Terms in this set (26)
-a solution to many cohort study limitations
- a study which cases of dz are identified, and then a sample of the population that
produced the cases is identified (controls)
-exposures are determined and compared for individuals in each group
desirable to conduct:
1. when exposure data are expensive or difficult to obtain (i.e. nested pesticide in
case control study NHS)
2. When dz has long latent period (results may take decades to emerge; i.e. cancer,
CVD)
3. when dz is rare
4. when population is difficult to follow; high loss of follow up might bias results
5. when little is known about the dz; can evaluate many exposures (i.e. early studies
of AIDS)
consider hypothesis and person, place and time when defining
1. participants in an established cohort such as NHS
source population of case control studies 2. pregnant women delivering at BMC, 2014-2015
3. People eating at restaurant x from 9/1-9/30 2016.
4. Cape Cod, MA residents during 1980s
case definition must have this to lead to accurate classification of disease
can be identified from variety of places; efficient and accurate sources should be
used
1. presenting to hospital or clinic
cases 2. population registries (state cancer registries, notifiable infectious disease
registries)
-are the same as those that would be included in a cohort study
-are "statistically precious" - enroll as many as possible