AAB MT Hematology EXAM |\ |\ |\ |\
QUESTIONS WITH ANSWERS |\ |\
What is hemoglobin composed of?
|\ |\ |\ |\
A. 4 heme, 4 iron, 4 globins
|\ |\ |\ |\ |\ |\
B. 4 heme, 4 iron, 1 globin
|\ |\ |\ |\ |\ |\ |\
C. 2 heme, 2 iron, 2 globins
|\ |\ |\ |\ |\ |\
D. 1 heme, 1 iron, 1 globin - CORRECT ANSWERS ✅✅A. 4
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
heme, 4 iron, 4 globins
|\ |\ |\ |\ |\
What disorder does a defect in heme synthesis lead to?
|\ |\ |\ |\ |\ |\ |\ |\ |\
A. hemoglobinopathy
|\ |\
B. coagulopathy
|\ |\
C. thalassemia
|\
D. porphyria - CORRECT ANSWERS ✅✅D. porphyria
|\ |\ |\ |\ |\ |\
What is the function of the enzyme methemoglobin-
|\ |\ |\ |\ |\ |\ |\
cytochrome C reductase in red blood cell? |\ |\ |\ |\ |\ |\
,A. to keep iron in the ferric state
|\ |\ |\ |\ |\ |\ |\ |\
B. to keep iron in the ferrous state
|\ |\ |\ |\ |\ |\ |\ |\
C. to maintain an anaerobic pathway for glycolysis
|\ |\ |\ |\ |\ |\ |\
D. to maintain an aerobic pathway for the Krebs cycle -
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
CORRECT ANSWERS ✅✅B. to keep iron in the ferrous
|\ |\ |\ |\ |\ |\ |\ |\ |\
state
Which hemoglobin has a 200 times greater binding
|\ |\ |\ |\ |\ |\ |\ |\
capacity for the hemoglobin molecule than oxygen?
|\ |\ |\ |\ |\ |\
A. carboxyhemoglobin
|\
B. oxyhemoglobin
|\ |\
C. sulfhemoglobin
|\ |\
D. methemoglobin - CORRECT ANSWERS ✅✅A.
|\ |\ |\ |\ |\ |\
carboxyhemoglobin
What product is formed when ferrous iron of hemoglobin
|\ |\ |\ |\ |\ |\ |\ |\ |\
is oxidized to the ferric state?
|\ |\ |\ |\ |\
A. sulfhemoglobin
|\ |\
B. methemoglobin
|\
C. carboxyhemoglobin
|\ |\
D. cyanmethemoglobin - CORRECT ANSWERS ✅✅B.
|\ |\ |\ |\ |\ |\
methemoglobin
,Which hemoglobin derivative causes irreversible changes
|\ |\ |\ |\ |\ |\
in the red blood cells?
|\ |\ |\ |\
A. sulfhemoglobin
|\ |\
B. methemoglobin
|\
C. carboxyhemoglobin
|\ |\
D. cyanmethemoglobin - CORRECT ANSWERS ✅✅A.
|\ |\ |\ |\ |\ |\
sulfhemoglobin
Which of the following hemoglobin is NOT normally
|\ |\ |\ |\ |\ |\ |\ |\
present in a normal adult?
|\ |\ |\ |\
A. Hb-A1
|\
B. Hb-A
|\
C. Hb-S
|\
D. Hb-F - CORRECT ANSWERS ✅✅C. Hb-S
|\ |\ |\ |\ |\ |\
Which embryonic hemoglobin is normally found in
|\ |\ |\ |\ |\ |\ |\
newborns?
A. Hb-F
|\
B. Hb-Gower1
|\
, C. Hb-Gower2
|\
D. Hb-Portland - CORRECT ANSWERS ✅✅A. Hb-F
|\ |\ |\ |\ |\ |\
What is the most abundant hemoglobin in a newborn?
|\ |\ |\ |\ |\ |\ |\ |\
A. Hb-Gower
|\
B. Hb-A1
|\
C. Hb-A2
|\
D. Hb-F - CORRECT ANSWERS ✅✅D. Hb-F
|\ |\ |\ |\ |\ |\
What is the molecular structure of hemoglobin S?
|\ |\ |\ |\ |\ |\ |\
A. valine replaces glutamic acid in the 6th position of the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
beta chain
|\
B. lysine replaces glutamic acid in the 6th position of the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
beta chain
|\
C. lysine replaces glutamine in the 26th position of the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
beta chain
|\
D. valine replaces glutamine in the 26th position of the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
beta chain - CORRECT ANSWERS ✅✅A. valine replaces
|\ |\ |\ |\ |\ |\ |\ |\
glutamic acid in the 6th position of the beta chain
|\ |\ |\ |\ |\ |\ |\ |\ |\
Which of the following hemoglobin is insoluble under
|\ |\ |\ |\ |\ |\ |\ |\
lowered oxygen tension? |\ |\
QUESTIONS WITH ANSWERS |\ |\
What is hemoglobin composed of?
