BIO 325 Final Exam Review Questions With
Correct Answers
Ribosomal |genes |are |transcribed |by |RNA |Polymerase |___ |- |CORRECT |ANSWER✔✔-I
In |Prokaryotes, |cluster |of |genes |can |be |regulated |together. |This |cluster |of |genes |is |called |an |
____ |- |CORRECT |ANSWER✔✔-operon
E. |coli's |heat |shock |response |is |controlled |by |alternative |______ |factors |that |recognize |
different |promoter |sequences. |- |CORRECT |ANSWER✔✔-sigma
"Certain |covalent |modifications |of |Histone |can |dictate |the |fate |of |gene |expression |at |given |
loci" |is |referred |as |_____ |_____ |hypothesis. |- |CORRECT |ANSWER✔✔-Histone |Code
p53 |can |induce |programmed |cell |death |if |the |damage |cannot |be |repaired |through |a |process |
called |______ |. |- |CORRECT |ANSWER✔✔-apoptosis
Generally |speaking, |cancer |is |due |to |abnormal |or |uncontrolled |_____ |division |- |CORRECT |
ANSWER✔✔-cell
XXY |male |would |have |____ |Barr |body(ies) |- |CORRECT |ANSWER✔✔-1
In |an |old |view |of |heredity, |__________ |inheritance |assumes |that |parental |traits |become |
mixed |and |forever |changed |in |offspring. |- |CORRECT |ANSWER✔✔-blending
A |short |single-stranded |piece |of |DNA |that |is |labeled |and |used |in |hybridization |experiments |is |
called |a(n) |________ |- |CORRECT |ANSWER✔✔-probe
,T/F: |Genotype |frequency |can |change |until |the |population |comes |to |equilibrium. |- |CORRECT |
ANSWER✔✔-True
T/F: |Trimethylation |at |Histone |H3 |Lys |27 |usually |associated |with |transcriptionally |repressed |
chromatins |- |CORRECT |ANSWER✔✔-True
T/F: |After |meiosis |I, |chromosome |set |number |is |n. |- |CORRECT |ANSWER✔✔-True
T/F: |High |concentration |of |Glucose |is |necessary |for |the |maximum |induction |of |Lac |operon |
genes. |- |CORRECT |ANSWER✔✔-False
T/F: |A |man |with |blood |type |"A," |whose |father |was |blood |type |"O," |married |a |woman |of |blood
|type |"B" |whose |mother |was |blood |type |"O." |Children |of |this |couple |can |have |all |possible |
blood |types |- |CORRECT |ANSWER✔✔-True
T/F: |HIV |contains |reverse |transcriptase. |- |CORRECT |ANSWER✔✔-True
T/F: |cDNAs |from |eukaryotic |organisms |contain |promoter |region. |- |CORRECT |ANSWER✔✔-False
T/F: |The |map |of |a |chromosome |interval |is |A--10 |m.u.--B-- |40 |m.u.--C. |From |the |cross |Abc/aBC |
× |abc/abc, |you |observed |10 |double |crossovers |from |1000 |progeny. |In |this |case, |interference |is |
0.5 |- |CORRECT |ANSWER✔✔-False
T/F: |Population |at |Hardy-Weinberg |equilibrium |assumes |that |there |is |no |new |mutation |over |
generations. |- |CORRECT |ANSWER✔✔-True
T/F: |Nimblegen |array |uses |photo-activating |building |blocks |to |construct |DNA |array |on |the |
slide. |- |CORRECT |ANSWER✔✔-True
,If |grandparents |are |heterozygous |for |the |trait, |what |is |the |probability |that |a |child |in |question |
would |NOT |have |the |trait |(disease).
A. |1/4
B. |3/4
C. |1/3
D. |2/3 |- |CORRECT |ANSWER✔✔-D |(2/3)
What |technique |would |be |used |to |best |study |a |phenocopy?
