MN 580 MIDTERM COMPREHENSIVE STUDY
GUIDE 2026 FULL QUESTIONS AND
SOLUTIONS GRADED A+
• SVC syndrome diagnostics.
Answer: -chest xray and CT chest with contrast to determine if obstruction
can be relieved with chemo/radiation (tumor) or with tpa (thrombosis)
• ways of establishing trust with a child/adolescent.
Answer: give them candy
• T/F: Affordability requirement applies to individual coverage only.
Answer: True
• diagnostic value of joint pattern.
Answer: osteoarthritis: inflammation absent, monoarticular, present in distal
interphalangeals, first metatarsal, or phalangeals rheumatic arthritis:
inflammation present, polyarticular, present in metacarpo-phalangeals or
wrists gout: inflammation present, monoarticular, present in first metatarsal
or phalangeals
• T/F: Pharmacogenomics attempts to predict how different patients will
respond to medications based on their genetic variations.
Answer: True
• Human Genome Project (2003).
Answer: Project that sequenced the human genome to support biomedical
research. $2.7 billion, over 100 individual samples
• psychotic symptoms of dorsolateral prefrontal cortex.
Answer: cognitive symptoms
• system that incorporates amygdala, hippocampus, nucleus accumbens and
thalamus.
Answer: limbic system
,• 5HT6 action.
Answer: post-synaptic regulate ACh which controls cognitive processes
blocking 5HT6= increased learning and memory
• hypercalcemia s/s.
Answer: -neuro: AMS or obtunded -muscular: weakness to absent DT
reflexes -cardiac: bradycardia, heart block, vtach, asystole -GI: n/v/c
• Health Insurance Coverage (Pre-ACA).
Answer: 56% employer-sponsored coverage 21% medicaid/public programs
6% private non-group 18% uninsured
• cortico-striatal glutamate pathway.
Answer: cortical pyramidal neurons--> striatal complex -terminates on
GABA neurons
• priority of the PMHNP for a patient who attempted suicide by cutting
wrists>.
Answer: obtain the vital signs
• criterion-related validity.
Answer: indicates the degree to which the performance on the measurement
tool and the actual behavior are correlated concurrent: degree of correlation
between 2 instruments predictive: strength of correlation between an
instrument and a future instrument
• Fly Vectors.
Answer: mechanical vectors must be: - be present during transmission -
contact infectious material - pick up pathogens - transfer sufficient
pathogens to another host
• importance of PROs.
Answer: provide critical data on an individual's treatment and disease
focused on assessing symptoms: physical, psychosocial, frequency, severity
impact on daily life patient satisfaction
• Distant Metastasis (M) Classification.
, Answer: MX = cannot be evaluated (trauma/surgery) M0 = no evidence of
distant metastasis M1 = distant metastasis / cancer has spread to other body
parts
• sampling.
Answer: sample: smaller collection of units from a population--used to
determine truths about a population--hopefully representative population of
interest: take a sample, and make inferences back onto the population
• upper and lower motor neuron destruction s/s.
Answer: muscle weakness, difficulty with speech and swallowing,
unsteadiness
• probability sampling.
Answer: simple random sample stratified random sampling systematic
sampling cluster sampling
• scleroderma treatment.
Answer: -symptomatic: steroids -immunosuppressants: methotrexate,
interleukin-1 inhibitors -treatment to specific organ involved
• appraising the evidence for questionnaire methods.
Answer: is the measure described adequately? is there evidence that study
participants were able to answer the questions? are the items appropriately
close- vs. open-ended?
• Team vs Individual Creativity.
Answer: - creative individuals ≠ creative team - creative leader ≠ creative
team - implement processes that support creativity - important to establish
that creativity is not easy to achieve - diversity of perspective is key
• what happens if you have low recruitment?.
Answer: evaluate your sample size and speak with statitician about what
effect this will have add new sites replace sites extend recruitment modify
inclusion criteria (maybe they are too strict)
• RVF Animal Vaccine.
