ONS ONCC CHEMOTHERAPY IMMUNOTHERAPY
CERTIFICATION LATEST 170 EXAM QUESTIONS 2026 2027
ONCOLOGY NURSING REVIEW CHEMOTHERAPY AND
IMMUNOTHERAPY PRINCIPLES VERIFIED QUESTIONS
WITH ACCURATE ANSWERS UPDATED 2026 2027 COURSE
FINAL COMPLETE PRACTICE QUESTIONS AND LATEST
UPDATED STUDY GUIDE HIGH-YIELD COMPLETE TEST
BANK GRADED A+ 100 PERCENT VERIFIED
Adaptive immunity leads to what? - CORRECT ANSWER -immune system memory
related to a pathogen or foreign substance
What are the three parts of adaptive immunity? - CORRECT ANSWER humoral
immunity, cell mediated immunity, regulatory t-cells
What is humoral immunity made up of? - CORRECT ANSWER -b lymphocytes, memory
b cells, and plasma to produce immunoglobulins or antibodies
What is cell mediated immunity dependent on? - CORRECT ANSWER -
cytotoxic t-cells, helper t-cells and their cytokines
What are regulatory t-cells also known as? - CORRECT ANSWER -supressor t-cells
What do regulatory t-cells do? - CORRECT ANSWER -regulate the immune response to
prevent autoimmune reactions and limit inflammatory responses
What are cytokines? - CORRECT ANSWER -cytokines are secreted by lymphocytes
with the intention of stimulating macrophages and cytotoxic t lymphocytes to identify and
kill pathogen infected cells or tumor cells What do proto-oncogenes do? - CORRECT
ANSWER -regulate normal cell growth and division.
,What are proto-oncogenes? - CORRECT ANSWER -they are a large family of genes
that code for proteins and enzymes that turn on the cell cycle
If a mistake in copies of DNA occur next to a porto-oncogene, it can "turn on" and
become what? - CORRECT ANSWER -oncogene
What are two examples of an oncogene? - CORRECT ANSWER -EGFR/Erb- B1 and
Erb-B2/HER2
What is a very important tumor suppressor gene? - CORRECT ANSWER p53
What is the p53 gene also called? - CORRECT ANSWER -suicide gene
What does neoadjuvant therapy refer to? - CORRECT ANSWER -treatment given as a
first step to shrink a tumor before the main treatment
What is adjuvant therapy? - CORRECT ANSWER -additional cancer treatment given
after the primary treatment to lower the risk that cancer will occur
How do alkylating agents function? - CORRECT ANSWER -by causing a break in the
DNA helix strand, causing interference with DNA replication, which results in cell death
What are the three most common alkylating agent chemo's? - CORRECT
ANSWER -cytoxan, ifos, bendamustine
How are alkylating agents and platinum based chemo's different? - CORRECT
ANSWER -platinum based chemo's do not have the molecule to to attach to and destroy
DNA
What are the two most common platinum based chemo's? - CORRECT
,ANSWER -cisplatin and carboplatin
What should you instruct patients to do when receiving oxaliplatin? - CORRECT
ANSWER -to avoid exposure to cold air and consuming cold fluids for 3 to 4 days
following treatment
What are the two most nephrotoxic drugs? - CORRECT ANSWER streptozocin and
semustine
What are the most common side effects of antimetabolites? - CORRECT ANSWER -
myelosuppresion, GI toxicities, photosensitivity, hand foot syndrome,
What kind of chemo therapy require life time doses? - CORRECT ANSWER antitumor
antibiotics
What are examples of anthracyclines that? - CORRECT ANSWER doxorubicin,
daunarubicin, epirubicin, idarubicin
What are lifetime doses needed for anthrcyclines? - CORRECT ANSWER cardiotoxicity
What are classes of antitumor antibiotics? - CORRECT ANSWER anthracyclines and
non-anthracyclines
What are examples of non-anthracyclines? - CORRECT ANSWER actinomycin d,
mitomycin c, bleomycin
Why is there a lifetime dose for bleomycin? - CORRECT ANSWER pulmonary fibrosis
Patient's with what diagnosis are more at risk for anaphylaxis to bleomycin? -
CORRECT ANSWER -lymphoma
, How to calculate an ANC - CORRECT ANSWER -(%polys or segs + %bands) x
WBC/100
What are common plant alkaloids? - CORRECT ANSWER -etoposide, docetaxol,
paclitaxel, vinblastine, vinorelbine
Lesson 1: Foundations to Set the Stage - CORRECT ANSWER -
Focusing on Cellular Structure and Function - CORRECT ANSWER -
The Normal Cell Cycle - CORRECT ANSWER --The cell cycle refers to the ordered
seres of processes of DNA replication and mitosis, or cell division
-Cell nucleus regulates these processes by gathering and processing complexes
molecular information
Interphase and Mitotic Phase - CORRECT ANSWER -Cell division produces two
identical cells through these two major phases
During interphase: - CORRECT ANSWER -Cell grows and DNA is replicated through the
following three steps:
1: First growth phase (G1 or first gap)
2: Synthesis phase (S phase)
3:Mitotic Phse (M phase)
First Growth Phase (G1 or first gap) - CORRECT ANSWER --cells increase in size
