Pharmacology Antimicrobials Worksheet- Questions and Answers
1. Antimicrobial Chemical substances killing or inhibiting microorganisms
drugs
2. Natural antibi- Produced by microorganisms like fungi and bacteria
otics
3. Semi-synthetic Isolated from natural sources, chemically modified
drugs
4. Synthetic drugs Artificial compounds synthesized in a laboratory
5. Broad-spectrum Ettective against both gram-positive and gram-negative bacteria
drugs
6. Narrow-spectrum Ettective against a limited group of microbes
drugs
7. Nitroimidazoles Antibacterial and antiprotozoal activity
8. Metronidazole Treats giardia, amoebiasis, and anaerobic bacteria; avoid in pregnant animals
9. Rifampin Disrupts RNA synthesis, broad spectrum; used with erythromycin for Corynebac-
terium equi infections
10. Polyene Antifun- Nystatin and Amphotericin B bind to fungal cell membrane; Amphotericin B is
gal Agents extremely nephrotoxic
11. Imidazole Anti- Ketoconazole and miconazole cause leakage of fungal cell membrane; used for
fungal Agents various fungal infections
12. Flucytosine Interferes with RNA and protein metabolism; used in combination to treat Cryp-
tococcus
13. Griseofulvin Treats dermatophyte fungal infections; causes anorexia in cats and is teratogenic
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1. Antimicrobial Chemical substances killing or inhibiting microorganisms
drugs
2. Natural antibi- Produced by microorganisms like fungi and bacteria
otics
3. Semi-synthetic Isolated from natural sources, chemically modified
drugs
4. Synthetic drugs Artificial compounds synthesized in a laboratory
5. Broad-spectrum Ettective against both gram-positive and gram-negative bacteria
drugs
6. Narrow-spectrum Ettective against a limited group of microbes
drugs
7. Nitroimidazoles Antibacterial and antiprotozoal activity
8. Metronidazole Treats giardia, amoebiasis, and anaerobic bacteria; avoid in pregnant animals
9. Rifampin Disrupts RNA synthesis, broad spectrum; used with erythromycin for Corynebac-
terium equi infections
10. Polyene Antifun- Nystatin and Amphotericin B bind to fungal cell membrane; Amphotericin B is
gal Agents extremely nephrotoxic
11. Imidazole Anti- Ketoconazole and miconazole cause leakage of fungal cell membrane; used for
fungal Agents various fungal infections
12. Flucytosine Interferes with RNA and protein metabolism; used in combination to treat Cryp-
tococcus
13. Griseofulvin Treats dermatophyte fungal infections; causes anorexia in cats and is teratogenic
1/3
