Update)l Psychopharmacologyl forl
Advancedl Psychiatricl Mentall Healthl
Practice|l 100%l Verifiedl Questionsl &l
Answersl |l Gradel A
Q:l Al combatl veteranl presentsl withl anxiety,l flashbacks,l distressingl dreams,l irritablel
mood,l andl sleepl disturbance.l Thel patient'sl capacityl forl enjoymentl isl limitedl andl thel
patientl avoidsl peoplel andl placesl thatl triggerl memoriesl ofl combatl duel tol anxietyl andl
feelingl uncomfortable.
Whichl medicationl shouldl bel usedl tol treatl thisl patient?
a.l Olanzapinel (Zyprexa)
b.l Selegilinel (Emsam)
c.l Quetiapinel (Seroquel)
d.l Sertralinel (Zoloft)
Answer:
ANS:l Dl
Sertralinel (Zoloft)l isl thel appropriatel medicationl forl thisl patient,l whol presentsl withl
symptomsl consistentl withl post-traumaticl stressl disorderl (PTSD).l Selectivel serotoninl
reuptakel inhibitorsl (SSRIs)l suchl asl sertralinel arel first-linel pharmacologicl treatmentsl forl
PTSDl duel tol theirl efficacyl inl reducingl anxiety,l intrusivel thoughts,l andl hyperarousall
symptoms.l Atypicall antipsychoticsl likel olanzapinel andl quetiapinel mayl bel usedl asl
adjunctivel treatmentsl butl arel notl first-line.l Selegilinel isl al monoaminel oxidasel inhibitorl
(MAOI)l primarilyl usedl forl Parkinson'sl diseasel andl depression,l notl PTSD.l Thus,l
sertralinel isl thel bestl optionl forl treatingl PTSDl symptomsl inl thisl combatl veteran.
Q:l Al nursel practitionerl (NP)l completesl anl assessmentl forl thel presencel ofl abnormall
involuntaryl movementsl onl al patientl whol hasl beenl takingl variousl psychotropicl
medicationsl forl thel pastl severall years.l Thel NPl diagnosesl thel patientl withl tardivel
dyskinesial (TD).Whichl medicationl shouldl bel prescribedl tol treatl thel patient?
,a.l Duloxetinel (Cymbalta)
b.l Phenelzinel (Nardil)
c.l Propranololl (Inderal)
d.l Deutetrabenazinel (Austedo)
Answer:
ANS:l Dl
Deutetrabenazinel (Austedo)l isl thel appropriatel medicationl forl treatingl tardivel dyskinesial
(TD).l TDl isl al movementl disorderl characterizedl byl repetitive,l involuntaryl movements,l
oftenl causedl byl long-terml usel ofl dopamine-blockingl agentsl suchl asl antipsychotics.l
Deutetrabenazinel isl al vesicularl monoaminel transporterl 2l (VMAT2)l inhibitor,l whichl
helpsl reducel dopaminel releasel andl mitigatel abnormall involuntaryl movements.l Duloxetinel
isl al serotonin-norepinephrinel reuptakel inhibitorl (SNRI)l usedl forl depressionl andl chronicl
painl conditions.l Phenelzinel isl al monoaminel oxidasel inhibitorl (MAOI)l usedl forl
treatment-resistantl depression,l notl TD.l Propranololl isl al beta-blockerl usedl primarilyl forl
essentiall tremorsl andl akathisial butl isl notl effectivel forl TD.l Thus,l deutetrabenazinel isl thel
bestl choicel forl treatingl TDl inl thisl patient.
Q:l Al patientl withl al historyl ofl sociall anxietyl andl nol previousl medicationl historyl
recentlyl startedl college.l Uponl movingl intol thel dormitories,l thel patientl immediatelyl
experiencedl heightenedl anxietyl andl reportedl lowl moods.
Whichl medicationl shouldl bel usedl tol addressl thesel symptoms?
a.l Olanzapinel (Zyprexa)
b.l Risperidonel (Risperdal)
c.l Paroxetinel (Paxil)
d.l Aripiprazolel (Abilify)
Answer:
ANS:l Cl
Paroxetinel (Paxil)l isl thel appropriatel medicationl forl thisl patient,l whol presentsl withl
symptomsl consistentl withl sociall anxietyl disorderl (SAD)l andl possiblyl comorbidl
depressivel symptoms.l Selectivel serotoninl reuptakel inhibitorsl (SSRIs)l suchl asl paroxetinel
arel thel first-linel pharmacologicl treatmentl forl sociall anxietyl disorderl duel tol theirl
efficacyl inl reducingl excessivel fear,l anxiety,l andl avoidancel behaviorsl inl sociall situations.
Olanzapine,l risperidone,l andl aripiprazolel arel atypicall antipsychotics,l whichl arel notl first-
linel treatmentsl forl sociall anxietyl disorder.l Whilel theyl mayl bel usedl adjunctivelyl inl
treatment-resistantl casesl orl forl comorbidl conditionsl suchl asl schizophrenial orl bipolarl
,disorder,l theyl arel notl thel primaryl choicel forl thisl patient'sl presentation.l Thus,l paroxetinel
isl thel bestl choicel tol treatl sociall anxietyl andl lowl moodl inl thisl collegel student.
