Inquire through: | Professional | Confidential Support
Pharm Final - Module 13: Pain, Gout Verified
and Updated Questions and Answers (100%
Correct Answers)
What are some examples of NSAIDs?
Answer: • Ibuprofen
• Naproxen
• Diflofenac- topical and oral
• Celecoxib
• Meloxicam
• Ketoralac - IM and PO
What is a primary difference between a NSAID and acetaminophen?
Answer: • NSAIDs work well for inflammatory pain, whereas there is limited efficacy
for inflammation
What is the black box warning for a NSAID?
Answer: • CV/GI/Renal/Bleeding
What are some potential adverse effects of NSAIDs? Acetaminophen?
Answer: • NSAIDS: GI bleeds (consider PPI as well if long term use), renal toxicity
(avoid in CrCl <60), can alter antiplatelet effects of aspirin (take 2 hrs apart), increase
BP, not recommended in pregnancy
• Acetaminophen: hepatoxicity, CV disease, renal failure
What should be routinely monitored if a patient has been taking a NSAID for an
extended period of time?
Answer: • Kidney function
Which OTC analgesic is safer for a patient with CKD who has acute pain?
Answer: • Acetaminophen
• Topical NSAID
, Inquire through: | Professional | Confidential Support
• Duloxetine
What are some examples of a muscle relaxant and when might it be considered?
Answer: • Examples: Cyclobenzaprine
• Indications: acute pain, like low back pain
• Can cause sedation/anticholinergic effects
Which drugs might be used to treat neuropathic pain?
Answer: • SNRIs (duloxetine)
• TCAs (amitriptyline)
• Antiepileptics: gabapentin, pregabalin
What pharmacologic agents may be helpful in the treatment of fibromyalgia?
Answer: • Duloxetine
• Gabapentin
• Pregabalin
• Milnacipran
• Amitriptyline (no FDA approval for fibromyalgia, but has been used successfully in
practice)
• Cyclobenzaprine (no FDA approval for fibromyalgia, but has been used successfully
in practice)
What are some primary pharmacologic considerations for the different types of pain
(ex: nociceptive, neuropathic, central)?
Answer: • Nociceptive: adaptive/protective, sharp, dull, throbbing, aching
• Inflammatory: adaptive/protective, might throb or ache, sometimes considered a
subcategory of nociceptive pain
• Neuropathic: maladaptive, hypersensitivity, may feel electric, burning, pins and
needles, tingling, shooting
Pharm Final - Module 13: Pain, Gout Verified
and Updated Questions and Answers (100%
Correct Answers)
What are some examples of NSAIDs?
Answer: • Ibuprofen
• Naproxen
• Diflofenac- topical and oral
• Celecoxib
• Meloxicam
• Ketoralac - IM and PO
What is a primary difference between a NSAID and acetaminophen?
Answer: • NSAIDs work well for inflammatory pain, whereas there is limited efficacy
for inflammation
What is the black box warning for a NSAID?
Answer: • CV/GI/Renal/Bleeding
What are some potential adverse effects of NSAIDs? Acetaminophen?
Answer: • NSAIDS: GI bleeds (consider PPI as well if long term use), renal toxicity
(avoid in CrCl <60), can alter antiplatelet effects of aspirin (take 2 hrs apart), increase
BP, not recommended in pregnancy
• Acetaminophen: hepatoxicity, CV disease, renal failure
What should be routinely monitored if a patient has been taking a NSAID for an
extended period of time?
Answer: • Kidney function
Which OTC analgesic is safer for a patient with CKD who has acute pain?
Answer: • Acetaminophen
• Topical NSAID
, Inquire through: | Professional | Confidential Support
• Duloxetine
What are some examples of a muscle relaxant and when might it be considered?
Answer: • Examples: Cyclobenzaprine
• Indications: acute pain, like low back pain
• Can cause sedation/anticholinergic effects
Which drugs might be used to treat neuropathic pain?
Answer: • SNRIs (duloxetine)
• TCAs (amitriptyline)
• Antiepileptics: gabapentin, pregabalin
What pharmacologic agents may be helpful in the treatment of fibromyalgia?
Answer: • Duloxetine
• Gabapentin
• Pregabalin
• Milnacipran
• Amitriptyline (no FDA approval for fibromyalgia, but has been used successfully in
practice)
• Cyclobenzaprine (no FDA approval for fibromyalgia, but has been used successfully
in practice)
What are some primary pharmacologic considerations for the different types of pain
(ex: nociceptive, neuropathic, central)?
Answer: • Nociceptive: adaptive/protective, sharp, dull, throbbing, aching
• Inflammatory: adaptive/protective, might throb or ache, sometimes considered a
subcategory of nociceptive pain
• Neuropathic: maladaptive, hypersensitivity, may feel electric, burning, pins and
needles, tingling, shooting
