TEST 2026 QUESTIONS WITH SOLUTIONS
GRADED A+
>> Cats
Answer: Which animal is an obligate carnivore, cats or dogs?
>> Chronic
Answer: Is it more common in dogs to get acute or chronic hepatitis?
>> 4 months
Answer: How long do liver enzymes have to be elevated associated with inflammation for it to be
considered chronic hepatitis?
>> 3. regeneration
Answer: Canine chronic hepatitis is a SYNDROME, meaning it is multifactorial. List the causes
>> Cirrhosis
Answer: If chronic hepatitis goes on long enough, there is diffuse bridging fibrosis in the liver. What is
this called?
>> Shunts --> eventually lead to ascites
Answer: With canine chronic hepatitis, scar tissue can lead to portal hypertension. How does the body
get around this?
>> Idiopathic (which we assume is immune mediated)
Answer: What is the most common cause of canine chronic hepatitis?
>> Hyperbilirubinemia, coagulopathy, ascites
Answer: How does liver failure clinically present in dogs?
>> Absent until disease is ADVANCED
Answer: Clinical symptoms are absent until WHAT POINT in chronic canine hepatitis?
>> Female spayed middle aged dog (6-8ish yo). Bedlingtons (cannot metabolize copper), Labs,
Dobermans. Chronic ALT elevation.
Answer: What is the basic signalment that puts animals at the top of the list for developing chronic
hepatitis in dogs?
>> ALT and AST
, Answer: Chronic canine hepatitis is an inflammatory condition. This means the liver cells get angry
with hepatocellular damage and dump WHAT enzymes?
>> Chronic portal hypertension that leads to acquired portosystemic shunting to relieve pressure -->
causes "triad" of clinical signs = ascites, GI ulceration (bleeding), hepatic encephalopathy
Answer: What is the pathogenesis that leads to chronic idiopathic hepatitis?
>> Ascites, GI ulceration (bleeding), hepatic encephalopathy
Answer: What is the clinical "triad" of end stage cirrhosis?
>> 75-80% of function is lost
Answer: Clinical signs do not appear until HOW MUCH of liver function is lost in chronic hepatitis?
>> Chronic ALT elevation
Answer: What is the most consistent bloodwork finding for canine chronic hepatitis?
>> There are not enough healthy cells left to leak and mount an elevated response
Answer: Hepatocellular enzymes can normalize towards end stage liver disease WHY?
>> Lumpy, irregularly marginated scar tissue liver that is small probably with ascites
Answer: If an animal is in end stage with cirrhosis of the liver, what will the liver itself look like?
>> Biopsy = full thickness to determine architexture = MULTIPLE SAMPLES (want 12-15 portal triads
in the samples)
Answer: What is the KEY diagnostic for canine chronic idiopathic hepatitis?
>> 5. prevent complications
Answer: What are the BROAD pillars of treatment for canine chronic hepatitis?
>> note: use should be LIMITED and based on biopsy results, immunosuppressive doses should
NOT be used chronically
Answer: What is the big drug used for immunosuppressive therapy for canine idiopathic chronic
hepatitis?
>> 10. Diuretics for ascites (Spironolactone)
Answer: What are more specific treatments for canine chronic hepatitis?
>> Spironolactone
Answer: What is the initial choice for ascites treatment for aldosterone inhibition in patients with
chronic hepatitis?
>> f. choleretic (Ursodeoxycholic)