A. |RNAi
B. |Transgene
C. |Isolation |of |mutations
D. |QTL |mapping |analysis
E. |Microarray |- |CORRECT |ANSWER✔✔-A |(RNAi)
In |eukaryotes, |transcriptional |activity |is |low |when:
A. |DNA |is |hypermethylated.
B. |Histone |is |hyperacetylated.
C. |Histone |H3 |Lys |4 |is |methylated. |D. |Histone |H3 |Lys |36 |is |methylated |E. |none |of |the |above. |- |
CORRECT |ANSWER✔✔-A |(DNA |is |hypermethylated)
Which |of |the |following |is |property |of |Enhancer?
A. |it |is |one |of |tran-acting |components |in |gene |regulation. |B. |it |is |always |located |immediate |5' |
end |of |a |gene.
C. |it |is |always |located |immediate |3' |end |of |a |gene.
D. |its |orientation |is |not |important. |- |CORRECT |ANSWER✔✔-D |(its |orientation |is |not |important)
, The |Rb |activity |is |regulated |by
A. |its |phosphorylation |state. |
B. |its |methylation |level |
C. |cyclin |A. |
D. |E2F |
E. |its |polyA |tail. |- |CORRECT |ANSWER✔✔-A |(its |phosphorylation |state)
In |humans, |brachydactyly |is |a |dominant |condition. |Six |thousand |four |hundred |people |in |a |
population |of |10,000 |show |the |disease |(1,600 |are |BB, |4,800 |are |Bb) |and |3,600 |are |normal |
phenotypes |(bb). |The |frequency |of |the |b |allele |is
A. |0.6 |
B. |0.4 |
C. |0.36 |
D. |0.48 |
E. |0.16 |- |CORRECT |ANSWER✔✔-A |(0.6)
A |codon |is |a |three |base |sequence |of
A. |mRNA |that |codes |for |an |amino |acid.
B. |rRNA |that |codes |for |an |amino |acid. |
C. |tRNA |that |codes |for |an |amino |acid. |
D. |DNA |that |codes |for |an |amino |acid. |- |CORRECT |ANSWER✔✔-A |(mRNA |that |codes |for |an |
amino |acid)
Which |of |the |following |is |NOT |involved |in |RNA |interference |processes?
A. |RISC
B. |Drosha
C. |RNA |Polymerase |I
Correct Answers
Ribosomal |genes |are |transcribed |by |RNA |Polymerase |___ |- |CORRECT |ANSWER✔✔-I
In |Prokaryotes, |cluster |of |genes |can |be |regulated |together. |This |cluster |of |genes |is |called |an |
____ |- |CORRECT |ANSWER✔✔-operon
E. |coli's |heat |shock |response |is |controlled |by |alternative |______ |factors |that |recognize |
different |promoter |sequences. |- |CORRECT |ANSWER✔✔-sigma
"Certain |covalent |modifications |of |Histone |can |dictate |the |fate |of |gene |expression |at |given |
loci" |is |referred |as |_____ |_____ |hypothesis. |- |CORRECT |ANSWER✔✔-Histone |Code
p53 |can |induce |programmed |cell |death |if |the |damage |cannot |be |repaired |through |a |process |
called |______ |. |- |CORRECT |ANSWER✔✔-apoptosis
Generally |speaking, |cancer |is |due |to |abnormal |or |uncontrolled |_____ |division |- |CORRECT |
ANSWER✔✔-cell
XXY |male |would |have |____ |Barr |body(ies) |- |CORRECT |ANSWER✔✔-1
In |an |old |view |of |heredity, |__________ |inheritance |assumes |that |parental |traits |become |
mixed |and |forever |changed |in |offspring. |- |CORRECT |ANSWER✔✔-blending
A |short |single-stranded |piece |of |DNA |that |is |labeled |and |used |in |hybridization |experiments |is |
called |a(n) |________ |- |CORRECT |ANSWER✔✔-probe
,T/F: |Genotype |frequency |can |change |until |the |population |comes |to |equilibrium. |- |CORRECT |
ANSWER✔✔-True
T/F: |Trimethylation |at |Histone |H3 |Lys |27 |usually |associated |with |transcriptionally |repressed |