|\ |\ |\ |\
A. 4 heme, 4 iron, 4 globins
|\ |\ |\ |\ |\ |\
B. 4 heme, 4 iron, 1 globin
|\ |\ |\ |\ |\ |\ |\
C. 2 heme, 2 iron, 2 globins
|\ |\ |\ |\ |\ |\
D. 1 heme, 1 iron, 1 globin - CORRECT ANSWERS ✅✅A. 4
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
heme, 4 iron, 4 globins
|\ |\ |\ |\ |\
What disorder does a defect in heme synthesis lead to?
|\ |\ |\ |\ |\ |\ |\ |\ |\
A. hemoglobinopathy
|\ |\
B. coagulopathy
|\ |\
C. thalassemia
|\
D. porphyria - CORRECT ANSWERS ✅✅D. porphyria
|\ |\ |\ |\ |\ |\
What is the function of the enzyme methemoglobin-
|\ |\ |\ |\ |\ |\ |\
cytochrome C reductase in red blood cell? |\ |\ |\ |\ |\ |\
,A. to keep iron in the ferric state
|\ |\ |\ |\ |\ |\ |\ |\
B. to keep iron in the ferrous state
|\ |\ |\ |\ |\ |\ |\ |\
C. to maintain an anaerobic pathway for glycolysis
|\ |\ |\ |\ |\ |\ |\
D. to maintain an aerobic pathway for the Krebs cycle -
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
CORRECT ANSWERS ✅✅B. to keep iron in the ferrous
|\ |\ |\ |\ |\ |\ |\ |\ |\
state
Which hemoglobin has a 200 times greater binding
|\ |\ |\ |\ |\ |\ |\ |\
capacity for the hemoglobin molecule than oxygen?
|\ |\ |\ |\ |\ |\
A. carboxyhemoglobin
|\
B. oxyhemoglobin
|\ |\
C. sulfhemoglobin
|\ |\
D. methemoglobin - CORRECT ANSWERS ✅✅A.
|\ |\ |\ |\ |\ |\
carboxyhemoglobin
What product is formed when ferrous iron of hemoglobin
|\ |\ |\ |\ |\ |\ |\ |\ |\
is oxidized to the ferric state?
|\ |\ |\ |\ |\
A. sulfhemoglobin
|\ |\
B. methemoglobin
|\
C. carboxyhemoglobin
|\ |\
D. cyanmethemoglobin - CORRECT ANSWERS ✅✅B.
|\ |\ |\ |\ |\ |\
methemoglobin
,Which hemoglobin derivative causes irreversible changes
|\ |\ |\ |\ |\ |\
in the red blood cells?
|\ |\ |\ |\
A. sulfhemoglobin
|\ |\
B. methemoglobin
|\
C. carboxyhemoglobin
|\ |\
D. cyanmethemoglobin - CORRECT ANSWERS ✅✅A.
|\ |\ |\ |\ |\ |\
sulfhemoglobin
Which of the following hemoglobin is NOT normally
|\ |\ |\ |\ |\ |\ |\ |\
present in a normal adult?
|\ |\ |\ |\
A. Hb-A1
|\
B. Hb-A
|\
C. Hb-S
|\
D. Hb-F - CORRECT ANSWERS ✅✅C. Hb-S
|\ |\ |\ |\ |\ |\
Which embryonic hemoglobin is normally found in
|\ |\ |\ |\ |\ |\ |\
newborns?
A. Hb-F
|\
B. Hb-Gower1
|\
, C. Hb-Gower2
|\
D. Hb-Portland - CORRECT ANSWERS ✅✅A. Hb-F
|\ |\ |\ |\ |\ |\
What is the most abundant hemoglobin in a newborn?
|\ |\ |\ |\ |\ |\ |\ |\
A. Hb-Gower
|\
B. Hb-A1
|\
C. Hb-A2
|\
D. Hb-F - CORRECT ANSWERS ✅✅D. Hb-F
|\ |\ |\ |\ |\ |\
What is the molecular structure of hemoglobin S?
|\ |\ |\ |\ |\ |\ |\
A. valine replaces glutamic acid in the 6th position of the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
beta chain
|\
B. lysine replaces glutamic acid in the 6th position of the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
beta chain
|\
C. lysine replaces glutamine in the 26th position of the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
beta chain
|\
D. valine replaces glutamine in the 26th position of the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
beta chain - CORRECT ANSWERS ✅✅A. valine replaces
|\ |\ |\ |\ |\ |\ |\ |\
glutamic acid in the 6th position of the beta chain
|\ |\ |\ |\ |\ |\ |\ |\ |\
Which of the following hemoglobin is insoluble under
|\ |\ |\ |\ |\ |\ |\ |\
lowered oxygen tension? |\ |\
