1|Page
Comprehensive HESI Med-Surg II Exam Test Bank
2026-2027 Edition | 150+ Verified Questions and
answers | Detailed Rationales | A+ Grade Guaranteed
Domain Content Area Q&A Count
I Cardiovascular Disorders 30
II Respiratory Disorders 25
III Neurological Disorders 25
IV Gastrointestinal Disorders 25
V Renal & Urinary Disorders 20
VI Endocrine Disorders 20
VII Hematological & Immunological Disorders 20
VIII Musculoskeletal Disorders 20
IX Integumentary Disorders 15
X Oncological Disorders 15
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Domain Content Area Q&A Count
XI Infectious Diseases 10
XII NGN Case Studies 10
PART I: Cardiovascular Disorders
1. A nurse is caring for a patient with heart failure who has gained 4
lbs in 24 hours. Which of the following is the priority nursing
action?
A) Document the weight gain
B) Assess lung sounds and respiratory status
C) Restrict fluids to 500 mL/day
D) Notify the healthcare provider
Answer: B) Assess lung sounds and respiratory status
Rationale: Weight gain of 2-3 lbs in 24 hours indicates fluid overload.
The priority is to assess for signs of pulmonary congestion (crackles,
dyspnea) before intervening. Notifying the provider (D) and fluid
restriction (C) may be needed after assessment.
2. A patient with heart failure is prescribed furosemide (Lasix).
Which of the following laboratory values should the nurse monitor
closely?
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A) Serum sodium
B) Serum potassium
C) Serum calcium
D) Serum magnesium
Answer: B) Serum potassium
Rationale: Furosemide is a loop diuretic that causes potassium wasting.
Hypokalemia can lead to cardiac arrhythmias, especially in patients
taking digoxin. Serum potassium should be monitored regularly.
3. A nurse is assessing a patient with left-sided heart failure. Which
of the following findings is characteristic?
A) Jugular venous distension
B) Peripheral edema
C) Crackles in the lung bases
D) Hepatomegaly
Answer: C) Crackles in the lung bases
Rationale: Left-sided heart failure causes pulmonary congestion
(crackles, dyspnea, orthopnea). Right-sided heart failure (A, B, D)
causes peripheral edema, JVD, and hepatomegaly.
4. A patient with heart failure is prescribed digoxin. Which of the
following findings indicates digoxin toxicity?
A) Heart rate 72 bpm
B) Nausea and vomiting
C) Blood pressure 130/80
D) Weight loss
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Answer: B) Nausea and vomiting
Rationale: Early signs of digoxin toxicity include nausea, vomiting,
anorexia, and visual disturbances (yellow halos). Bradycardia (hold if
HR <60) is also a sign. The nurse should assess apical pulse before
administration.
5. A patient is admitted with acute myocardial infarction (MI).
Which of the following laboratory values is most specific for
myocardial damage?
A) Creatine kinase-MB (CK-MB)
B) Troponin I
C) Myoglobin
D) C-reactive protein
Answer: B) Troponin I
Rationale: Troponin I is the most specific and sensitive marker for
myocardial damage. It rises within 3-4 hours, peaks at 12-24 hours, and
remains elevated for 7-10 days. CK-MB (A) is less specific. Myoglobin
(C) rises early but is not specific.
6. A patient with an acute MI has a heart rate of 120 bpm and blood
pressure of 85/50 mm Hg. Which of the following is the priority
action?
A) Administer morphine
B) Administer nitroglycerin
C) Administer dobutamine
D) Notify the provider immediately
Comprehensive HESI Med-Surg II Exam Test Bank
2026-2027 Edition | 150+ Verified Questions and
answers | Detailed Rationales | A+ Grade Guaranteed
Domain Content Area Q&A Count
I Cardiovascular Disorders 30
II Respiratory Disorders 25
III Neurological Disorders 25
IV Gastrointestinal Disorders 25
V Renal & Urinary Disorders 20
VI Endocrine Disorders 20
VII Hematological & Immunological Disorders 20
VIII Musculoskeletal Disorders 20
IX Integumentary Disorders 15
X Oncological Disorders 15
,2|Page
Domain Content Area Q&A Count
XI Infectious Diseases 10
XII NGN Case Studies 10
PART I: Cardiovascular Disorders
1. A nurse is caring for a patient with heart failure who has gained 4
lbs in 24 hours. Which of the following is the priority nursing
action?
A) Document the weight gain
B) Assess lung sounds and respiratory status
C) Restrict fluids to 500 mL/day
D) Notify the healthcare provider
Answer: B) Assess lung sounds and respiratory status
Rationale: Weight gain of 2-3 lbs in 24 hours indicates fluid overload.
The priority is to assess for signs of pulmonary congestion (crackles,
dyspnea) before intervening. Notifying the provider (D) and fluid
restriction (C) may be needed after assessment.
2. A patient with heart failure is prescribed furosemide (Lasix).
Which of the following laboratory values should the nurse monitor
closely?
,3|Page
A) Serum sodium
B) Serum potassium
C) Serum calcium
D) Serum magnesium
Answer: B) Serum potassium
Rationale: Furosemide is a loop diuretic that causes potassium wasting.
Hypokalemia can lead to cardiac arrhythmias, especially in patients
taking digoxin. Serum potassium should be monitored regularly.
3. A nurse is assessing a patient with left-sided heart failure. Which
of the following findings is characteristic?
A) Jugular venous distension
B) Peripheral edema
C) Crackles in the lung bases
D) Hepatomegaly
Answer: C) Crackles in the lung bases
Rationale: Left-sided heart failure causes pulmonary congestion
(crackles, dyspnea, orthopnea). Right-sided heart failure (A, B, D)
causes peripheral edema, JVD, and hepatomegaly.
4. A patient with heart failure is prescribed digoxin. Which of the
following findings indicates digoxin toxicity?
A) Heart rate 72 bpm
B) Nausea and vomiting
C) Blood pressure 130/80
D) Weight loss
, 4|Page
Answer: B) Nausea and vomiting
Rationale: Early signs of digoxin toxicity include nausea, vomiting,
anorexia, and visual disturbances (yellow halos). Bradycardia (hold if
HR <60) is also a sign. The nurse should assess apical pulse before
administration.
5. A patient is admitted with acute myocardial infarction (MI).
Which of the following laboratory values is most specific for
myocardial damage?
A) Creatine kinase-MB (CK-MB)
B) Troponin I
C) Myoglobin
D) C-reactive protein
Answer: B) Troponin I
Rationale: Troponin I is the most specific and sensitive marker for
myocardial damage. It rises within 3-4 hours, peaks at 12-24 hours, and
remains elevated for 7-10 days. CK-MB (A) is less specific. Myoglobin
(C) rises early but is not specific.
6. A patient with an acute MI has a heart rate of 120 bpm and blood
pressure of 85/50 mm Hg. Which of the following is the priority
action?
A) Administer morphine
B) Administer nitroglycerin
C) Administer dobutamine
D) Notify the provider immediately
