Exam 2. dr. Wunderlich
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symptoms of conductive hearing loss - correct answer diminished hearing, speaking in a SOFT
voice, individual can hear better in a noisy environment (paracusia willisiana)
causes of conductive hearing loss - correct answer impacted cerumen, foreign bodies, benign
tumor of middle ear
sensorineural hearing loss - correct answer caused by impairment of the organ of Corti or its
central connections. Can possibly be congenital; conditions include noise exposure, aging,
meniere disease, ototoxicity
presbycusis - correct answer age-related hearing loss usually in high frequencies. progression is
slow and onset of symptoms is gradual
glaucoma - correct answer leading cause of visual impairment and blindness; family history is a
risk factor, can be inheritied
,open angle - correct answer most common type of glaucoma
purpose of the inflammatory process - correct answer the inflammatory process is the body's
second line of defense when epithelial barrier is damaged. It's purpose is to limit the extent of
damage, protect against infection, and initiate repair of the damaged tissue
what are the 4 cardinal signs of inflammation - correct answer edema, pain, warmth, and
redness
edema: arterioles near the site of infection or injury constrict briefly. Vasodilation then causes
slower blood velocity and increases local blood flow to the injured site. plasma leaks from
vessels to tissues causing swelling and blood becomes more viscous
warmth/redness: the increased blood flow and increasing concentration of red cells at the site
of inflammation. leukocytes adhere to vessel walls
pain: biochemical mediators, such as histamine, stimulate the endothelial cells that line
capillaries and venules to retract, creating spaces at junction between cells
chemotactic factor - correct answer a biochemical substance that attracts leukocytes to the site
of inflammation
describe chemotactic activity - correct answer this activity occurs distal to the inflammation in
order to attract leukocytes from circulation. this activity is required for a much longer period
than that of anaphylatoxic activity
phagocytosis - correct answer the destruction of microorganisms and cellular debris; the
process by which a cell ingests and disposes of damaged cells and foreign material
describe the action of phagocytes in inflammation - correct answer 1. opsonization (recognition
of the target and adherence of the phagocyte to it
2. engulfment (ingestion or endocytosis) and formation of phagosome
3. fusion with lysosomal granules within the phagocyte (phagolysosome)
, 4. destruction of the target
what systemic changes are associated with acute inflammation - correct answer fever,
leukocytosis ( transient increase in the number of circulating leukocytes), and plasma proteins
how can fever be beneficial - correct answer the generation of a febrile response can be
beneficial because the microorganisms that cause some conditions are highly sensitive to small
increases in body temp
resolution of tissue - correct answer is damage is minor, no complications occur, and destroyed
tissues are capable of regeneration, it is possible to return injured tissues to an approximation
of their original structure and physiologic function
repair of tissue - correct answer replacement of destroyed tissue with scar tissue; new tissue
may not be able to function as the original tissue; occurs if resolution is not possible
what happens if resolution is not possible - correct answer repair takes place instead. This is
when extensive damage is present, injury occurs in tissues not capable of regeneration,
infection results in abscess or granuloma formation, or fibrin persists in the lesion; scar tissue
forms
what population is at risk for impaired inflammation and wound healing - correct answer older
adults; impaired healing may not be directly associated with again but can be linked to a chronic
illness such as heart disease or DM. In addition, anti-inflammatory steroid medications can
interfere with the healing process
humoral immunity - correct answer antibody circulates in the blood and binds to antigens on
infectious agents
cellular immunity - correct answer T cells undergo differentiation during an immune response
and develop into several subpopulations of cells that react directly with antigen on the surface