STUDY GUIDE
f r The
ATI
Comprehensive
Predictor
2026/2027
by
N CLEX GUIDE TO 85
ww w. Nu rsing Persp e ctiv e. com
, ATI Comprehensive Predictor Study Guide
Table of Contents
Lab Values 4
Lab Tests 6
ABGs 7
Community Nursing 8
Fundamentals of Nursing 9
Nursing Considerations in the Hospital 10
Prioritization 12
Duties and Delegation 12
Death and Dying 13
Safety and Infection Control 14
Transmission-Based Precautions 15
Fire Safety 16
Nursing Considerations 16
Disaster Triage 18
Leadership 19
Quality of Care 19
Disciplinary and Intervening 19
Interprofessional Team and Effective Collaboration 19
Legal Responsibilities 19
Client Advocacy 20
Medical Surgical Nursing 21
Cardiovascular 21
Heart Arrhythmias 22
Endocrine 26
Diabetes Mellitus 27
Electrolytes 29
Gastrointestinal 31
Hematologic, Immune System, and Cancer 34
Cancer 36
Integumentary System 38
Peripheral Vascular Disorders 40
Musculoskeletal System 41
Neurosensory System 44
Cranial nerves 46
Renal 50
Respiratory 53
Must-Know Clinical Signs 56
Patient Positioning 58
STIs 60
Maternity 61
2
, Signs of Pregnancy 62
Pregnancy Complications 62
Fetal Heart Rate Monitoring 63
Labor and Delivery 64
Postpartum Assessment 67
Newborn Assessment 69
Diagnostic Tests 71
Nursing Considerations 72
Nutrition 73
Diets 73
Nursing Considerations 74
Pediatrics 76
Pediatric Congenital Defects 80
Pediatric System Disorders 80
Communicable Diseases 83
Immunizations 84
Pediatric Nursing Considerations 84
Poisoning 86
Child Abuse 86
Mental Health 88
Effective Communication 89
Mental Health Disorders 90
Substance Abuse 94
Psych Medications 95
Pharmacology 98
Common drug class suffixes 98
Food-Medication Interactions 98
Nursing Considerations 99
Medications to Know 100
Medications Requiring Frequent Monitoring 103
Complementary and Alternative Therapies 105
Test-Taking Strategies 108
3
, Lab Values
RBCs Females: 4.7-6.1 Elevated level: Severe dehydration, polycythemia vera, erythrocytosis
million Decreased level: Anemia, kidney disease, hemorrhage
Males: 4.2-5.4 million
WBCs 5,000-10,000 Elevated level: Inflammation, infection
Decreased level: Immunosuppression, autoimmune disease
HGB Females: 12-16 A protein in red blood cells that carries oxygen.
Males: 14-18 Elevated level: COPD, erythrocytosis,, severe dehydration
Decreased level: Anemia, kidney disease, hemorrhage
HCT Females: 37%-47% Same as above for Hgb.
Measures the percentage of red blood cells in blood.
Males: 42%-52%
Elevated level: Erythrocytosis, COPD, severe dehydration
Decreased level: Anemia, kidney disease, hemorrhage
PLTs 150,000-400,000 If the patient is receiving a Heparin infusion and their platelets drop lower than
100,000, STOP the infusion first.
- Antidote for Heparin is Protamine.
Elevated level: Malignancy, polycythemia vera, rheumatoid arthritis
Decreased level: Enlarged spleen, leukemia, hemorrhage
PT 11-12.5 seconds Evaluate the extrinsic system and common pathway in a clotting mechanism.
Anticoagulation 1.5-2 Used to assess patients on warfarin, their levels will be one to two times higher
than normal.