-reproduce RNA
CERTIFICATION LATEST 170 EXAM QUESTIONS 2026 2027
ONCOLOGY NURSING REVIEW CHEMOTHERAPY AND
IMMUNOTHERAPY PRINCIPLES VERIFIED QUESTIONS
WITH ACCURATE ANSWERS UPDATED 2026 2027 COURSE
FINAL COMPLETE PRACTICE QUESTIONS AND LATEST
UPDATED STUDY GUIDE HIGH-YIELD COMPLETE TEST
BANK GRADED A+ 100 PERCENT VERIFIED
Adaptive immunity leads to what? - CORRECT ANSWER -immune system memory
related to a pathogen or foreign substance
What are the three parts of adaptive immunity? - CORRECT ANSWER humoral
immunity, cell mediated immunity, regulatory t-cells
What is humoral immunity made up of? - CORRECT ANSWER -b lymphocytes, memory
b cells, and plasma to produce immunoglobulins or antibodies
What is cell mediated immunity dependent on? - CORRECT ANSWER -
cytotoxic t-cells, helper t-cells and their cytokines
What are regulatory t-cells also known as? - CORRECT ANSWER -supressor t-cells
What do regulatory t-cells do? - CORRECT ANSWER -regulate the immune response to
prevent autoimmune reactions and limit inflammatory responses
What are cytokines? - CORRECT ANSWER -cytokines are secreted by lymphocytes
with the intention of stimulating macrophages and cytotoxic t lymphocytes to identify and
kill pathogen infected cells or tumor cells What do proto-oncogenes do? - CORRECT
ANSWER -regulate normal cell growth and division.
,What are proto-oncogenes? - CORRECT ANSWER -they are a large family of genes
that code for proteins and enzymes that turn on the cell cycle
If a mistake in copies of DNA occur next to a porto-oncogene, it can "turn on" and
become what? - CORRECT ANSWER -oncogene
What are two examples of an oncogene? - CORRECT ANSWER -EGFR/Erb- B1 and
Erb-B2/HER2
What is a very important tumor suppressor gene? - CORRECT ANSWER p53
What is the p53 gene also called? - CORRECT ANSWER -suicide gene
What does neoadjuvant therapy refer to? - CORRECT ANSWER -treatment given as a
first step to shrink a tumor before the main treatment
What is adjuvant therapy? - CORRECT ANSWER -additional cancer treatment given
after the primary treatment to lower the risk that cancer will occur
How do alkylating agents function? - CORRECT ANSWER -by causing a break in the
DNA helix strand, causing interference with DNA replication, which results in cell death
What are the three most common alkylating agent chemo's? - CORRECT
ANSWER -cytoxan, ifos, bendamustine
How are alkylating agents and platinum based chemo's different? - CORRECT
ANSWER -platinum based chemo's do not have the molecule to to attach to and destroy
DNA
What are the two most common platinum based chemo's? - CORRECT
,ANSWER -cisplatin and carboplatin
What should you instruct patients to do when receiving oxaliplatin? - CORRECT
ANSWER -to avoid exposure to cold air and consuming cold fluids for 3 to 4 days
following treatment
What are the two most nephrotoxic drugs? - CORRECT ANSWER streptozocin and
semustine
What are the most common side effects of antimetabolites? - CORRECT ANSWER -
myelosuppresion, GI toxicities, photosensitivity, hand foot syndrome,
What kind of chemo therapy require life time doses? - CORRECT ANSWER antitumor
antibiotics
What are examples of anthracyclines that? - CORRECT ANSWER doxorubicin,
daunarubicin, epirubicin, idarubicin
What are lifetime doses needed for anthrcyclines? - CORRECT ANSWER cardiotoxicity
What are classes of antitumor antibiotics? - CORRECT ANSWER anthracyclines and
non-anthracyclines
What are examples of non-anthracyclines? - CORRECT ANSWER actinomycin d,
mitomycin c, bleomycin
Why is there a lifetime dose for bleomycin? - CORRECT ANSWER pulmonary fibrosis
Patient's with what diagnosis are more at risk for anaphylaxis to bleomycin? -
CORRECT ANSWER -lymphoma
, How to calculate an ANC - CORRECT ANSWER -(%polys or segs + %bands) x
WBC/100
What are common plant alkaloids? - CORRECT ANSWER -etoposide, docetaxol,
paclitaxel, vinblastine, vinorelbine
Lesson 1: Foundations to Set the Stage - CORRECT ANSWER -
Focusing on Cellular Structure and Function - CORRECT ANSWER -
The Normal Cell Cycle - CORRECT ANSWER --The cell cycle refers to the ordered
seres of processes of DNA replication and mitosis, or cell division
-Cell nucleus regulates these processes by gathering and processing complexes
molecular information
Interphase and Mitotic Phase - CORRECT ANSWER -Cell division produces two
identical cells through these two major phases
During interphase: - CORRECT ANSWER -Cell grows and DNA is replicated through the
following three steps:
1: First growth phase (G1 or first gap)
2: Synthesis phase (S phase)
3:Mitotic Phse (M phase)
First Growth Phase (G1 or first gap) - CORRECT ANSWER --cells increase in size
-reproduce RNA
