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ANCC Family Nurse Practitioner (FNP)
Exam 2025/2026 – Practice Questions with
Expert Rationales
Karposi Sarcoma
- correct answer-Characteristic purple areas on the nose in an HIV-
positive female. A type of cancer that can form in the skin, lymph
nodes, or other organs. The skin lesions are usually purple in color.
Malodorous single nare
- correct answer-Foreign body
Retinal Detachment
- correct answer-the retina separates from the layer underneath.
Symptoms include an increase in the number of floaters, flashes of
light, and worsening of the outer part of the visual field.
Adolescent with friable nasal turbinates
- correct answer-Cocaine use
Aphthous ulcer
- correct answer-a recurrent round or oval sore or ulcer inside the
mouth on an area where the skin is not tightly bound to the
underlying bone, such as on the inside of the lips and cheeks or
underneath the tongue. Aphthous ulcers can also affect the genitalia
in males and females.
GERD first line tx
- correct answer-h2 then ppi if doesnt work
Maxillary Sinusitis
- correct answer-Dental pain
Kasmaul Triangle
1
, 2
- correct answer-Anterior epitaxis
Roseola infantum
- correct answer-H. fever => small pink dots pink or raised body rash
=> arms
Acne Roscaca
- correct answer-"adult acne." most often in adults (30-50 years of
age). Unlike acne vulgaris, rosacea is devoid of blackheads and
characteristically does not resolve after puberty. Rosacea strikes both
sexes and potentially all ages. It tends to be more frequent in women
but more severe in men. It is very uncommon in children, and it is less
frequent in people with dark skin. Tx with Flagyl
AV Nicking
- correct answer-HTN, arteries crossing veins
Blepharitis - correct answer-commonly occurs when the tiny oil glands
of the inner eyelid become inflamed. It often occurs along with other
skin conditions or allergies.
Symptoms include red, itchy eyelids that may look greasy and crusted.
Dry eyes also are a symptom.
Treatments include cleaning the eyelids, antibiotic or steroid eye
drops and treating underlying conditions. However, blepharitis tends
to come back.
Hordelum
- correct answer
-Painful stye it hurts
chalazion - correct answer-Non painful lesion to eyelid
Cotton Wool - correct answer-Cotton wool spots are an abnormal
finding on funduscopic exam of the retina of the eye. They appear as
fluffy white patches on the retina. They are caused by damage to
2
, 3
nerve fibers and are a result of accumulations of axoplasmic material
within the nerve fiber layer. Systemic HTN, DM
Herpes Zoster - correct answer-Early signs of shingles include a
burning sensation or stabbing pain and tingling or itching on the skin.
After a few days, a rash or blisters appear usually on one side of the
body or face. When the rash is at its peak, symptoms can range from
mild itching to extreme and debilitating pain. Tx within 72 hours
Aclovir
Retinoblastoma (Rb) - correct answer-Absence of light reflex, it is a
rare form of cancer that rapidly develops from the immature cells of a
retina, the light-detecting tissue of the eye. It is the most common
primary malignant intraocular cancer in children, and it is almost
exclusively found in young children.
Seborrheic dermatitis (Dandruff) - correct answer-commonly involves
portions of the scalp, brows, mid-face, ears, mid-chest, and mid-back.
It is not unusual for it to affect the skin of infants and young children
where it often involves the scalp (cradle cap) and the diaper area.
Seborrheic dermatitis is also known as seborrhea.
Seborrheic Keratosis - correct answer-A seborrhoeic keratosis is a
harmless warty spot that appears during adult life as a common sign
of skin aging. ... Seborrhoeic keratosis (or seborrheic keratosis, using
American spelling) is also called SK, basal cell papilloma, senile wart,
brown wart or barnacle.
Cupping of disc - correct answer-Intracranial pressure
subconjunctival haemorrhage - correct answer-is bleeding
underneath the conjunctiva. It can occur after a sudden or severe
sneeze or cough, heavy lifting, straining, vomiting or even rubbing
one's eyes too roughly. It can also occur as a side effect of eye surgery
or blood thinners.
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, 4
The main symptom is a bright red patch in the eye that may spread
and then become green or yellow, much like a bruise. Usually it
disappears within two weeks.
In most cases, no treatment is required for this condition.
Sialolithiasis (also termed salivary calculi, or salivary stones) - correct
answer-A condition where a calcified mass or sialolith forms within a
salivary gland, usually in the duct of the submandibular gland (also
termed "Wharton's duct").
Honey Crusted lesions - correct answer-Impetigo is a bacterial
infection that involves the superficial skin.The most common
presentation is yellowish crusts on the face, arms, or legs.Less
commonly there may be large blisters which affect the groin or
armpits. The lesions may be painful or itchy. Fever is uncommon.
It is typically due to either Staphylococcus aureus or Streptococcus
pyogenes. Risk factors include attending day care, crowding, poor
nutrition, diabetes mellitus, contact sports, and breaks in the skin
such as from mosquito bites, eczema, scabies, or herpes. With
contact it can spread around or between people.Diagnosis is typically
based on the symptoms.
Prevention is by hand washing, avoiding people who are infected, and
cleaning injuries. Treatment is typically with antibiotic creams such as
mupirocin or fusidic acid. Antibiotics by mouth, such as cephalexin,
may be used if large areas are affected. Antibiotic-resistant forms
have been found.