Critical: >20
Increased time: Warfarin therapy, disseminated intravascular coagulation (DIC),
clotting factors II, V, VII, or X, liver disease
Decreased time: Vitamin K excess, thrombophlebitis, pulmonary embolus
4
f r The
ATI
Comprehensive
Predictor
2026/2027
by
N CLEX GUIDE TO 85
ww w. Nu rsing Persp e ctiv e. com
, ATI Comprehensive Predictor Study Guide
Table of Contents
Lab Values 4
Lab Tests 6
ABGs 7
Community Nursing 8
Fundamentals of Nursing 9
Nursing Considerations in the Hospital 10
Prioritization 12
Duties and Delegation 12
Death and Dying 13
Safety and Infection Control 14
Transmission-Based Precautions 15
Fire Safety 16
Nursing Considerations 16
Disaster Triage 18
Leadership 19
Quality of Care 19
Disciplinary and Intervening 19
Interprofessional Team and Effective Collaboration 19
Legal Responsibilities 19
Client Advocacy 20
Medical Surgical Nursing 21
Cardiovascular 21
Heart Arrhythmias 22
Endocrine 26
Diabetes Mellitus 27
Electrolytes 29
Gastrointestinal 31
Hematologic, Immune System, and Cancer 34
Cancer 36
Integumentary System 38
Peripheral Vascular Disorders 40
Musculoskeletal System 41
Neurosensory System 44
Cranial nerves 46
Renal 50
Respiratory 53
Must-Know Clinical Signs 56
Patient Positioning 58
STIs 60
Maternity 61
2
, Signs of Pregnancy 62
Pregnancy Complications 62
Fetal Heart Rate Monitoring 63
Labor and Delivery 64
Postpartum Assessment 67
Newborn Assessment 69
Diagnostic Tests 71
Nursing Considerations 72
Nutrition 73
Diets 73
Nursing Considerations 74
Pediatrics 76
Pediatric Congenital Defects 80
Pediatric System Disorders 80
Communicable Diseases 83
Immunizations 84
Pediatric Nursing Considerations 84
Poisoning 86
Child Abuse 86
Mental Health 88
Effective Communication 89
Mental Health Disorders 90
Substance Abuse 94
Psych Medications 95
Pharmacology 98
Common drug class suffixes 98
Food-Medication Interactions 98
Nursing Considerations 99
Medications to Know 100
Medications Requiring Frequent Monitoring 103
Complementary and Alternative Therapies 105
Test-Taking Strategies 108
3
, Lab Values
RBCs Females: 4.7-6.1 Elevated level: Severe dehydration, polycythemia vera, erythrocytosis
million Decreased level: Anemia, kidney disease, hemorrhage
Males: 4.2-5.4 million
WBCs 5,000-10,000 Elevated level: Inflammation, infection
Decreased level: Immunosuppression, autoimmune disease
HGB Females: 12-16 A protein in red blood cells that carries oxygen.
Males: 14-18 Elevated level: COPD, erythrocytosis,, severe dehydration
Decreased level: Anemia, kidney disease, hemorrhage
HCT Females: 37%-47% Same as above for Hgb.
Measures the percentage of red blood cells in blood.
Males: 42%-52%
Elevated level: Erythrocytosis, COPD, severe dehydration
Decreased level: Anemia, kidney disease, hemorrhage
PLTs 150,000-400,000 If the patient is receiving a Heparin infusion and their platelets drop lower than
100,000, STOP the infusion first.
- Antidote for Heparin is Protamine.
Elevated level: Malignancy, polycythemia vera, rheumatoid arthritis
Decreased level: Enlarged spleen, leukemia, hemorrhage
PT 11-12.5 seconds Evaluate the extrinsic system and common pathway in a clotting mechanism.
Anticoagulation 1.5-2 Used to assess patients on warfarin, their levels will be one to two times higher
than normal.
Critical: >20
Increased time: Warfarin therapy, disseminated intravascular coagulation (DIC),
clotting factors II, V, VII, or X, liver disease
Decreased time: Vitamin K excess, thrombophlebitis, pulmonary embolus
4
