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enzymes summary

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B ochem stry 11_ ENZYMES

Prote ns actsas catalyst to accelerate a react on d ver homogenate Icatatese enzyme
and not permanently changed ntheprocess G Oxygenbubbles occur

D glucose Glucose ox dase
Glucondactone Hydrogen perox de substrate


www.eeaewamaea esfo.ae Iş Ta cp.o.ws
ofthe free glucose
determ nat on d fferent products occur
two act ve s desHor Ozegluca
products glucanoloctore tl202 enzyme donat changeafterthe
react on
Enzymes arevery select ve molecules
substrate
jo ns theact ve s de oftheenzyme
mutual reeognot on occur spec f c ty
restr ctedreg on act ves de
nameofthe substrate
Nam ng the enzymes or ase
the typeofthereact on
Spec f c ty
tw llonly beableto catalyse part cularreact on

Bond 1 Ox doreductases elect ons
Substrate 2 Transferases grouptransfers


1
S
pp üssünü
Geometr cal 5 Isomers somer cforms
G factor 6 l gases 1 condensat onreact ons


E6112
lower ng act vat on energy
enzyme
enzymes
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commun ty
eco.gea.org

w thoutenzyme

ümüğünü. r
jje
aa oa. onan.gy
for
trans t on state occur everyenzyme
Tl ncreas ngratemeansthat concentrat on of productsaresome
product on
Max Maxproduct generat on

Act ve s te substrate b nds
lys neh st d ne cyste ne ser n ty os n arer ch
Yact
Electroph l c
ve
groups canbefoordattle
s de
n act ve s tes ofthe enzymes Mg Un Fe NH




i i

, Lock and KeyModel The key s analog andalsosubstrate
Product havea d fferent shape fromthesubstrate
spec f c complementary geometr c shape
t fa lsthe stab l zat onofthetrans t on
statethatenzymes


Induced F t Moda
Character st cs


enzymes relax ble prote ns change the r conformat on
reshap ngoccur enzyme conformat on
b
çemokaka
s
rangeof substrates
of s m lar types
E 5 Es product


enzymes Cofactors regeneralty
Cofactors norgan c or organ c
Apoenzyme
Iyseotrspeusfsubst od .to
o
oenzyme regenerated concentrat on staysthe same
enzymes r boflav n th am nefol cac d
pnet mes coenzyme A acetylgroupcarr es Ht
Conjugated Enzyme structure
need both coenzyme cofactor
T Enoughand qual f ed foodntake s mportant
Substrate concentrat on
for enzyme react on
Temperature Factorseffect ng cofactor andcoenzyme
pH enzymes
Inh b tors


Substrate Concentrat on proport onal
Zateofreat on

enzymesconstant Between A B notall act ves tesoccup ed
Rmax
MD enzyme react ons substrateconcentrat on
Nyon


1 3 S
donat ncrease becauseall enzymes
are used8 5c
anyfurther
not us nganydrug or healthy l fe

More enzymes can reactw th
1 n
more substrate molecules




i

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