury can result when bilirubin accumulates in:
1) Parenchymal cells (such as the liver or brain)
2) Connective tissue
3) Skin - CORRECT ANSWER>>>>Parenchymal cells (such as the liver or brain)
Anemia will lead to impaired energy production by the cell because there is:
1) Insufficient oxygen
2) Low glucose levels
3) Enzyme inhibition - CORRECT ANSWER>>>>Insufficient oxygen
Ischemia refers to:
1) A reduction of failure of blood supply to tissues
2) The death of tissues due to inadequate blood supply
3) Insufficient oxygenation of tissues due to poor blood supply - CORRECT
ANSWER>>>>A reduction of failure of blood supply to tissues
With vascular injury, platelets are exposed to the extracellular matrix, which induces
platelet adhesion via interaction with:
1) von Willebrand factor
2) Thromboxane
3) ADP - CORRECT ANSWER>>>>von Willebrand factor
The "economy class syndrome" occurs with prolonged air travel in cramped seating.
The described thrombosis occurs because there is:
2
, 1) Increased viscosity of blood due to poor oxygenation
2) Increased turbulence of blood flow
3) Stasis of blood flow in veins of the legs - CORRECT ANSWER>>>>Stasis of blood flow
in veins of the legs
Transient arteriolar vasoconstriction in early hemostasis is primarily due to:
1) Local secretion of vasoconstrictors
2) Reflex neurogenic mechanisms
3) Platelet-derived factors - CORRECT ANSWER>>>>Reflux neurogenic mechanisms
Which of the following statements regarding thrombosis is false?
1) Thrombus formation is favoured by both dehydration and inactivity
2) Pre-existing vascular disease would predispose to the development of thrombosis
3) Taking aspirin increases the risk of thrombus formation - CORRECT
ANSWER>>>>Taking aspirin increases the risk of thrombus formation
Edema may be the result of:
1) Hypertension
2) Elevated plasma osmotic pressure
3) Loss of plasma protein (e.g. due to renal glomerular disease) - CORRECT
ANSWER>>>>Loss of plasma protein (e.g. due to renal glomerular disease)
The intrinsic clotting mechanism is initiated by:
1) Tissue factor
2) Activation of factor XII by surface contact
3) Thrombin conversion - CORRECT ANSWER>>>>Activation of factor XII by surface contact
Venous obstruction is generally less likely to cause tissue injury than arterial
obstruction because:
1) Veins are smaller than arteries
2) There is greater availability of collateral vessels in the venous system
3) Venous obstruction develops more slowly - CORRECT ANSWER>>>>There is
greater availability of collateral vessels in the venous system
A person or animal in right sided heart failure may show:
1) Pulmonary venous congestion
2) Pulmonary edema
3) Hepatic congestion - CORRECT ANSWER>>>>Hepatic congestion
A person or animal in left sided heart failure may show which of the following?
3
Answers
Death of cells in a living organism is termed:
1) Gangrene
2) Necrosis
3) Ischemia - CORRECT ANSWER>>>>Necrosis
Apoptosis refers to:
1) The internalization of material by a cell
2) Disintegration of tissues which occurs after death
3) Programmed cell death - CORRECT ANSWER>>>>Programmed cell death
A myocardial infarct is seen as a dry, well demarcated area of pale tissue. This would
be described as:
1) Coagulation necrosis
2) Caseation necrosis
3) An abscess - CORRECT ANSWER>>>>Coagulation necrosis
Free radicals can impair cell membrane function by causing:
1) Lesions in DNA
2) Lipid peroxidation
3) Protein cross-linking - CORRECT ANSWER>>>>Lipid peroxidation
Starvation can lead to the development of fatty liver.
True or false? - CORRECT ANSWER>>>>True
Regional tissue necrosis due to ischemia, followed by secondary bacterial infection defines:
1) Autolysis
2) Putrefaction
3) Gangrene - CORRECT ANSWER>>>>Gangrene
Hypoxia, leading to impaired energy production by the cell, may be caused by:
1) Anemia
1
,2) Low blood glucose levels
3) Inhibition of respiratory enzymes - CORRECT ANSWER>>>>Anemia
The primary change in hemolytic jaundice is:
1) Inadequate bilirubin excretion
2) Increased production of bilirubin
3) Serum accumulation of conjugated bilirubin - CORRECT
ANSWER>>>>Increased production of bilirubin
Bilirubin is:
1) Lipid soluble when conjugated
2) Water soluble when conjugated
3) Conjugated in the kidney for excretion in the urine - CORRECT
ANSWER>>>>Water soluble when conjugated
Cellular injury can result when bilirubin accumulates in:
1) Parenchymal cells (such as the liver or brain)
2) Connective tissue
3) Skin - CORRECT ANSWER>>>>Parenchymal cells (such as the liver or brain)
Anemia will lead to impaired energy production by the cell because there is:
1) Insufficient oxygen
2) Low glucose levels
3) Enzyme inhibition - CORRECT ANSWER>>>>Insufficient oxygen
Ischemia refers to:
1) A reduction of failure of blood supply to tissues
2) The death of tissues due to inadequate blood supply
3) Insufficient oxygenation of tissues due to poor blood supply - CORRECT
ANSWER>>>>A reduction of failure of blood supply to tissues
With vascular injury, platelets are exposed to the extracellular matrix, which induces
platelet adhesion via interaction with:
1) von Willebrand factor
2) Thromboxane
3) ADP - CORRECT ANSWER>>>>von Willebrand factor
The "economy class syndrome" occurs with prolonged air travel in cramped seating.
The described thrombosis occurs because there is:
2
, 1) Increased viscosity of blood due to poor oxygenation
2) Increased turbulence of blood flow
3) Stasis of blood flow in veins of the legs - CORRECT ANSWER>>>>Stasis of blood flow
in veins of the legs
Transient arteriolar vasoconstriction in early hemostasis is primarily due to:
1) Local secretion of vasoconstrictors
2) Reflex neurogenic mechanisms
3) Platelet-derived factors - CORRECT ANSWER>>>>Reflux neurogenic mechanisms
Which of the following statements regarding thrombosis is false?
1) Thrombus formation is favoured by both dehydration and inactivity
2) Pre-existing vascular disease would predispose to the development of thrombosis
3) Taking aspirin increases the risk of thrombus formation - CORRECT
ANSWER>>>>Taking aspirin increases the risk of thrombus formation
Edema may be the result of:
1) Hypertension
2) Elevated plasma osmotic pressure
3) Loss of plasma protein (e.g. due to renal glomerular disease) - CORRECT
ANSWER>>>>Loss of plasma protein (e.g. due to renal glomerular disease)
The intrinsic clotting mechanism is initiated by:
1) Tissue factor
2) Activation of factor XII by surface contact
3) Thrombin conversion - CORRECT ANSWER>>>>Activation of factor XII by surface contact
Venous obstruction is generally less likely to cause tissue injury than arterial
obstruction because:
1) Veins are smaller than arteries
2) There is greater availability of collateral vessels in the venous system
3) Venous obstruction develops more slowly - CORRECT ANSWER>>>>There is
greater availability of collateral vessels in the venous system
A person or animal in right sided heart failure may show:
1) Pulmonary venous congestion
2) Pulmonary edema
3) Hepatic congestion - CORRECT ANSWER>>>>Hepatic congestion
A person or animal in left sided heart failure may show which of the following?
3