GUIDE 2026 FULL QUESTIONS AND
SOLUTIONS GRADED A+
• SVC syndrome diagnostics.
Answer: -chest xray and CT chest with contrast to determine if obstruction
can be relieved with chemo/radiation (tumor) or with tpa (thrombosis)
• ways of establishing trust with a child/adolescent.
Answer: give them candy
• T/F: Affordability requirement applies to individual coverage only.
Answer: True
• diagnostic value of joint pattern.
Answer: osteoarthritis: inflammation absent, monoarticular, present in distal
interphalangeals, first metatarsal, or phalangeals rheumatic arthritis:
inflammation present, polyarticular, present in metacarpo-phalangeals or
wrists gout: inflammation present, monoarticular, present in first metatarsal
or phalangeals
• T/F: Pharmacogenomics attempts to predict how different patients will
respond to medications based on their genetic variations.
Answer: True
• Human Genome Project (2003).
Answer: Project that sequenced the human genome to support biomedical
research. $2.7 billion, over 100 individual samples
• psychotic symptoms of dorsolateral prefrontal cortex.
Answer: cognitive symptoms
• system that incorporates amygdala, hippocampus, nucleus accumbens and
thalamus.
Answer: limbic system
,• 5HT6 action.
Answer: post-synaptic regulate ACh which controls cognitive processes
blocking 5HT6= increased learning and memory
• hypercalcemia s/s.
Answer: -neuro: AMS or obtunded -muscular: weakness to absent DT
reflexes -cardiac: bradycardia, heart block, vtach, asystole -GI: n/v/c
• Health Insurance Coverage (Pre-ACA).
Answer: 56% employer-sponsored coverage 21% medicaid/public programs
6% private non-group 18% uninsured
• cortico-striatal glutamate pathway.
Answer: cortical pyramidal neurons--> striatal complex -terminates on
GABA neurons
• priority of the PMHNP for a patient who attempted suicide by cutting
wrists>.
Answer: obtain the vital signs
• criterion-related validity.
Answer: indicates the degree to which the performance on the measurement
tool and the actual behavior are correlated concurrent: degree of correlation
between 2 instruments predictive: strength of correlation between an
instrument and a future instrument
• Fly Vectors.
Answer: mechanical vectors must be: - be present during transmission -
contact infectious material - pick up pathogens - transfer sufficient
pathogens to another host
• importance of PROs.
Answer: provide critical data on an individual's treatment and disease
focused on assessing symptoms: physical, psychosocial, frequency, severity
impact on daily life patient satisfaction
• Distant Metastasis (M) Classification.
, Answer: MX = cannot be evaluated (trauma/surgery) M0 = no evidence of
distant metastasis M1 = distant metastasis / cancer has spread to other body
parts
• sampling.
Answer: sample: smaller collection of units from a population--used to
determine truths about a population--hopefully representative population of
interest: take a sample, and make inferences back onto the population
• upper and lower motor neuron destruction s/s.
Answer: muscle weakness, difficulty with speech and swallowing,
unsteadiness
• probability sampling.
Answer: simple random sample stratified random sampling systematic
sampling cluster sampling
• scleroderma treatment.
Answer: -symptomatic: steroids -immunosuppressants: methotrexate,
interleukin-1 inhibitors -treatment to specific organ involved
• appraising the evidence for questionnaire methods.
Answer: is the measure described adequately? is there evidence that study
participants were able to answer the questions? are the items appropriately
close- vs. open-ended?
• Team vs Individual Creativity.
Answer: - creative individuals ≠ creative team - creative leader ≠ creative
team - implement processes that support creativity - important to establish
that creativity is not easy to achieve - diversity of perspective is key
• what happens if you have low recruitment?.
Answer: evaluate your sample size and speak with statitician about what
effect this will have add new sites replace sites extend recruitment modify
inclusion criteria (maybe they are too strict)
• RVF Animal Vaccine.
