SOLUTIONS|UPDATED A+ SCORE VERSION 2026
Beta blockers
Worsen insulin resistance and decrease glucose uptake,
increasing triglycerides
Amylin
Deficient in type 1 dm
Ketones
Present in type 1 dm
Diabetes drugs not lowering bg
Biguanide, dpp4 inhibitors, glp1 agonists, alpha-glucosidase
inhibitors
Dpp4 inhibitor
Sitagliptin, known as 'gliptins'
Diabetes drugs lowering bg
,Sglt2 inhibitors, sulfonylureas
Sglt2 inhibitors
Canagliflozin, dapagliflozin, empagliflozin
Dka warning
A1c x 3 - 6, add a 0: glucose average over 3 months
B12 deficiency anemia
Macrocytic. Patients will have neurological issues. Elevated
methylmalonic acid and homocysteine
Primary thyroid disorders
Dysfunction of the thyroid gland
Effects of hypothyroidism
Increased cholesterol & weight gain. Puts patient at risk for
cardiovascular disease
Untreated hypothyroidism
, Myxedema coma and b12/folate deficiency anemia
Endemic goiter
Results from dietary iodine deficiency
Subclinical hypothyroidism
Elevated tsh + normal t3 + t4
Primary hypothyroidism
Elevated tsh, low t3 and t4
Myxedema coma
Extreme hypothyroidism (abrupt medication cessation), rare
with a high mortality rate = decreased cardiac output leads to
decreased tissue perfusion which leads to brain and organ
depletion leading to multi-organ failure
Treatment for manic symptoms in dementia
Divalproex sodium (depakote) 1st, or carbamazepine,
lamotrigine, lithium