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HITM(heparinMinducedMthrombocytopenia)M-
MAnswerMBivalirudinMandMArgatrobanMareMdirectMthrombinMinhibitorsMandMalternativesMf
orManticoagulationMforMpatientsMwithMHIT.
-
MHITMisManMimmuneMmediatedMadverseMdrugMreactionMcausedMbyMantibodiesMthatMdev
elopMafterMexposureMtoMheparin,MplateletsMbecomeMactivatedMplacingMpatientsMatMriskM
forMdevelopmentMofMthrombosis
pericarditisM-MAnswerMinflammationMofMpericardialMsac,MchestMpain-
sharp,stabbing,Mdull,MachyM
painMimprovedMwithMsittingM&leaningMfoward,MpainMworseMwithMcough,MpositionalMchan
gesMandMinspiration,
pericardialMfrictionMrub,Mfever,MDiffuseMSTMchangesM(depressionMofMPRMinterval,Mconcav
eMSTMsegmentMinMlimbMleads,stMelevationMinMleadsMIMandMII
PapillaryMmuscleMruptureM-MAnswerM-associatedMwithManteriorMorMinferiorMwallMMI
-
MhemodynamicMinstability,MnewMloudMsystolicMmurmur,MacuteMmitralMregurgitation,Mlarge
MVMwavesMonMPAOPMwaveform
-MtreatmentM-MhemodynamicMsupport,MEmergentMsurgicalMrepair/valveMreplacement
VentricularMseptalMruptureM-MAnswerM-associatedMwithMseptalMwallMMI
-oxygenMrichMbloodMshuntsMtoMrightMsideMofMheartMfromMtheMleft
SymptomsMofMventricularMseptalMruptureM-MAnswerM-acuteMSOB
-S3MheartMsound
-crackles
-holosystolicMmurmur
-MPAMCatheterMinsertion--
>MfalselyMincreaedMCO,MbecauseMCOMreadingMisMderivedMfromMtheMrightMventricle,Minc
reasedMSvo2MdueMtoMleftMtoMrightMshunting,MlargeMVMwavesMonMCVPMwaveform,Mdiag
nosedMbyMECHO
-MtreatementMsurgicalMrepair
,cardiogenicMshockM-
MAnswerMS3MpulmonaryMedema,Mtachycardia,Mdysrhythmias,MsignsMofMdecreasedMperfusi
onM(mottling),MdecreasedMUOPM<0.5ml/kg/hr,Mhypotension,MlowMCO/CI,MelevatedMSVRMof
tenM>M1600Mdynes/sec/cm,MelevatedMRAP/CVP,MPAOPM>16Mmmhg,MdecreasedMsvo2M(<6
5%)
otherMdiagnosticsMforMcardiogenicMshockM-MAnswerM-
McardiacMcatheterizationMifMrelatedMtoMischemia-MPCIMforMreperfusion
-MABG-MmixedMrespiratoryMandMmetabolicMacidosis:hypoxemia-
MlacticMacidosisMdueMtoMdecreasedMperfusionMandManaerobicMmetabolism
-ECHO:MdecreasedMwallMmotion,reducedMejectionMfraction
-
Chestxray:MpulmonaryMedemaM&congestion,MmayMnoteMopacityMdueMtoMenlargedMpulmo
naryMvasculature,MenlargeMdMheart,MKerleyMBMlinesMinMlowerMzonesMfromMinterstitialMe
dema,M
-MBUN/CR-MmonitorMforMacuteMkidneyMinjury
-MmonitorMotherMorgansMforMdysfunctionMandMfailure
supportiveMtreatmentMforMcardiogenicMshockM-MAnswerM-
mechanicalMsupportM(IABP,impella)
-
vasopressorsMtoMsupportMbloodMpressureM(useMwithMcautionMasMtheyMincreaseMSVRMan
dMworkloadMofMheart)
-positiveMinotropeMtoMimproveMcontractilityM
-diureticsM
afterloadMreductionM/MvenousMvasodilators
cardiogenicMpulmonaryMedemaM-MAnswerM-
fluidMinMtheMalveolusMdueMtoMincreasedMalveolarMhydrostaticMpressures
-MimpairedMgasMexchange,Mhypercapnia
-Mhypoxemia-
MS3MheartMsound,MshortnessMofMbreath,Mcrackles,MpinkyMfrothyMsputum,Manxiety
CausesMofMcardiogenicMpulmonaryMedemaM-
MAnswerMmyocardialMinfarction,MheartMfailure,MhypertensiveMcrisis,MmitralMregurgitation,M
tamponade
,TreatmentMofMpulmonaryMedemaM-MAnswerM-decreaseMpreload
-loopMdiuretics
-nitroglycerin
-morphine
-MCPAPMorMBIPAP
-MPositiveMinotropeMtoMimproveMcontractility
CardiacMoutputM(CO)M-MAnswerM4-8ML/min
CardiacMindexM(CI)M-MAnswerM2.5-4ML/min/m2
StrokeMvolumeM(SV)M-MAnswerM50-100Mml/beat
StrokeMvolumeMindexM-MAnswerM35-60Mml/beat/m2
RightMventricularMstrokeMworkMindexM(RVSWI)M-MAnswerM5-10Mg/m2/beat
LeftMventricularMstrokeMworkMindexM(LVSWI)M-MAnswerM50-62Mg/m2/beat
SVO2M-MAnswerM60-75%
Scvo2M-MAnswerMoverM70%M(70-85%)
pulmonaryMarteryMpressureM-MAnswerM25/10MmmHG
PAOPM-MAnswerM8-12MmmHG
RAP/CVPM-MAnswerM2-8MmmHG
SVRM-MAnswerM900-1400Mdynes/sec/cm-5
, SVRIM-MAnswerM1970-2390Mdynes/sec/cm-5/m2
PVRM-MAnswerM90-250MDynes/sec/cm-5
LVMpressureM-MAnswerM100Mmmhg
CardiacMoutputMformulaM-MAnswerMCO=SVxHR
MAP=M-MAnswerMCOMxMSVR
CardiacMoutputMcanMbeMmeasuresMwithM-
MAnswerMPulmonaryMarteryMcatheter,Mechocardiogram,MindirectlyMviaMfunctionalMhemody
namics,MnoninvasiveMmethodsM(bioreactanceMandMcontinuousMdigitMCO),MfickMequation
inMlowMoutputMstatesMpatientsMcompensateMwithM-
MAnswerMtachycardia,MCOMmayMbeMnormalMwhenMtheMpatientMisMtachycardicMwithMlo
werMSV
StrokeMvolumeMformulaM-MAnswerMSV=MendMdiastolicMvolume-MendMsystolicMvolumeM
SV=EDV-ESV
TypicalMEDVM-MAnswerM120Mml
amountMofMbloodMinMtheMheartMatMtheMendMofMdiastole
TypicalMESVM-MAnswerM50Mml
amountMofMbloodMinMtheMventriclesMatMendMofMejection/systole
ThreeMmeasuresMthatMcontributeMtoMstrokeMvolumeM-
MAnswerMcontractility,Mpreload,Mafterload
PreloadM-MAnswerMmyocardialMfiberMlengthMatMtheMendMofMdiastoleM-
stretchingMofMcardiacMmyocytesMpriorMtoMejection