lOMoAR cPSD| 61371432
NR546 Weekly Quiz Review: Key Concepts from Exam Preps |
Complete study Solutions | 2026-2027 Updates | 100%
correct | Chamberlain
Weekly Quiz reviews from Peer Support
Week 1
• The amygdala is associated with anxiety and perception of odors.
• The hippocampus is involved in memory and anxiety. The amygdala is associated
with anxiety and perception of odors. The prefrontal cortex is associated with
executive function. The thalamus is associated with motor command processing
• The client’s cognitive status can result in an ethical concern if the client is unable to
self-determine care or is a danger to self or others. Ability to pay is not an ethical
issue.
• basal ganglia are a group of structures involved in voluntary motor movements.
Basal ganglia are also involved in cognition and emotion.
• Limbic system is associated with emotion and learning
• hippocampi are associated with long term memory
• Wernicke's area is associated with speech comprehension. Review activity
• the dorsolateral prefrontal cortex (DLPFC) is concerned with higher level functioning.
The VLPFC is involved with motor inhibition the IFG contains Broca's area which is
associated with speech production understanding grammar. Pliska Ch. 8
• the OFC is involved in decision making and social behavior with a focus on
punishment and rewards. The OFC inhibits and activates the amygdala and is
activated when a risk assessment is required. Some behaviors associated with the
OFC include sex, sugar, pain, social humiliation, money, rewards, fame, and
aggression. The amygdala will identify a threat and then the OFC will determine the
risk or benefit of an action based on past experience. Pliska Ch. 8, p.158
• At this time, 20 % of the world’s population is suffering from a neurologic and/or
psychiatric disorder.
Week 2
• G protein linked systems, one of the signal transduction cascades, pass the message
from a first receptor to a second messenger .
, lOMoAR cPSD| 61371432
• Glutamate is an excitatory neurotransmitter. (NEI glutamate video- the glutamate
sisters)
• CYP 3A4 is one of the 5 most important NT which include CYP 1A2, 2D6, 2C9, 2C19,
3A4. Dosing adjustments may be required. Stahl p. 46-51.
• Smoking induces CYP1A2. Stahl p.48
• partial agonist- drug does not fully activate receptors; antagonist- drug binds to
receptor but does not activate a response; inverse agonist- drug cause opposite
effect of the agonist ;agonist- ;agonistdrug binds to the receptor and activates a
biological response
• G protein Linked systems and ion channel linked cascades are triggered by
neurotransmitters. Stahl p. 11
• Propagation of an action potential to the axon terminal is mediated by voltage-
sensitive sodium channels. Influx of sodium through voltage-sensitive sodium
channels at the axon terminal leads to opening of voltage-sensitive calcium channels,
also at the axon terminal. Influx of calcium through the open voltage sensitive
calcium channels leads to docking of synaptic vesicles and secretion of
neurotransmitter into the synapse.
• Agonists cause ligand-gated ion channels to open more frequently.
• The communication between neurons at synapses is mediated by neurotransmitter
molecules and is therefore chemical. Stahl p. 6
• Transcription factors are proteins that bind to promoter sequences of DNA to turn
gene expression on and off.
• chemical neurotransmission is the foundation of psychopharmacology
Week 3
• Major current hypothesis for the cause of schizophrenia proposes that glutamate
activity at N-methyl-d-aspartate (NMDA) receptors is hypofunctional due to
abnormalities in the formation of glutamatergic NMDA synapses during
neurodevelopment. Stahl p. 107
• EPSs manifest when dopamine receptor occupancy within the basal ganglia reaches
approximately 80% as the dopamine-mediated inhibition of movement is now
disinhibited (Refer to pathophysiology and the basal ganglia model of
movement)Stahl p.133 . See figure 5-4
• Risperidone has the highest risk for galactorrhea. Review tuberofundiular pathway
Stahl p.95
• clozapine is documented to decrease risk of suicide in schizophrenic clients. Stahl p.
181
• "Aripiprazole is associated with the lowest risk weight gain.
• All pines are associated with weight gain. Though not associated with large weight
gain, lurasidone is not associated with less weight gain in the same way as
aripiprazole. Week 3 lecture "
• Haldol is a first-generation antipsychotic, which can cause a dystonic reaction.
