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Pharma B manual EXAM QUESTIONS AND VERIFIED CORRECT ANSWERS

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Pharma B manual EXAM QUESTIONS AND VERIFIED CORRECT ANSWERS Pharma B manual EXAM QUESTIONS AND VERIFIED CORRECT ANSWERS

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D. Cefepime All of the following are third generation cephalosporins EXCEPT?
A. Ceftriaxone
B. Cefotaxime
C. Ceftazidime
D. Cefepime


C. Methicillin Which of the following is an example of B-lactamase resistant narrow spectrum
antibiotic?
A. Penicillin
B. Amoxicillin
C. Methicillin
D. Piperacillin


b) penicillin g What is the drug of choice for syphilis infection?
A. Amoxicillin
B. Penicillin G
C. Nafcillin
D. Piperacillin


A. Methicillin Which of the following is primarily used for susceptible staphylococcal
infections?
A. Methicillin
C. Ampicillin
B. Penicillin V
D. Amoxicillin


Vancomycin What is the drug of choice for Methicillin-resistant staphylococci (MRSA)?
A. Meropenem
B. Aztreonam
C. Vancomycin
D. Fosfomycin

,A. 1st generation Which among the following cephalosporins mostly covers Gram (+) cocci?
A. 1st generation
B. 2nd generation
C. 3rd generation
D. 4th generation


B. 2nd generation Cefaclor is an example of what generation cephalosporin?
A. 1st generation
B. 2nd generation
C. 3rd generation
D. 4th generation


D. Cefipime Which among the following cephalosporins combines the gram (+) activity of the
1st generation
drugs with the gram (-) activity of the 3rd generation drugs?
A. Cefazolin
B. Cefotetan
C. Cefixime
D. Cefipime


C. Cefixime All of the following 3rd generation cephalosporins can penetrate the BBB
EXCEPT?
A. Ceftazidime
C. Cefixime
B. Ceftriaxone
D. Cefotaxime


A. Ertapenem All of the following carbapenems have anti-pseudomonal coverage EXCEPT?
A. Ertapenem
C. Imipenem
B. Meropenem
D. Doripenem


Interfering with the formation of initiation complexes and Clindamycin inhibits bacterial protein synthesis by:
aminoacyl translocation reactions A. Inhibiting DNA gyrase
B. C. Interfering with the formation of initiation complexes and aminoacyl
translocation reactions
Blocking the 30S ribosomal subunit
D. Inhibiting peptidoglycan synthesis


The 30S ribosomal subunit Aminoglycosides inhibit protein synthesis by binding to:
A. The 50S ribosomal subunit
B. The 30S ribosomal subunit
C. DNA polymerase
D. RNA polymerase


Calcium gluconate or neostigmine A curare-like effect with neuromuscular blockade caused by aminoglycosides can
be reversed by:
A. Furosemide or bumetanide
B. Calcium gluconate or neostigmine
C. Amphotericin or vancomycin
D. Beta-lactam antibiotics

, Neomycin, kanamycin, and amikacin Which aminoglycosides are most likely to cause auditory damage?
A. Streptomycin and gentamicin
B. Neomycin, kanamycin, and amikacin
C. Neomycin, tobramycin, and gentamicin
D. Plazomicin and streptomycin


Deafness in the newborn What is a potential adverse effect of streptomycin use during pregnancy?
A. Neonatal jaundice
B. Congenital heart defects
C. Deafness in the newborn
D. Neural tube defects


Binding to the 50S ribosomal subunit and inhibition of What is the mechanism of action of chloramphenicol?
peptide bond formation A. Inhibition of DNA synthesis
B. Binding to the 50S ribosomal subunit and inhibition of peptide bond formation
C. Disruption of bacterial cell wall synthesis
D. Inhibition of folate synthesis


Production of chloramphenicol acetyltransferase What is the primary mechanism of clinically significant resistance to
chloramphenicol?
A. Reduced permeability to the drug
B. Mutation of the 50S ribosomal subunit
C. Production of chloramphenicol acetyltransferase
D. Efflux pump activity


. Food decreases absorption significantly, requiring What is the clinical significance of food interactions with tetracyclines like
administration at specific times relative to meals omadacycline?
A. Absorption is unaffected by food or cations.
B. Food enhances the absorption of omadacycline.
C. Food decreases absorption significantly, requiring administration at specific
times relative to meals
D. Dairy products improve the bioavailability of omadacycline


Binding to the 50S ribosomal RNA to inhibit protein What is the primary mechanism of action of erythromycin?
synthesis A. Inhibition of DNA gyrase
B. Binding to the 50S ribosomal RNA to inhibit protein synthesis
C. Disruption of the bacterial cell wall
D. Inhibition of folic acid synthesis


It is free of drug interactions involving cytochrome P450 What is a significant advantage of azithromycin compared to erythromycin and
enzymes clarithromycin?
A. It inhibits cytochrome P450 enzymes.
B. It has no impact on potassium channels.
C. It is free of drug interactions involving cytochrome P450 enzymes
D. It is active against all gram-negative bacteria


Rapid growth of mycobacteria Which of the following is NOT a challenge in chemotherapy for mycobacterial
infections?
A. Development of drug resistance
B. Chronic nature of infections requiring prolonged treatment
C. Rapid growth of mycobacteria
D. High risk of drug-related toxicities

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