PCB 3233
PCB 3233 Exam 2 Study Questions
with Correct Answers 2026 Graded A+
What are two cells that use receptors to distinguish between self and non-self
cells?
-Macrophages
-NK Cells
C3b is a ligand for
Macrophage CR1
CR3 & CR4
Recognize iC3b & other ligands including LPS
Lectins
Carbohydrates-binding proteins
ex: Mannose & glucose receptors
Scavenger Receptors
Prefer molecules that are negatively charged like nucleic acids, LPS.
Phagocytic Receptors
Bind directly to microbial surface components
What do surface receptors promote?
Phagocytosis
PRR's bind to
PAMPs on pathogens
Receptors that detect microbial products signal what?
-Macrophage activation
-Cytokine Secretion
Toll-Like Receptors (TLR)
PCB 3233
, PCB 3233
-10 receptors
-Has specificities for several microbial products
TLR-4
-Senses LPS
-Found on macrophages
What can LPS cause?
Septic Shock
What is LPS known for being?
Endotoxin
What is local accumulation of fluid accompanied by?
Swelling, redness, heat, & pain
What does increased dilation cause?
Reduced blood flow
Complement receptors 3&4 (Mac-1, CD11b, CD8) target what?
Bacteria & Fungi
CD14 binds to what?
-LPS
-Peptidoglycan
What does IL-8 (CXCL-8) do?
Attracts leukocytes (neutrophils) to the site of infection/damage
What are your proinflammatory cytokines?
-IL-1Beta
-IL-6
-CXCL8 (IL-8)
-IL-12
-TNF Alpha
What does TLR7 Recognize?
PCB 3233
PCB 3233 Exam 2 Study Questions
with Correct Answers 2026 Graded A+
What are two cells that use receptors to distinguish between self and non-self
cells?
-Macrophages
-NK Cells
C3b is a ligand for
Macrophage CR1
CR3 & CR4
Recognize iC3b & other ligands including LPS
Lectins
Carbohydrates-binding proteins
ex: Mannose & glucose receptors
Scavenger Receptors
Prefer molecules that are negatively charged like nucleic acids, LPS.
Phagocytic Receptors
Bind directly to microbial surface components
What do surface receptors promote?
Phagocytosis
PRR's bind to
PAMPs on pathogens
Receptors that detect microbial products signal what?
-Macrophage activation
-Cytokine Secretion
Toll-Like Receptors (TLR)
PCB 3233
, PCB 3233
-10 receptors
-Has specificities for several microbial products
TLR-4
-Senses LPS
-Found on macrophages
What can LPS cause?
Septic Shock
What is LPS known for being?
Endotoxin
What is local accumulation of fluid accompanied by?
Swelling, redness, heat, & pain
What does increased dilation cause?
Reduced blood flow
Complement receptors 3&4 (Mac-1, CD11b, CD8) target what?
Bacteria & Fungi
CD14 binds to what?
-LPS
-Peptidoglycan
What does IL-8 (CXCL-8) do?
Attracts leukocytes (neutrophils) to the site of infection/damage
What are your proinflammatory cytokines?
-IL-1Beta
-IL-6
-CXCL8 (IL-8)
-IL-12
-TNF Alpha
What does TLR7 Recognize?
PCB 3233