Q:l Al seven-year-oldl childl isl referredl tol thel schooll psychologistl forl ongoingl
disturbancesl inl thel classroom.l Thel childl strugglesl withl inattention,l restlessness,l
impulsivity,l andl excessivel talking.l Afterl multiplel sessionsl withl thel child,l thel schooll
psychologistl decidesl tol referl thel childl tol al locall nursel practitionerl (NP)l basedl onl al
diagnosisl ofl attentionl deficitl hyperactivityl disorderl (ADHD).
Whichl medicationl shouldl thisl NPl prescribe?
a.l Amphetaminel (Adzenysl ER)
b.l Quetiapinel (Seroquel)
c.l Olanzapinel (Zyprexa)
d.l Cariprazinel (Vraylar)
Answer:
ANS:l Al
Amphetaminel (Adzenysl ER)l isl thel appropriatel medicationl forl thisl child,l whol presentsl
withl symptomsl consistentl withl attentionl deficitl hyperactivityl disorderl (ADHD).l Stimulantl
medications,l suchl asl amphetaminesl andl methylphenidate,l arel first-linel treatmentsl forl
ADHDl andl arel highlyl effectivel inl improvingl attention,l reducingl impulsivity,l andl
managingl hyperactivity.
Quetiapine,l olanzapine,l andl cariprazinel arel atypicall antipsychotics,l whichl arel notl first-
linel treatmentsl forl ADHD.l Thesel medicationsl arel typicallyl usedl forl conditionsl suchl asl
schizophrenial orl bipolarl disorderl andl arel notl recommendedl forl managingl ADHDl
symptomsl inl children.l Thus,l amphetaminel (Adzenysl ER)l isl thel bestl choicel forl treatingl
thisl child'sl ADHDl symptoms.
Q:l Al school-agel childl diagnosedl withl separationl anxietyl disorderl andl treatedl withl
psychotherapyl continuesl tol exhibitl symptoms.l Thel childl hasl notl beenl ablel tol attendl
kindergarten.
Whichl medicationl shouldl bel usedl tol treatl thisl disorder?
a.l Citalopraml (Celexa)
b.l Clonidinel (Catapres)
c.l Aripiprazolel (Abilify)
d.l Amitriptylinel (Elavil)
, Answer:
ANS:l Al
Citalopraml (Celexa)l isl thel appropriatel medicationl forl thisl child,l whol presentsl withl
separationl anxietyl disorderl (SAD)l thatl hasl notl respondedl tol psychotherapyl alone.l
Selectivel serotoninl reuptakel inhibitorsl (SSRIs),l suchl asl citalopram,l arel thel first-linel
pharmacologicl treatmentl forl pediatricl anxietyl disorders,l includingl separationl anxiety.l
SSRIsl helpl reducel excessivel fear,l distress,l andl avoidancel behaviors,l enablingl thel childl
tol betterl copel withl beingl apartl froml caregivers.
Clonidinel isl anl alpha-2l adrenergicl agonistl primarilyl usedl forl ADHD-relatedl
hyperactivityl andl impulsivity,l notl separationl anxiety.l Aripiprazolel isl anl atypicall
antipsychoticl usedl forl conditionsl likel autism-relatedl irritability,l bipolarl disorder,l andl
schizophrenia,l notl first-linel forl anxietyl disorders.l Amitriptylinel isl al tricyclicl
antidepressantl (TCA)l thatl isl notl commonlyl usedl inl childrenl duel tol itsl sidel effectl
profilel andl riskl ofl toxicity.l Thus,l citalopraml isl thel bestl choicel forl treatingl separationl
anxietyl disorderl inl thisl child.
Q:l Al nursel practitionerl (NP)l hasl al patientl whol isl takingl lamotriginel (Lamictal)l forl
bipolarl maintenance.l Thel patientl isl welll maintainedl onl thel medication.l Thel patientl
expressesl al desirel tol startl orall contraceptives.
Whichl psychoeducationl shouldl thel NPl providel tol thel patientl inl responsel tol thisl
request?
a.l Itl isl okayl forl thel patientl tol startl thel orall contraceptivel ifl thel patientl remainsl inl
contactl withl thel NP.
b.l Somel orall contraceptivesl mayl increasel lamotriginel levels,l sol thel dosagel mayl needl tol
bel decreased.
c.l Lamotriginel isl contraindicated,l sol itl needsl tol bel cross-titratedl tol anotherl moodl
stabilizer.
d.l Somel orall contraceptivesl mayl decreasel lamotriginel levels,l sol thel dosel mayl needl tol
bel increased.
Answer:
ANS:l D
Somel orall contraceptivesl mayl decreasel lamotriginel levels,l sol thel dosel mayl needl tol bel
increased.l Estrogen-containingl orall contraceptivesl canl inducel thel metabolisml ofl
lamotriginel byl increasingl thel activityl ofl glucuronidation,l leadingl tol reducedl lamotriginel
plasmal concentrationsl andl potentiallyl decreasedl efficacyl inl moodl stabilization.l Thisl