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NURS 497 MIDTERM 2 2026 REAL
QUESTIONS WITH EXPERTLY
VERIFIED ANSWERS.
Clinical manifestations of hemochromatosis - correct answer -
fatigue, malaise, abdominal pain, arthralgias, impotence, clinical
findings of hepatomegaly, abnormal liver enzymes, bronzed skin,
diabetes, and cardiomegaly
Clinical manifestations of juvenile hemochromatosis in females -
correct answer -fail to start menstrual cycle at proper age, has
erratic periods or stops having period once she began
Clinical manifestation of juvenile hemochromatosis in males -
correct answer -hypogonadism
Sickle cell trait - correct answer -- most common form of sickle
cell disease
- heterozygous condition
- child is carrier of sickle cell anemia and rarely has symptoms of
the disease
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Sickle cell anemia - correct answer -- homozygous condition
- child is subject to sickle cell crises
Sickle cells disorders - correct answer -a hereditary condition
where there is a replacement of normal hemoglobin with
abnormal hemoglobin S in rbcs
- kids <5yrs have greater risk
Sickle turbidity test - correct answer -- perform a finger stick as a
component
- if test is positive, hemoglobin electrophoresis is required to
distinguish if child has trait
- quick screening for children >6months once fetal hgb falls
Hgb electrophoresis - correct answer -identifies
hemoglobinopathies (sickle cell anemia and thalassemia)
"fingerprinting" of the protein
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Sickle cell anemia clinical manifestations - correct answer -- may
be triggered by fever and emotional stress
- manifested by sickle cell crises
- acute chest syndrome (fever, chest pain, progressive respiratory
distress, increased WBC count, pulmonary infiltrates)
- cerebrovascular accident (stroke)
- infection
- priapism
Vaso-occlusive thrombotic crises - correct answer -- caused by
stasis of blood with clumping of cells in microcirculation leading to
ischemia and later infarction
Symptoms of vaso-occlusive thrombotic crises - correct answer -
fever, pain, tissue engorgement
Splenic sequestration - correct answer -caused by pooling of
blood in the spleen leading to splenomegaly
Signs of splenic sequestration - correct answer -profound anemia,
hypovolemia, shock
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Complications of splenomegaly - correct answer -- may become
so full of blood, that it becomes fragile and vulnerable to trauma
- splenic rupture
- changes in CV function due to rupture
Aplastic crises - correct answer -dimished production and
increased destruction of rbcs, triggered by viral infection or
depletion of folic acid; can cause avascular necrosis in hip and
shoulder which can lead to loss of function
Signs of aplastic crises - correct answer -profound anemia, pallor,
fatigue
Factor VIII - correct answer -antihemophilic factor; cofactor for
intrinsic activation of factor X; congenital deficiency is hemophilia
A
Factor IX - correct answer -christmas factor; activated form is
enzyme for intrinsic activation of factor X; congenital deficiency is
hemophilia B
NURS 497 MIDTERM 2 2026 REAL
QUESTIONS WITH EXPERTLY
VERIFIED ANSWERS.
Clinical manifestations of hemochromatosis - correct answer -
fatigue, malaise, abdominal pain, arthralgias, impotence, clinical
findings of hepatomegaly, abnormal liver enzymes, bronzed skin,
diabetes, and cardiomegaly
Clinical manifestations of juvenile hemochromatosis in females -
correct answer -fail to start menstrual cycle at proper age, has
erratic periods or stops having period once she began
Clinical manifestation of juvenile hemochromatosis in males -
correct answer -hypogonadism
Sickle cell trait - correct answer -- most common form of sickle
cell disease
- heterozygous condition
- child is carrier of sickle cell anemia and rarely has symptoms of
the disease
, Page | 2
Sickle cell anemia - correct answer -- homozygous condition
- child is subject to sickle cell crises
Sickle cells disorders - correct answer -a hereditary condition
where there is a replacement of normal hemoglobin with
abnormal hemoglobin S in rbcs
- kids <5yrs have greater risk
Sickle turbidity test - correct answer -- perform a finger stick as a
component
- if test is positive, hemoglobin electrophoresis is required to
distinguish if child has trait
- quick screening for children >6months once fetal hgb falls
Hgb electrophoresis - correct answer -identifies
hemoglobinopathies (sickle cell anemia and thalassemia)
"fingerprinting" of the protein
, Page | 3
Sickle cell anemia clinical manifestations - correct answer -- may
be triggered by fever and emotional stress
- manifested by sickle cell crises
- acute chest syndrome (fever, chest pain, progressive respiratory
distress, increased WBC count, pulmonary infiltrates)
- cerebrovascular accident (stroke)
- infection
- priapism
Vaso-occlusive thrombotic crises - correct answer -- caused by
stasis of blood with clumping of cells in microcirculation leading to
ischemia and later infarction
Symptoms of vaso-occlusive thrombotic crises - correct answer -
fever, pain, tissue engorgement
Splenic sequestration - correct answer -caused by pooling of
blood in the spleen leading to splenomegaly
Signs of splenic sequestration - correct answer -profound anemia,
hypovolemia, shock
, Page | 4
Complications of splenomegaly - correct answer -- may become
so full of blood, that it becomes fragile and vulnerable to trauma
- splenic rupture
- changes in CV function due to rupture
Aplastic crises - correct answer -dimished production and
increased destruction of rbcs, triggered by viral infection or
depletion of folic acid; can cause avascular necrosis in hip and
shoulder which can lead to loss of function
Signs of aplastic crises - correct answer -profound anemia, pallor,
fatigue
Factor VIII - correct answer -antihemophilic factor; cofactor for
intrinsic activation of factor X; congenital deficiency is hemophilia
A
Factor IX - correct answer -christmas factor; activated form is
enzyme for intrinsic activation of factor X; congenital deficiency is
hemophilia B
