AMT MLT MEDICAL LABORATORY
TECHNICIANS CERTIFICATION
STUDY GUIDE 2026
COMPREHENSIVE QUESTIONS AND
VERIFIED ANSWERS WITH
RATIONALES
◉ What inhibits vitamin K dependent coagulation factors? Answer:
Warfarin (oral)
◉ Factor VIII deficiency is also called Answer: Hemophilia A
◉ Factor IX deficiency is also called Answer: Hemophilia B
◉ What evaluates adequacy of fibrinogen in heparinized pts? Answer:
RPR
◉ von Willebrand factor Answer: Mediate a bridge between
glycoprotein complex on platelets and collagen on sub endothelial
surface (defect can cause impaired platelet adhesion and aggregation)
◉ Stuart-Prower factor Answer: X-factor, is a part of cleaning
prothrombin into thrombin
,◉ Hageman factor Answer: Factor XII, is in the intrinsic pathway,
activates Fletcher factor
◉ Fletcher Factor Answer: Pre-K in intrinsic pathway and activates
factor XI
◉ Streptokinase Answer: Exogenous activator for plasminogen in
fibrinolytic system
◉ What is the end product of coagulation cascade? Answer: fibrin
◉ Intrinsic and common passway Answer: aPTT
◉ extrinsic and common pathways Answer: PT
◉ Average bleeding time Answer: 1-7min
◉ Common pathway factors Answer: X, V, II, I
◉ extrinsic factors Answer: VII
◉ intrinsic factors Answer: XII, XI, IX, VIII
,◉ Fibrinolysis Answer: dissolution of a clot
◉ Primary homeostasis Answer: Formation of non-stable platelet plug
◉ Secondary homeostasis Answer: Formation of durable fibrin strand
◉ Most specific fibrinogen function test, not affected by heparin
Answer: thrombin time
◉ Non-specific fibrinogen function test Answer: PT and PTT
◉ VLDL Answer: endogenous triglycerides transport
◉ Chylomicrons Answer: exogenous triglycerides transport
◉ HDL and LDL Answer: Cholesterol transport
◉ adult hemoglobin Answer: 2 alpha and 2 beta chains
◉ fetal hemoglobin Answer: 2 alpha and 2 gamma
◉ Hemoglobin A2 Answer: 2 alpha and 2 delta
, ◉ Type I hypersensitivity Answer: IgE mediated
◉ Type II hypersensitivity Answer: IgG
◉ Type III hypersensitivity Answer: IgM and IgG
◉ Heinz bodies lead to Answer: G6PD deficiency
◉ Microangiopathic Hemolytic Anemia Answer: Schistocytes
ceratocytes and teardrop cells
◉ Abetalipoproteinemia Answer: Acanthocytes
◉ Beta Thalassemia Answer: target cells (codocytes)
◉ Howell-Jolly bodies Answer: DNA
◉ Heinz bodies Answer: denatured hemoglobin
◉ Papperheimer bodies Answer: Nonferritin iron
TECHNICIANS CERTIFICATION
STUDY GUIDE 2026
COMPREHENSIVE QUESTIONS AND
VERIFIED ANSWERS WITH
RATIONALES
◉ What inhibits vitamin K dependent coagulation factors? Answer:
Warfarin (oral)
◉ Factor VIII deficiency is also called Answer: Hemophilia A
◉ Factor IX deficiency is also called Answer: Hemophilia B
◉ What evaluates adequacy of fibrinogen in heparinized pts? Answer:
RPR
◉ von Willebrand factor Answer: Mediate a bridge between
glycoprotein complex on platelets and collagen on sub endothelial
surface (defect can cause impaired platelet adhesion and aggregation)
◉ Stuart-Prower factor Answer: X-factor, is a part of cleaning
prothrombin into thrombin
,◉ Hageman factor Answer: Factor XII, is in the intrinsic pathway,
activates Fletcher factor
◉ Fletcher Factor Answer: Pre-K in intrinsic pathway and activates
factor XI
◉ Streptokinase Answer: Exogenous activator for plasminogen in
fibrinolytic system
◉ What is the end product of coagulation cascade? Answer: fibrin
◉ Intrinsic and common passway Answer: aPTT
◉ extrinsic and common pathways Answer: PT
◉ Average bleeding time Answer: 1-7min
◉ Common pathway factors Answer: X, V, II, I
◉ extrinsic factors Answer: VII
◉ intrinsic factors Answer: XII, XI, IX, VIII
,◉ Fibrinolysis Answer: dissolution of a clot
◉ Primary homeostasis Answer: Formation of non-stable platelet plug
◉ Secondary homeostasis Answer: Formation of durable fibrin strand
◉ Most specific fibrinogen function test, not affected by heparin
Answer: thrombin time
◉ Non-specific fibrinogen function test Answer: PT and PTT
◉ VLDL Answer: endogenous triglycerides transport
◉ Chylomicrons Answer: exogenous triglycerides transport
◉ HDL and LDL Answer: Cholesterol transport
◉ adult hemoglobin Answer: 2 alpha and 2 beta chains
◉ fetal hemoglobin Answer: 2 alpha and 2 gamma
◉ Hemoglobin A2 Answer: 2 alpha and 2 delta
, ◉ Type I hypersensitivity Answer: IgE mediated
◉ Type II hypersensitivity Answer: IgG
◉ Type III hypersensitivity Answer: IgM and IgG
◉ Heinz bodies lead to Answer: G6PD deficiency
◉ Microangiopathic Hemolytic Anemia Answer: Schistocytes
ceratocytes and teardrop cells
◉ Abetalipoproteinemia Answer: Acanthocytes
◉ Beta Thalassemia Answer: target cells (codocytes)
◉ Howell-Jolly bodies Answer: DNA
◉ Heinz bodies Answer: denatured hemoglobin
◉ Papperheimer bodies Answer: Nonferritin iron