Mild acne - correct answer-Skin wash retinol benzol
moderate acne - correct answer-retinol plus tetracylines oral abx
Retinol reaction - correct answer-decrease to 3 times a day
4
ANCC Family Nurse Practitioner (FNP)
Exam 2025/2026 – Practice Questions with
Expert Rationales
Karposi Sarcoma
- correct answer-Characteristic purple areas on the nose in an HIV-
positive female. A type of cancer that can form in the skin, lymph
nodes, or other organs. The skin lesions are usually purple in color.
Malodorous single nare
- correct answer-Foreign body
Retinal Detachment
- correct answer-the retina separates from the layer underneath.
Symptoms include an increase in the number of floaters, flashes of
light, and worsening of the outer part of the visual field.
Adolescent with friable nasal turbinates
- correct answer-Cocaine use
Aphthous ulcer
- correct answer-a recurrent round or oval sore or ulcer inside the
mouth on an area where the skin is not tightly bound to the
underlying bone, such as on the inside of the lips and cheeks or
underneath the tongue. Aphthous ulcers can also affect the genitalia
in males and females.
GERD first line tx
- correct answer-h2 then ppi if doesnt work
Maxillary Sinusitis
- correct answer-Dental pain
Kasmaul Triangle
1
, 2
- correct answer-Anterior epitaxis
Roseola infantum
- correct answer-H. fever => small pink dots pink or raised body rash
=> arms
Acne Roscaca
- correct answer-"adult acne." most often in adults (30-50 years of
age). Unlike acne vulgaris, rosacea is devoid of blackheads and
characteristically does not resolve after puberty. Rosacea strikes both
sexes and potentially all ages. It tends to be more frequent in women
but more severe in men. It is very uncommon in children, and it is less
frequent in people with dark skin. Tx with Flagyl
AV Nicking
- correct answer-HTN, arteries crossing veins
Blepharitis - correct answer-commonly occurs when the tiny oil glands
of the inner eyelid become inflamed. It often occurs along with other
skin conditions or allergies.
Symptoms include red, itchy eyelids that may look greasy and crusted.
Dry eyes also are a symptom.
Treatments include cleaning the eyelids, antibiotic or steroid eye
drops and treating underlying conditions. However, blepharitis tends
to come back.
Hordelum
- correct answer
-Painful stye it hurts
chalazion - correct answer-Non painful lesion to eyelid
Cotton Wool - correct answer-Cotton wool spots are an abnormal
finding on funduscopic exam of the retina of the eye. They appear as
fluffy white patches on the retina. They are caused by damage to
2
, 3
nerve fibers and are a result of accumulations of axoplasmic material
within the nerve fiber layer. Systemic HTN, DM
Herpes Zoster - correct answer-Early signs of shingles include a
burning sensation or stabbing pain and tingling or itching on the skin.
After a few days, a rash or blisters appear usually on one side of the
body or face. When the rash is at its peak, symptoms can range from
mild itching to extreme and debilitating pain. Tx within 72 hours
Aclovir
Retinoblastoma (Rb) - correct answer-Absence of light reflex, it is a
rare form of cancer that rapidly develops from the immature cells of a
retina, the light-detecting tissue of the eye. It is the most common
primary malignant intraocular cancer in children, and it is almost
exclusively found in young children.
Seborrheic dermatitis (Dandruff) - correct answer-commonly involves
portions of the scalp, brows, mid-face, ears, mid-chest, and mid-back.
It is not unusual for it to affect the skin of infants and young children
where it often involves the scalp (cradle cap) and the diaper area.
Seborrheic dermatitis is also known as seborrhea.
Seborrheic Keratosis - correct answer-A seborrhoeic keratosis is a
harmless warty spot that appears during adult life as a common sign
of skin aging. ... Seborrhoeic keratosis (or seborrheic keratosis, using
American spelling) is also called SK, basal cell papilloma, senile wart,
brown wart or barnacle.
Cupping of disc - correct answer-Intracranial pressure
subconjunctival haemorrhage - correct answer-is bleeding
underneath the conjunctiva. It can occur after a sudden or severe
sneeze or cough, heavy lifting, straining, vomiting or even rubbing
one's eyes too roughly. It can also occur as a side effect of eye surgery
or blood thinners.
3
, 4
The main symptom is a bright red patch in the eye that may spread
and then become green or yellow, much like a bruise. Usually it
disappears within two weeks.
In most cases, no treatment is required for this condition.
Sialolithiasis (also termed salivary calculi, or salivary stones) - correct
answer-A condition where a calcified mass or sialolith forms within a
salivary gland, usually in the duct of the submandibular gland (also
termed "Wharton's duct").
Honey Crusted lesions - correct answer-Impetigo is a bacterial
infection that involves the superficial skin.The most common
presentation is yellowish crusts on the face, arms, or legs.Less
commonly there may be large blisters which affect the groin or
armpits. The lesions may be painful or itchy. Fever is uncommon.
It is typically due to either Staphylococcus aureus or Streptococcus
pyogenes. Risk factors include attending day care, crowding, poor
nutrition, diabetes mellitus, contact sports, and breaks in the skin
such as from mosquito bites, eczema, scabies, or herpes. With
contact it can spread around or between people.Diagnosis is typically
based on the symptoms.
Prevention is by hand washing, avoiding people who are infected, and
cleaning injuries. Treatment is typically with antibiotic creams such as
mupirocin or fusidic acid. Antibiotics by mouth, such as cephalexin,
may be used if large areas are affected. Antibiotic-resistant forms
have been found.
Mild acne - correct answer-Skin wash retinol benzol
moderate acne - correct answer-retinol plus tetracylines oral abx
Retinol reaction - correct answer-decrease to 3 times a day
4
