PHAR1101 EEMCQ - FAMOUS DISCOVERERS EXAM QUESTIONS AND AN- SWERS
1. Tu Youyou discovered artemisinin while spearheading project 523
2. John Cade discovered lithium, saw relaxation ettects on rats injected w uric acid dissolve in
lithium salt
3. Gertrude Elion, discovered many drugs that were analogues of the purine and pyrimidine bases
George Hitchings present in nucleic acids such as DNA and RNA; developed mercaptopurine for
treating childhood leukaemia
4. Miguel Onedetti discovered first gen ACEI (lowers BP) by isolating snake venom
5. Nagai Nagayoshi isolated l-ephedrine from ephedra while working in berlin
6. Sachahiro Hata, developed animal model of syphillis by infecting rabbits w t. pallidum spirochetes
Paul Ehrlich -> discovered arsphenamine and marketed as salvarsan
7. John Vane, Sergio found that snake venom strongly blocked the enzyme ACE, thereby preventing the
Ferrereira conversion of Angiotensin I into the blood pressure raising peptide Angiotensin II
8. Dorothy Hodgkin used X-ray crystallography to crack the 4-membered ring structure of penicillin
9. Ernst Chain A fugitive from the Nazis who extracted penicillin from mould
10. Marcel Janbon head of montplier med school, studying a number of sulfanilamide analogues,
seeking a drug to treat the typhus infections
11. Klaus Fuchs rediscovered the sugar-lowering properties of sulfanilamide analogues; injected
and experienced hypoglycaemic ettects himself
12. Akiro Endo discovered lovastatin simultaneously w researches from beecham pharmaceuticals
13. Friedrich W. Ser- isolated poppy seeds and confirmed sleep-inducing ettects in dogs
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1. Tu Youyou discovered artemisinin while spearheading project 523
2. John Cade discovered lithium, saw relaxation ettects on rats injected w uric acid dissolve in
lithium salt
3. Gertrude Elion, discovered many drugs that were analogues of the purine and pyrimidine bases
George Hitchings present in nucleic acids such as DNA and RNA; developed mercaptopurine for
treating childhood leukaemia
4. Miguel Onedetti discovered first gen ACEI (lowers BP) by isolating snake venom
5. Nagai Nagayoshi isolated l-ephedrine from ephedra while working in berlin
6. Sachahiro Hata, developed animal model of syphillis by infecting rabbits w t. pallidum spirochetes
Paul Ehrlich -> discovered arsphenamine and marketed as salvarsan
7. John Vane, Sergio found that snake venom strongly blocked the enzyme ACE, thereby preventing the
Ferrereira conversion of Angiotensin I into the blood pressure raising peptide Angiotensin II
8. Dorothy Hodgkin used X-ray crystallography to crack the 4-membered ring structure of penicillin
9. Ernst Chain A fugitive from the Nazis who extracted penicillin from mould
10. Marcel Janbon head of montplier med school, studying a number of sulfanilamide analogues,
seeking a drug to treat the typhus infections
11. Klaus Fuchs rediscovered the sugar-lowering properties of sulfanilamide analogues; injected
and experienced hypoglycaemic ettects himself
12. Akiro Endo discovered lovastatin simultaneously w researches from beecham pharmaceuticals
13. Friedrich W. Ser- isolated poppy seeds and confirmed sleep-inducing ettects in dogs
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