MSRA Exam Ques ons and answers | Updated RATED
A+ | 2026 | NEW
How much does NRT and varenicline (Champix) increase rate of smoking cessa on?
Doubles the rate of smoking cessa on compared to GP advice alone
Affect of smoking on fer lity
Reduces both male and female fer lity and can lead to early menopause
conversion disorder
loss of func on (eg paralysis, blindness) due to unconsciouys mechanisms and in the absence of
an organic cause
Delusional disorder - soma c type
Like hypochondriasis, but more fixed
Fac ous disorder
Individual deliberately produces symptoms for which they then seek medical a-en on.
cf. malingering, where pa ents just make up symptoms
When is menopause diagnosed?
A1er 12 months of amenorrhoea
Symptoms include: hot flushes, insomnia, weight gain, mood changes
Average age = 50
Pelvic inflammatory disease
Infec on and inflamma on of upper female genital tract
Classic pa ent is aged <25yo, mul ple sexual partners, lives in area of high STI prevalence
Most common organisms = N. gonnorhoea, Chlamydia
Symptoms include: discharge, postcoital bleeding, fever
CHADS-VASc score
Conges ve heart failure (1)
Hypertension (1)
A2ge > 75 (2)
, Diabetes Mellitus (1)
S2troke/TIA/Thromboembolism (2)
Vascular disease (1)
Age 65-74 (1)
Sex (female = 1)
*Max = 9, =>2 then give warfarin or NOAC
What is eGFR cutoff for using nitrofurantoin?
Nitrofurantoin is CI in adults with an eGFR<45
Guillain-Barre syndrome
Progressive, bilateral, scending weakness
Usually a1er campylobacter, or viral infec on
Mononeuri s mul plex
Neuropathy of one, or more peripheral or cranial nerve
Pa ents present with asymmetrical weakness evolving at different mes in different nerves
Myasthenia gravis
Key feature is fa guability - symptoms worse at the end of the day
Polymyosi s
Symmetrical proximal muscle weakness, with significant muscle tenderness
Grades of hypertensive re nopathy
I = arteriolar narrowing
II = arteriovenous nipping
III = microaneurysyms, dot an blot haemorrhages, flame haemorrhages, co-on wool spots, hard
exudate
IV = op c disc swelling
V = THERE IS NO GRADE V
Tumour markers - LDH
Tes cular germ cell tumours
Tumour markers - Alpha-fetoprotein
A+ | 2026 | NEW
How much does NRT and varenicline (Champix) increase rate of smoking cessa on?
Doubles the rate of smoking cessa on compared to GP advice alone
Affect of smoking on fer lity
Reduces both male and female fer lity and can lead to early menopause
conversion disorder
loss of func on (eg paralysis, blindness) due to unconsciouys mechanisms and in the absence of
an organic cause
Delusional disorder - soma c type
Like hypochondriasis, but more fixed
Fac ous disorder
Individual deliberately produces symptoms for which they then seek medical a-en on.
cf. malingering, where pa ents just make up symptoms
When is menopause diagnosed?
A1er 12 months of amenorrhoea
Symptoms include: hot flushes, insomnia, weight gain, mood changes
Average age = 50
Pelvic inflammatory disease
Infec on and inflamma on of upper female genital tract
Classic pa ent is aged <25yo, mul ple sexual partners, lives in area of high STI prevalence
Most common organisms = N. gonnorhoea, Chlamydia
Symptoms include: discharge, postcoital bleeding, fever
CHADS-VASc score
Conges ve heart failure (1)
Hypertension (1)
A2ge > 75 (2)
, Diabetes Mellitus (1)
S2troke/TIA/Thromboembolism (2)
Vascular disease (1)
Age 65-74 (1)
Sex (female = 1)
*Max = 9, =>2 then give warfarin or NOAC
What is eGFR cutoff for using nitrofurantoin?
Nitrofurantoin is CI in adults with an eGFR<45
Guillain-Barre syndrome
Progressive, bilateral, scending weakness
Usually a1er campylobacter, or viral infec on
Mononeuri s mul plex
Neuropathy of one, or more peripheral or cranial nerve
Pa ents present with asymmetrical weakness evolving at different mes in different nerves
Myasthenia gravis
Key feature is fa guability - symptoms worse at the end of the day
Polymyosi s
Symmetrical proximal muscle weakness, with significant muscle tenderness
Grades of hypertensive re nopathy
I = arteriolar narrowing
II = arteriovenous nipping
III = microaneurysyms, dot an blot haemorrhages, flame haemorrhages, co-on wool spots, hard
exudate
IV = op c disc swelling
V = THERE IS NO GRADE V
Tumour markers - LDH
Tes cular germ cell tumours
Tumour markers - Alpha-fetoprotein
