Glycolys s
STAGE 1 13step
MMMGlucose
of
Phosphorylat on
Cumununu Stept
bIHzott opuzo t POİ
ATP u ı ADP
oHN bu
T
o Htt µOH
OH OH
atGlucose become morepolar traps ns dethecell
Increases ts
energy more react ve morel kelyto undergoglycolys s
Note Hexok nase l keall Prote n k nases depends onthe presence ofa d valentmetalatomsu nas
Mg or Mna
allwater molecules aregone bytheact onof hexok nase because
watermoleculesare very nto ATPandmake t hydrolyse
İ
ÇIĞ femat ngen nat t
Isomer zat on step 2
mumcu H Ö H _CHzo t
c c
ı ı
H c OH H c OH
ı 03 o Ö CHzo t
a OH_c µ C H
1,0
oy
H d OH H d OH
H d OH H d OH OH
1
CHzopojz CHzopojz
The enzyme phosphoglucose somerase transforms analdose nto ketose
mumun
Second Phosphorylat on step3
humunu
ATP A Phospho k
OHIO OHIO occurs
1 1 muchmore nstobk
OH OH
Fructose 6 phosphate Fructose 1.6phosphate
i
, STAGE 2
Breakdown
mummy 1,6 B
ofmumumu
Fructose phosphate
e
step 4
Anenzymecalled aldolase catalyzesthebreakdownthestructure
ntotwo d fferent threecarbonmolecules glyceraldehyde 3phosphate
andd hydroxyacetone phosphate DHAPI
_cazopoz 2
2030g özopojz _cazopoz p dolase
OH
l a 1
H_c OH
Iıı I
Cycl cfructose 1,6phoshale
H c OH
ı ı
H c OH H c OH
cHzPO cHzPO
opencha n
The glyceraldehyde l esd rectly onthe glycolyt c pathway tcongod rectlyto STAGE3
So DHAP should bemod f ed to GAP
JSOFERAFONTFDHAPtoGR.PT
Step5
umumunu
Anenzyme called tr ose phosphate somerase TPI orTIM catalyzes therap dand
revers ble
DHAPto GAP
convers on
of
c
CHz POİ µ ne
ı
Hz POİ convers on
v a an
ofthe ketose ntoanaldose
redoxreact on n
ntramolecular
H H H H wh ch a H stronferredfrom KI to C2
f Ç
H
GAP In 4.1
DHAP 1.961
0o
nerde
Th s enzyme stops a compet ng react onfrom
ocur ng
Ha OH o
C c
H l opojz H
s.tl oPojz
Hz
H H
Howedon'twant th s react on
a
STAGE 1 13step
MMMGlucose
of
Phosphorylat on
Cumununu Stept
bIHzott opuzo t POİ
ATP u ı ADP
oHN bu
T
o Htt µOH
OH OH
atGlucose become morepolar traps ns dethecell
Increases ts
energy more react ve morel kelyto undergoglycolys s
Note Hexok nase l keall Prote n k nases depends onthe presence ofa d valentmetalatomsu nas
Mg or Mna
allwater molecules aregone bytheact onof hexok nase because
watermoleculesare very nto ATPandmake t hydrolyse
İ
ÇIĞ femat ngen nat t
Isomer zat on step 2
mumcu H Ö H _CHzo t
c c
ı ı
H c OH H c OH
ı 03 o Ö CHzo t
a OH_c µ C H
1,0
oy
H d OH H d OH
H d OH H d OH OH
1
CHzopojz CHzopojz
The enzyme phosphoglucose somerase transforms analdose nto ketose
mumun
Second Phosphorylat on step3
humunu
ATP A Phospho k
OHIO OHIO occurs
1 1 muchmore nstobk
OH OH
Fructose 6 phosphate Fructose 1.6phosphate
i
, STAGE 2
Breakdown
mummy 1,6 B
ofmumumu
Fructose phosphate
e
step 4
Anenzymecalled aldolase catalyzesthebreakdownthestructure
ntotwo d fferent threecarbonmolecules glyceraldehyde 3phosphate
andd hydroxyacetone phosphate DHAPI
_cazopoz 2
2030g özopojz _cazopoz p dolase
OH
l a 1
H_c OH
Iıı I
Cycl cfructose 1,6phoshale
H c OH
ı ı
H c OH H c OH
cHzPO cHzPO
opencha n
The glyceraldehyde l esd rectly onthe glycolyt c pathway tcongod rectlyto STAGE3
So DHAP should bemod f ed to GAP
JSOFERAFONTFDHAPtoGR.PT
Step5
umumunu
Anenzyme called tr ose phosphate somerase TPI orTIM catalyzes therap dand
revers ble
DHAPto GAP
convers on
of
c
CHz POİ µ ne
ı
Hz POİ convers on
v a an
ofthe ketose ntoanaldose
redoxreact on n
ntramolecular
H H H H wh ch a H stronferredfrom KI to C2
f Ç
H
GAP In 4.1
DHAP 1.961
0o
nerde
Th s enzyme stops a compet ng react onfrom
ocur ng
Ha OH o
C c
H l opojz H
s.tl oPojz
Hz
H H
Howedon'twant th s react on
a
