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University of Texas, Arlington
Antimicrobial/Antibiotic/Antifungal/TB/Anti
viral Review Questions
Course: NURS 5344
1
, Antimicrobial/Antibiotic/Antifungal/TB/Antiviral Review Questions
1. The primary mechanism of antibacterial action of the penicillins involves inhibition of:
a. Beta-lactamases
b. N-acetylmuramic acid synthesis
c. cell wall synthesis by binding and inactivating penicillin binding proteins (PBPs)
d. Synthesis of cell membranes
e. Transglycosylation
2. Which statement about vancomycin is accurate?
a. Active against methicillin-resistant staphylococci
b. Bacteriostatic
c. Binds to penicillin-binding proteins (PBPs)
d. Hepatic metabolism
e. Oral bioavailability
3. The mechanism of action of the tetracyclines involves:
a. Inhibiting viral cell walls
b. Inhibiting folic acid synthesis
c. Inhibition of DNA-dependent RNA polymerase
d. Inhibiting protein synthesis
e. Inhibiting fungal cell walls
4. Regarding the mechanism of action of aminoglycosides, the drugs:
a. Are very safe with few adverse reactions
b. Are bactericidal at very low drug concentrations
c. Cause misreading of the code on the mRNA template to inhibit protein synthesis
d. Are more effective when given in multiple smaller doses
5. Which statement is accurate regarding the antibacterial action of gentamicin?
a. Antibacterial activity is often reduced by the presence of an inhibitor of cell wall
synthesis
b. Antibacterial action is not concentration-dependent
c. Antibacterial action is time dependent
d. Efficacy is directly proportional to the duration of time that the plasma level is
greater than the minimal inhibitory concentration
e. Gentamicin continues to exert antibacterial effects even after plasma levels decrease
below detectable levels
6. If a patient was treated with a macrolide erythromycin, he/she should:
a. Avoid exposure to sunlight
b. Avoid taking supplementary iron tablets
c. Have her renal function checked before treatment
d. Temporarily stop her simvastatin while taking erythromycin
2
University of Texas, Arlington
Antimicrobial/Antibiotic/Antifungal/TB/Anti
viral Review Questions
Course: NURS 5344
1
, Antimicrobial/Antibiotic/Antifungal/TB/Antiviral Review Questions
1. The primary mechanism of antibacterial action of the penicillins involves inhibition of:
a. Beta-lactamases
b. N-acetylmuramic acid synthesis
c. cell wall synthesis by binding and inactivating penicillin binding proteins (PBPs)
d. Synthesis of cell membranes
e. Transglycosylation
2. Which statement about vancomycin is accurate?
a. Active against methicillin-resistant staphylococci
b. Bacteriostatic
c. Binds to penicillin-binding proteins (PBPs)
d. Hepatic metabolism
e. Oral bioavailability
3. The mechanism of action of the tetracyclines involves:
a. Inhibiting viral cell walls
b. Inhibiting folic acid synthesis
c. Inhibition of DNA-dependent RNA polymerase
d. Inhibiting protein synthesis
e. Inhibiting fungal cell walls
4. Regarding the mechanism of action of aminoglycosides, the drugs:
a. Are very safe with few adverse reactions
b. Are bactericidal at very low drug concentrations
c. Cause misreading of the code on the mRNA template to inhibit protein synthesis
d. Are more effective when given in multiple smaller doses
5. Which statement is accurate regarding the antibacterial action of gentamicin?
a. Antibacterial activity is often reduced by the presence of an inhibitor of cell wall
synthesis
b. Antibacterial action is not concentration-dependent
c. Antibacterial action is time dependent
d. Efficacy is directly proportional to the duration of time that the plasma level is
greater than the minimal inhibitory concentration
e. Gentamicin continues to exert antibacterial effects even after plasma levels decrease
below detectable levels
6. If a patient was treated with a macrolide erythromycin, he/she should:
a. Avoid exposure to sunlight
b. Avoid taking supplementary iron tablets
c. Have her renal function checked before treatment
d. Temporarily stop her simvastatin while taking erythromycin
2
