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PATHOPHYSIOLOGY EXAM 1 PRACTICE
PROBLEMS 2026 REAL QUESTIONS WITH
EXPERTLY VERIFIED ANSWERS.
Antibodies are produced by:
A. B cells
B. T cells
C. helper cells
E. memory cells - correct answer -A
Which immunoglobulin presents the first challenge to the antigen?
A. IgA
B. IgG
C. IgM
D. IgE - correct answer -C
When the body produces antibodies against its own tissue, the
condition is called
A. alloimmunity
B. opsonization
C. autoimmunity
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D. hypersensitivity - correct answer -C
DiGeorge syndrome is a primary immune deficiency caused by:
A. failure of B cells to mature
B. congenital lack of thymic tissue
C. Failure of formed elements of blood to develop
D. Selective IgG deficiency
E. Selective IgA deficiency - correct answer -B
A nurse is explaining to a pt the difference between primary and
secondary immunodeficiency disorders and explains that
secondary immunodeficiencies (select all that apply):
A. May develop after viral infections
B. Develop before birth
C. May develop following immunosuppressive therapies
D. Are caused by superimposed conditions
E. Are not always readily evident - correct answer -A, C, D, E
A pt presents with a rash from poison ivy. The nurse knows that
this is which type of hypersensitivity?
A. Type I
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B. Type II
C. Type III
D. Type IV - correct answer -D
Which is not an autoimmune disease?
A. multiple sclerosis
B. pernicious anemia
C. ulcerative colitis
D. transfusion reaction
E. goodpasture disease - correct answer -D
A nurse is teaching a class about immune deficiencies, and a
person from the audience asks which cells are affected by severe
combined immune deficiency (SCID) syndrome, and the nurse
answers:
A. B cell deficits
B. T cell deficits
C. complement deficits
D. B and T cell deficits - correct answer -D
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When a patient asks the nurse what hypersensitivity is, how
should the nurse respond? Hypersensitivity is best defined as:
A. a reduced immune response found in most pathologic states
B. a normal immune response to an infectious agent
C. an excessive or inappropriate response of immune system to
sensitizing antigen
D. antigenic desensitization - correct answer -C
When the maternal immune system becomes sensitized against
antigens expressed by the fetus, what type of immune reaction
occurs?
A. autoimmune
B. anaphylaxis
C. alloimmune
D. allergic - correct answer -C
Which information would indicate more teaching is needed
regarding hypersensitivity reactions? Type _______
hypersensitivity reactions involve an antibody response.
A. I
B. II
C. III
D. IV - correct answer -D
PATHOPHYSIOLOGY EXAM 1 PRACTICE
PROBLEMS 2026 REAL QUESTIONS WITH
EXPERTLY VERIFIED ANSWERS.
Antibodies are produced by:
A. B cells
B. T cells
C. helper cells
E. memory cells - correct answer -A
Which immunoglobulin presents the first challenge to the antigen?
A. IgA
B. IgG
C. IgM
D. IgE - correct answer -C
When the body produces antibodies against its own tissue, the
condition is called
A. alloimmunity
B. opsonization
C. autoimmunity
, Page | 2
D. hypersensitivity - correct answer -C
DiGeorge syndrome is a primary immune deficiency caused by:
A. failure of B cells to mature
B. congenital lack of thymic tissue
C. Failure of formed elements of blood to develop
D. Selective IgG deficiency
E. Selective IgA deficiency - correct answer -B
A nurse is explaining to a pt the difference between primary and
secondary immunodeficiency disorders and explains that
secondary immunodeficiencies (select all that apply):
A. May develop after viral infections
B. Develop before birth
C. May develop following immunosuppressive therapies
D. Are caused by superimposed conditions
E. Are not always readily evident - correct answer -A, C, D, E
A pt presents with a rash from poison ivy. The nurse knows that
this is which type of hypersensitivity?
A. Type I
, Page | 3
B. Type II
C. Type III
D. Type IV - correct answer -D
Which is not an autoimmune disease?
A. multiple sclerosis
B. pernicious anemia
C. ulcerative colitis
D. transfusion reaction
E. goodpasture disease - correct answer -D
A nurse is teaching a class about immune deficiencies, and a
person from the audience asks which cells are affected by severe
combined immune deficiency (SCID) syndrome, and the nurse
answers:
A. B cell deficits
B. T cell deficits
C. complement deficits
D. B and T cell deficits - correct answer -D
, Page | 4
When a patient asks the nurse what hypersensitivity is, how
should the nurse respond? Hypersensitivity is best defined as:
A. a reduced immune response found in most pathologic states
B. a normal immune response to an infectious agent
C. an excessive or inappropriate response of immune system to
sensitizing antigen
D. antigenic desensitization - correct answer -C
When the maternal immune system becomes sensitized against
antigens expressed by the fetus, what type of immune reaction
occurs?
A. autoimmune
B. anaphylaxis
C. alloimmune
D. allergic - correct answer -C
Which information would indicate more teaching is needed
regarding hypersensitivity reactions? Type _______
hypersensitivity reactions involve an antibody response.
A. I
B. II
C. III
D. IV - correct answer -D
