Inquire through: | Professional | Confidential Support
Pharm Quiz 3 - GI & Male GU Verified and
Updated Questions and Answers (100%
Correct Answers)
Cimetidine (Tagamet)
Answer: • Antiacid/antihistamine
• Different pharmacokinetics from other agents
• Greater propensity to inhibit the metabolism of the P-450 cytochrome enzyme
system, therefore decreasing their clearance and enhancing the effects of other drugs
when administered concurrently.
• Dermatologists have suggested hi -dose cimetidine tid or qid for children to help
get rid of warts.
- It takes 2 to 3 months to see an improvement
Famotidine (Pepcid)
Answer: H2 Receptor Antagonist
Omeprazole (Prilosec)
Answer: • PPI
• Omeprazole chewable tablets should be taken once daily on an empty stomach, 1
hour prior to meals
• Dose for 4-8 weeks once a day, needs to be given an hour before meals
Pantoprazole (Protonix)
Answer: • PPI
• The only PPI on the TennCare PDL
• False-positive urine screening tests for tetrahydrocannabinol (THC)
Esomeprazole (Nexium)
Answer: • PPI
, Inquire through: | Professional | Confidential Support
• S-Isomer of omeprazole, metabolized slower than omeprazole
• For GERD take for 4-8 weeks
• For PUD take for 2 weeks - 6 months
• Most effective for GERD and PUD (before Zegrid was on the market)
Metoclopramide (reglan)
Answer: • MOA: increase esophageal motility and gastric emptying rate and perhaps
some effects to increase LES resting pressure
• 12 weeks maximum
• Give doses 30 min prior to meals
• SE: May cause dystonic (extrapyramidal or EPS) or tardive dyskinesia (TD) reactions,
can increase suicidality, more likely to have HTN crisis when taking with MAOI,
additive sedation with EtOH and Benzos
• Other indications: diabetic gastroparesis and an anti-emetic in cancer
chemotherapy.
Ondansetron (Zofran)
Answer: • Serotonin Antagonist
• MOA: work centrally in the chemoreceptor trigger zone and also peripherally in the
upper GI tract
• SE: constipation, headache, fatigue
Promethazine (Phenergan)
Answer: • MOA: involves dopamine receptor blockade in the chemoreceptor trigger
zone
• Not be used age 2 years
• Pregnancy Category C
• Given orally, rectally, or parenterally.
Pharm Quiz 3 - GI & Male GU Verified and
Updated Questions and Answers (100%
Correct Answers)
Cimetidine (Tagamet)
Answer: • Antiacid/antihistamine
• Different pharmacokinetics from other agents
• Greater propensity to inhibit the metabolism of the P-450 cytochrome enzyme
system, therefore decreasing their clearance and enhancing the effects of other drugs
when administered concurrently.
• Dermatologists have suggested hi -dose cimetidine tid or qid for children to help
get rid of warts.
- It takes 2 to 3 months to see an improvement
Famotidine (Pepcid)
Answer: H2 Receptor Antagonist
Omeprazole (Prilosec)
Answer: • PPI
• Omeprazole chewable tablets should be taken once daily on an empty stomach, 1
hour prior to meals
• Dose for 4-8 weeks once a day, needs to be given an hour before meals
Pantoprazole (Protonix)
Answer: • PPI
• The only PPI on the TennCare PDL
• False-positive urine screening tests for tetrahydrocannabinol (THC)
Esomeprazole (Nexium)
Answer: • PPI
, Inquire through: | Professional | Confidential Support
• S-Isomer of omeprazole, metabolized slower than omeprazole
• For GERD take for 4-8 weeks
• For PUD take for 2 weeks - 6 months
• Most effective for GERD and PUD (before Zegrid was on the market)
Metoclopramide (reglan)
Answer: • MOA: increase esophageal motility and gastric emptying rate and perhaps
some effects to increase LES resting pressure
• 12 weeks maximum
• Give doses 30 min prior to meals
• SE: May cause dystonic (extrapyramidal or EPS) or tardive dyskinesia (TD) reactions,
can increase suicidality, more likely to have HTN crisis when taking with MAOI,
additive sedation with EtOH and Benzos
• Other indications: diabetic gastroparesis and an anti-emetic in cancer
chemotherapy.
Ondansetron (Zofran)
Answer: • Serotonin Antagonist
• MOA: work centrally in the chemoreceptor trigger zone and also peripherally in the
upper GI tract
• SE: constipation, headache, fatigue
Promethazine (Phenergan)
Answer: • MOA: involves dopamine receptor blockade in the chemoreceptor trigger
zone
• Not be used age 2 years
• Pregnancy Category C
• Given orally, rectally, or parenterally.
