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• Neurulation
• Cell proliferation
What are the 5 steps of neurological development in or-
• Migration and aggregation
der?
• Formation of axonal and dendritic processes
• Synaptogenesis
Neurulation
______________ involves the formation of the neural
crest and neural tube.
Cell proliferation occurs within the ________ _______. Neural tube
During the migration and aggregation phase of embry-
ological development the cells migrate/aggregate within Definitive
_________ locations.
• Formation of axonal and dendritic processes
4th stage in embryological development
• Development of CN
True or false:
Cranial nerves are formed during the formation of axonal
True
and dendritic processes phase of embryological develop-
ment.
____________ occurs around day 14 of development. Neurulation
During __________ the embryo is in the process of gas-
Neurulation
trolation.
The __________ is three cell layers thick and includes the
Gastrula (Day 14)
ectoderm, mesoderm, and endoderm.
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The entire nervous system is derived from the
Embryonic ectoderm
____________ ___________.
On day _____ the notochord develops followed by the
21, 28
neural tube on day _______.
The _______ ________ develops into the the entire CNS. Neural tube
Neuroectoderm portion of the ectoderm that becomes the nervous system
Neural crest cells develop into the ______. PNS
a system of fluid-filled cavities inside the brain
Ventricular system
Cavity within neural tube
• Spina bifida (failure of POSTERIOR neuropore to close)
What two pathologies can occur during the first stage of
• Anencephaly (failure of the ANTERIOR neuropore to
embryological development?
close)
Neurulation
STAGE 1: Embryological Development
-fibers of sensory and motor neurons (somatic/autonom-
Nerves (PNS)
ic)
defect in closure of the cephalic portion of the neural tube
Anencephaly
that results in incomplete development of the brain and
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bones of the skull; the most drastic neural tube defect
usually results in a stillbirth
• Prosencephalon(forebrain)
• Mesencephalon (midbrain)
• Rhombencephalon (hindbrain)
• Primitive Neural Tube (Spinal Cord)
4 divisions of Embryological development
• Telencephalon
• Diencephalon
Prosencephalon(forebrain): Subdivision
Telencephalon:
• Rhinencephalon
Diencephalon:
• Thalamus
• Hypothalamus
Prosencephalon(forebrain): Derivatives
• Optic Nerves
• Neurohypophysis
• Pineal Gland
Prosencephalon(forebrain): Cavities