NR546 Weekly Quiz Review: Key Concepts from Exam Preps |
Complete study Solutions | 2026-2027 Updates | 100%
correct | Chamberlain
Weekly Quiz reviews from Peer Support
Week 1
• The amygdala is associated with anxiety and perception of odors.
• The hippocampus is involved in memory and anxiety. The amygdala is associated
with anxiety and perception of odors. The prefrontal cortex is associated with
executive function. The thalamus is associated with motor command processing
• The client’s cognitive status can result in an ethical concern if the client is unable to
self-determine care or is a danger to self or others. Ability to pay is not an ethical
issue.
• basal ganglia are a group of structures involved in voluntary motor movements.
Basal ganglia are also involved in cognition and emotion.
• Limbic system is associated with emotion and learning
• hippocampi are associated with long term memory
• Wernicke's area is associated with speech comprehension. Review activity
• the dorsolateral prefrontal cortex (DLPFC) is concerned with higher level functioning.
The VLPFC is involved with motor inhibition the IFG contains Broca's area which is
associated with speech production understanding grammar. Pliska Ch. 8
• the OFC is involved in decision making and social behavior with a focus on
punishment and rewards. The OFC inhibits and activates the amygdala and is
activated when a risk assessment is required. Some behaviors associated with the
OFC include sex, sugar, pain, social humiliation, money, rewards, fame, and
aggression. The amygdala will identify a threat and then the OFC will determine the
risk or benefit of an action based on past experience. Pliska Ch. 8, p.158
• At this time, 20 % of the world’s population is suffering from a neurologic and/or
psychiatric disorder.
Week 2
• G protein linked systems, one of the signal transduction cascades, pass the message
from a first receptor to a second messenger .
, lOMoAR cPSD| 61371432
• Glutamate is an excitatory neurotransmitter. (NEI glutamate video- the glutamate
sisters)
• CYP 3A4 is one of the 5 most important NT which include CYP 1A2, 2D6, 2C9, 2C19,
3A4. Dosing adjustments may be required. Stahl p. 46-51.
• Smoking induces CYP1A2. Stahl p.48
• partial agonist- drug does not fully activate receptors; antagonist- drug binds to
receptor but does not activate a response; inverse agonist- drug cause opposite
effect of the agonist ;agonist- ;agonistdrug binds to the receptor and activates a
biological response
• G protein Linked systems and ion channel linked cascades are triggered by
neurotransmitters. Stahl p. 11
• Propagation of an action potential to the axon terminal is mediated by voltage-
sensitive sodium channels. Influx of sodium through voltage-sensitive sodium
channels at the axon terminal leads to opening of voltage-sensitive calcium channels,
also at the axon terminal. Influx of calcium through the open voltage sensitive
calcium channels leads to docking of synaptic vesicles and secretion of
neurotransmitter into the synapse.
• Agonists cause ligand-gated ion channels to open more frequently.
• The communication between neurons at synapses is mediated by neurotransmitter
molecules and is therefore chemical. Stahl p. 6
• Transcription factors are proteins that bind to promoter sequences of DNA to turn
gene expression on and off.
• chemical neurotransmission is the foundation of psychopharmacology
Week 3
• Major current hypothesis for the cause of schizophrenia proposes that glutamate
activity at N-methyl-d-aspartate (NMDA) receptors is hypofunctional due to
abnormalities in the formation of glutamatergic NMDA synapses during
neurodevelopment. Stahl p. 107
• EPSs manifest when dopamine receptor occupancy within the basal ganglia reaches
approximately 80% as the dopamine-mediated inhibition of movement is now
disinhibited (Refer to pathophysiology and the basal ganglia model of
movement)Stahl p.133 . See figure 5-4
• Risperidone has the highest risk for galactorrhea. Review tuberofundiular pathway
Stahl p.95
• clozapine is documented to decrease risk of suicide in schizophrenic clients. Stahl p.
181
• "Aripiprazole is associated with the lowest risk weight gain.
• All pines are associated with weight gain. Though not associated with large weight
gain, lurasidone is not associated with less weight gain in the same way as
aripiprazole. Week 3 lecture "
• Haldol is a first-generation antipsychotic, which can cause a dystonic reaction.
