HYPOTHALAMUS TO PITUITARY AXIS
(HPA) AND THYROID CERTIFICATION
FINAL PAPER 2026 SOLVED QUESTIONS
AND ACCURATE ANSWERS GRADED A+
● What hormone does the hypothalamus secrete in the HPT axis?
Answer: Thyrotropin-releasing hormone (TRH).
● What is the role of ACTH in the HPA axis? Answer: ACTH
(Adrenocorticotropic hormone) stimulates the adrenal gland to secrete
cortisol.
● What condition is characterized by high cortisol levels? Answer:
Cushing's disease.
● What are common symptoms of Cushing's disease? Answer: Weight
gain, a moon face, and fatigue.
● What is Addison's disease? Answer: A condition where cortisol levels
are too low, requiring hormone replacement.
● What happens to skin pigmentation in Addison's disease? Answer: The
skin gets darker.
(HPA) AND THYROID CERTIFICATION
FINAL PAPER 2026 SOLVED QUESTIONS
AND ACCURATE ANSWERS GRADED A+
● What hormone does the hypothalamus secrete in the HPT axis?
Answer: Thyrotropin-releasing hormone (TRH).
● What is the role of ACTH in the HPA axis? Answer: ACTH
(Adrenocorticotropic hormone) stimulates the adrenal gland to secrete
cortisol.
● What condition is characterized by high cortisol levels? Answer:
Cushing's disease.
● What are common symptoms of Cushing's disease? Answer: Weight
gain, a moon face, and fatigue.
● What is Addison's disease? Answer: A condition where cortisol levels
are too low, requiring hormone replacement.
● What happens to skin pigmentation in Addison's disease? Answer: The
skin gets darker.