chromatins |- |CORRECT |ANSWER✔✔-True
T/F: |After |meiosis |I, |chromosome |set |number |is |n. |- |CORRECT |ANSWER✔✔-True
T/F: |High |concentration |of |Glucose |is |necessary |for |the |maximum |induction |of |Lac |operon |
genes. |- |CORRECT |ANSWER✔✔-False
T/F: |A |man |with |blood |type |"A," |whose |father |was |blood |type |"O," |married |a |woman |of |blood
|type |"B" |whose |mother |was |blood |type |"O." |Children |of |this |couple |can |have |all |possible |
blood |types |- |CORRECT |ANSWER✔✔-True
T/F: |HIV |contains |reverse |transcriptase. |- |CORRECT |ANSWER✔✔-True
T/F: |cDNAs |from |eukaryotic |organisms |contain |promoter |region. |- |CORRECT |ANSWER✔✔-False
T/F: |The |map |of |a |chromosome |interval |is |A--10 |m.u.--B-- |40 |m.u.--C. |From |the |cross |Abc/aBC |
× |abc/abc, |you |observed |10 |double |crossovers |from |1000 |progeny. |In |this |case, |interference |is |
0.5 |- |CORRECT |ANSWER✔✔-False
T/F: |Population |at |Hardy-Weinberg |equilibrium |assumes |that |there |is |no |new |mutation |over |
generations. |- |CORRECT |ANSWER✔✔-True
T/F: |Nimblegen |array |uses |photo-activating |building |blocks |to |construct |DNA |array |on |the |
slide. |- |CORRECT |ANSWER✔✔-True
,If |grandparents |are |heterozygous |for |the |trait, |what |is |the |probability |that |a |child |in |question |
would |NOT |have |the |trait |(disease).
A. |1/4
B. |3/4
C. |1/3
D. |2/3 |- |CORRECT |ANSWER✔✔-D |(2/3)
What |technique |would |be |used |to |best |study |a |phenocopy?
A. |RNAi
B. |Transgene
C. |Isolation |of |mutations
D. |QTL |mapping |analysis
E. |Microarray |- |CORRECT |ANSWER✔✔-A |(RNAi)
In |eukaryotes, |transcriptional |activity |is |low |when:
A. |DNA |is |hypermethylated.
B. |Histone |is |hyperacetylated.
C. |Histone |H3 |Lys |4 |is |methylated. |D. |Histone |H3 |Lys |36 |is |methylated |E. |none |of |the |above. |- |
CORRECT |ANSWER✔✔-A |(DNA |is |hypermethylated)
Which |of |the |following |is |property |of |Enhancer?
A. |it |is |one |of |tran-acting |components |in |gene |regulation. |B. |it |is |always |located |immediate |5' |
end |of |a |gene.
C. |it |is |always |located |immediate |3' |end |of |a |gene.
D. |its |orientation |is |not |important. |- |CORRECT |ANSWER✔✔-D |(its |orientation |is |not |important)
, The |Rb |activity |is |regulated |by
A. |its |phosphorylation |state. |
B. |its |methylation |level |
C. |cyclin |A. |
D. |E2F |
E. |its |polyA |tail. |- |CORRECT |ANSWER✔✔-A |(its |phosphorylation |state)
In |humans, |brachydactyly |is |a |dominant |condition. |Six |thousand |four |hundred |people |in |a |
population |of |10,000 |show |the |disease |(1,600 |are |BB, |4,800 |are |Bb) |and |3,600 |are |normal |
phenotypes |(bb). |The |frequency |of |the |b |allele |is
A. |0.6 |
B. |0.4 |
C. |0.36 |
D. |0.48 |
E. |0.16 |- |CORRECT |ANSWER✔✔-A |(0.6)
A |codon |is |a |three |base |sequence |of
A. |mRNA |that |codes |for |an |amino |acid.
B. |rRNA |that |codes |for |an |amino |acid. |
C. |tRNA |that |codes |for |an |amino |acid. |
D. |DNA |that |codes |for |an |amino |acid. |- |CORRECT |ANSWER✔✔-A |(mRNA |that |codes |for |an |
amino |acid)
Which |of |the |following |is |NOT |involved |in |RNA |interference |processes?
A. |RISC
B. |Drosha
C. |RNA |Polymerase |I
