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RN HESI Exit Exam V6 2026 – 110 Questions on Med-Surg, Pediatrics, Pharmacology & Critical Care Exam

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This document contains approximately 110 multiple-choice exam questions with correct answers based on comprehensive nursing concepts aligned with HESI Comprehensive Review for the NCLEX-RN Examination and Saunders Comprehensive Review for the NCLEX-RN. It provides in-depth coverage of major nursing domains including medical-surgical nursing, pharmacology, pediatrics, maternal health, mental health, and critical care. The material is presented in a structured Q&A format designed to simulate real HESI Exit exam scenarios and enhance clinical reasoning skills. As shown in the document (pages 1–10), early questions focus on emergency care priorities, pediatric interventions, pharmacological treatments (e.g., hydrocortisone for adrenal insufficiency), and infection management. Mid-sections (pages 10–40) cover diverse clinical scenarios including cardiovascular disorders, respiratory conditions, endocrine emergencies, postoperative care, and prioritization frameworks such as ABCs and safety-first interventions. Later sections (pages 40–70+) emphasize advanced nursing decision-making, delegation, ethical considerations, medication calculations, and high-risk patient management (e.g., ventricular fibrillation requiring immediate defibrillation, electrolyte imbalances, and dialysis monitoring), ensuring strong alignment with real HESI Exit exam expectations. This resource is ideal for nursing students preparing for the RN HESI Exit Exam, NCLEX-RN, and final nursing school assessments. It is suitable for courses such as Medical-Surgical Nursing, Pharmacology, Pediatrics, Maternal-Newborn Nursing, Critical Care, and Nursing Leadership. Additionally, it benefits nursing students in ADN and BSN programs, as well as graduates preparing for licensure exams and clinical competency evaluations. Keywords: RN HESI exit exam questions, HESI V6 exam prep, NCLEX RN practice questions, medical surgical nursing scenarios, pharmacology nursing questions, pediatric nursing care, maternal newborn nursing exam, critical care nursing priorities, nursing delegation questions, prioritization ABC nursing, ventricular fibrillation defibrillation, electrolyte imbalance nursing, dosage calculations nursing, clinical decision making nursing, nursing exam preparation

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RN HESI EXIT/HESI Exit RN
Exam Version 6(V6)
Real/Actual/Authentic Exam
2026 Expert Verified | Ace the
Test



1. A mother runs into the emergency department with a toddler in her arms

and

tells the nurse that her child got into some cleaning products. the child

smells

,of chemicals on the hands, face, and on the front of the child's clothes.

after

ensuring the airway is patent, what action should the nurse implement first?

a. Assess the child for altered sensorium

b. Determine type of chemical exposure

c. Obtain equipment for gastric lavage


d. Call poison control emergency number - 🧠ANSWER ✔✔b. Determine

type of chemical exposure

2. Which conditions are most likely to respond to treatment with

antihistamines? Select all that apply.

a. Bronchitis

b. Allergic rhinitis

c. Otitis media

d. Contact dermatitis


e. Myocarditis - 🧠ANSWER ✔✔b. Allergic rhinitis


d. Contact dermatitis

,3. An older client's daughter calls the home health nurse and reports that

her

mother has become forgetful and is very confused at night. The daughter

states that her mother's behavior changed suddenly a few days ago and is

now getting worse. Which action should the nurse take? Select all that

apply.

a. Ask if the mother is experiencing any pain with urination

b. Encourage increased intake of high protein foods

c. Instruct the daughter to check her mother's temperature

d. Review the client's current food and medication allergies

e. Determine if the mother has recently experienced a fall - 🧠ANSWER

✔✔a. Ask if the mother is experiencing any pain with urination


c. Instruct the daughter to check her mother's temperature

e. Determine if the mother has recently experienced a fall

4. The nurse is assessing a male with a history of Addison's disease. The

client

has flu-like symptoms and nausea with vomiting over the past week. The


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, client's spouse reports that he acted confused and was extremely weak

when

he awoke this morning. The client is febrile and has tachycardia. The health

care provider diagnoses acute adrenal insufficiency. Which medication will

most likely be prescribed?

a. Hypertonic saline solution at 100 ml/hr until all edema disappears

b. Hydrocortisone 100 mg IV every six hours until systolic BP reaches 110

mmHg

c. Potassium chloride 20 mEq IV to infuse over 2 hours until confusion

resolves

d. Regular insulin drip to keep blood glucose around 100 mg/dl (5.55


mmol/L) - 🧠ANSWER ✔✔b. Hydrocortisone 100 mg IV every six hours until

systolic BP reaches 110

mmHg

5. A client with a history of mitral valve prolapse is admitted because of

fever

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