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Patho Exam 5 - Module 10: Hematology
Verified and Updated Questions and
Answers (100% Correct Answers)
Plasma proteins are ___% of the total plasma weight
Answer: 7% of the total plasma weight
What is the most abundant protein in the blood?
Answer: Albumin (approximately 60% of total plasma proteins, most abundant
protein in the blood)
- Function as carriers
- Plasma oncotic pressure
Globulins
Answer: Carrier proteins, carry ADEK vitamins, iron, lipids
Fibrinogen
Answer: - Least abundant protein in the blood
- Essential for blood clotting
Transferrin
Answer: - Major iron transport protein
- Transfers iron in circulation
- Precursor apotransferrin
- iron is a heavy metal, and since it is so, it is toxic unless it's bound to a protein
Ferritin
Answer: - Major intracellular iron storage protein
- Precursor apoferritin (ferritin without iron)
Hematopoiesis
Answer: • The process of blood cell production
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- Liver and spleen of a fetus
- Only in bone marrow after birth
- Humans need 100 billion new blood cells per day
Hematopoiesis occurs in the ______ in infants --> adults, and in the ______ in a fetus
Answer: Hematopoiesis occurs in the bone marrow in infants --> adults, and in the
liver and spleen in a fetus
Two stages of Hematopoiesis
Answer: - Mitosis (proliferation)
- Maturation (differentiation)
Bone marrow
Answer: • Also called myeloid tissue
• Red and yellow bone marrow
- Gets yellow color from fat
• Adult active bone marrow
- Pelvic bones, vertebrae, cranium and mandible, sternum and ribs, humerus, and
femur
The Young and the Hematologic System
Answer: • Blood cell counts increase above adult levels at birth and decline
gradually during childhood
- High counts after the trauma of birth and cutting of umbilical cord
• Polycythemia of the Newborn
- The hypoxic intrauterine environment stimulates erythropoietin production
• During the neonatal period, the rate of erythrocyte destruction is greater than that
in later childhood and adulthood
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• A full-term and premature infants, the erythrocyte lifespan is 60 to 80 days and 20
to 30 days, respectively.
Nutritional Requirements for Erythropoiesis - Vitamin B12
Answer: -DNA synthesis, maturation of red blood cells, folate metabolism
-Intrinsic Factor needed to utilize dietary B12
Nutritional Requirements for Erythropoiesis - Folic Acid (Folate)
Answer: Promotes erythropoiesis
Nutritional Requirements for Erythropoiesis - Vitamin C
Answer: Helps with iron metabolism
Nutritional Requirements for Erythropoiesis - Vitamin B6 and E and pantothenic acid
Answer: Heme synthesis
Nutritional Requirements for Erythropoiesis - Riboflavin
Answer: Manages oxidative reactions in erythropoiesis
Nutritional Requirements for Erythropoiesis - Niacin
Answer: - needed for respirations in erythrocytes
- presence of niacin allows the erythrocyte to utilize part of the Krebs cycle for
carbohydrate metabolism
Nutritional Requirements for Erythropoiesis - Minerals
Answer: - Iron: Hemoglobin synthesis
- Copper: Required for mobilization of iron from tissues to plasma
Nutritional Requirements for Erythropoiesis - Proteins
Answer: - Structural support
- Synthesis of hemoglobin
Erythrocytes
Answer: • Most abundant cells of the blood
• Responsible for tissue oxygenation.
Patho Exam 5 - Module 10: Hematology
Verified and Updated Questions and
Answers (100% Correct Answers)
Plasma proteins are ___% of the total plasma weight
Answer: 7% of the total plasma weight
What is the most abundant protein in the blood?
Answer: Albumin (approximately 60% of total plasma proteins, most abundant
protein in the blood)
- Function as carriers
- Plasma oncotic pressure
Globulins
Answer: Carrier proteins, carry ADEK vitamins, iron, lipids
Fibrinogen
Answer: - Least abundant protein in the blood
- Essential for blood clotting
Transferrin
Answer: - Major iron transport protein
- Transfers iron in circulation
- Precursor apotransferrin
- iron is a heavy metal, and since it is so, it is toxic unless it's bound to a protein
Ferritin
Answer: - Major intracellular iron storage protein
- Precursor apoferritin (ferritin without iron)
Hematopoiesis
Answer: • The process of blood cell production
,Inquire through: | Professional | Confidential Support
- Liver and spleen of a fetus
- Only in bone marrow after birth
- Humans need 100 billion new blood cells per day
Hematopoiesis occurs in the ______ in infants --> adults, and in the ______ in a fetus
Answer: Hematopoiesis occurs in the bone marrow in infants --> adults, and in the
liver and spleen in a fetus
Two stages of Hematopoiesis
Answer: - Mitosis (proliferation)
- Maturation (differentiation)
Bone marrow
Answer: • Also called myeloid tissue
• Red and yellow bone marrow
- Gets yellow color from fat
• Adult active bone marrow
- Pelvic bones, vertebrae, cranium and mandible, sternum and ribs, humerus, and
femur
The Young and the Hematologic System
Answer: • Blood cell counts increase above adult levels at birth and decline
gradually during childhood
- High counts after the trauma of birth and cutting of umbilical cord
• Polycythemia of the Newborn
- The hypoxic intrauterine environment stimulates erythropoietin production
• During the neonatal period, the rate of erythrocyte destruction is greater than that
in later childhood and adulthood
, Inquire through: | Professional | Confidential Support
• A full-term and premature infants, the erythrocyte lifespan is 60 to 80 days and 20
to 30 days, respectively.
Nutritional Requirements for Erythropoiesis - Vitamin B12
Answer: -DNA synthesis, maturation of red blood cells, folate metabolism
-Intrinsic Factor needed to utilize dietary B12
Nutritional Requirements for Erythropoiesis - Folic Acid (Folate)
Answer: Promotes erythropoiesis
Nutritional Requirements for Erythropoiesis - Vitamin C
Answer: Helps with iron metabolism
Nutritional Requirements for Erythropoiesis - Vitamin B6 and E and pantothenic acid
Answer: Heme synthesis
Nutritional Requirements for Erythropoiesis - Riboflavin
Answer: Manages oxidative reactions in erythropoiesis
Nutritional Requirements for Erythropoiesis - Niacin
Answer: - needed for respirations in erythrocytes
- presence of niacin allows the erythrocyte to utilize part of the Krebs cycle for
carbohydrate metabolism
Nutritional Requirements for Erythropoiesis - Minerals
Answer: - Iron: Hemoglobin synthesis
- Copper: Required for mobilization of iron from tissues to plasma
Nutritional Requirements for Erythropoiesis - Proteins
Answer: - Structural support
- Synthesis of hemoglobin
Erythrocytes
Answer: • Most abundant cells of the blood
• Responsible for tissue oxygenation.
