\COMPLETE QUESTIONS AND CORRECT DETAILED
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Drug interactions: drug-drug
When 2 drugs compete for metabolizing enzymes
Drug interactions: food-drug
Grapefruit juice or leafy greens
Drug interactions: additive
1+1 = 2; both provide intended effect
,Drug interactions: antagonistic
1+1 = <2; less than desired effect of one or both drugs
Drug interactions: synergistic
1+1 = >2; sum total effect is greater than if given alone (i.e. lisinopril
+ HCTZ)
,Drug interactions: incompatibility
1+1 does not equal 2; two IV drugs given together causing
decomposition of one or both drugs
8 rights of medication administration
Patient
Medication
Dose Route
Time
Reason
Response
Documentation
Adverse reactions: pharmacologic
Extension of a drug's normal effect
, Adverse reactions: Allergic/hypersensitivity
Exaggerated immune response (i.e. mild itching to anaphylaxis)
Adverse reactions: idiosyncratic
Peculiar to the patient
Adverse reactions: drug reaction
Most complex, difficult to determine
Teratogenic effects
Causes birth defects
Mutagenic effects
Able to cause changes in genetic tissue