NSG 552 PSYCHO-PHARMACOLOGY WILKES STUDY GUIDE EXAM WITH ANSWERS

NSG 552 PSYCHO-PHARMACOLOGY
WILKES STUDY GUIDE EXAM WITH
ANSWERS


Bupropions role in alcohol use disorder -
answer-Can diminish cravings for etoh,
treat underlying anxiety/depression


Safety Risk associated with bupropion and
etoh - answer-bupropion increases the risk
of seizures in those going through etoh
withdrawal


First Line Treatments for alcohol use
disorder (according to Study Guide &
Dynamed) - answer-naltrexone and
acamprosate

,Second Line Treatments for alcohol use
disorder (according to study guide but not
dynamed) - answer-Disulfuram and
Bupropion (not FDA approved for ETOH
but second line according to study guide)


Second Line Treatment for alcohol use
disorder (according to Dynamed) - answer-
Disulfuram


Other off label medications for alcohol use
disorder according to Dynamed - answer-
Topiramate, gabapentin, baclofen


Other off label medications for alcohol use
disorder according to Stahl's - answer-
Topiramate, ondansetron

, MOA of Naltrexone - answer-Opioid
Receptor Antagonist


MOA of Acamprosate - answer-- weak
GABAa agonist
- weak NMDA antagonist


(does not prevent withdrawal symptoms)


MOA of Disulfuram - answer-inhibits
enzyme (aldehyde dehydrogenase) in the
liver


s/s ETOH intoxication - answer-impaired
fine motor control, impaired judgement
and coordination, ataxic gait, poor balance,
lethargy, difficulty sitting upright, difficulty