Inquire through: | Professional | Confidential Support
Supplements and Hormones Verified and
Updated Questions and Answers (100%
Correct Answers)
Omega-3 Fatty Acids - Uses
Answer: · MDD: 1-2g/day of EPA are recommended for adjunctive use in MDD
· Bipolar disorder: mixed evidence for bipolar depression
· May consider doses up to 4g/day with increased inflammation
Omega-3 Fatty Acids: be cautious of use with
Answer: anticoagulants
Omega-3 Fatty Acids found in
Answer: fish, flax seed, kelp
Vitamin D - Uses:
Answer: · MDD: 1500 IU - 4000 IU/day weekly recommended for adjunctive
hormonotherapy use
· ADHD: 1500-4000 IU/day weakly recommended for adjunctive use in children
· Smaller daily or weekly doses preferred to bolus dose
Vitamin D - Dosing and Serum Levels
Answer: · Consider dosing based on serum Vitamin D, 25-Hydroxy
· Serum: 25-80 ng/mL (I consider optimal 50-80 ng/mL)
Vitamin D may be more beneficial
Answer: in winter months
Vitamin D_ is better absorbed than D_
Answer: Vitamin D3 is better absorbed than D2
Methylfolate Uses:
Answer: · MDD: 15mg/day may be used adjunctively; folic acid is not recommended
, Inquire through: | Professional | Confidential Support
· Schizophrenia: 1-15mg/day provisionally recommended for adjunctive treatment of
negative symptoms
Methylfolate may be beneficial in individuals with
Answer: increased inflammation, obesity, and preconception/pregnancy
Methylfolate - Safety Data
Answer: Adequate safety data, high doses linked with cancer
If _________ levels are elevated then consider adding methylfolate
Answer: If homocysteine levels are elevated then consider adding methylfolate
Probiotics
Answer: · Lactobacillus and Bifidobacterium spp. 1-10 billion units/day may be used
adjunctively for MDD
· These strains have been most widely studied
· Bacteria strain may depend on individual’s genetics, diet, and microbiome
· Robust safety data
Magnesium - Uses:
Answer: -MDD: CANMAT does not currently support use of doses of 100-400mg/day
not recommended for adjunctive or monotherapy; other reviews have supported its
use in the treatment of depression
-Insomnia: may improve initial insomnia and restless leg symptoms
Magnesium - Safety Data
Answer: -Robust safety data within therapeutic dose range
-High doses may impact absorption of other minerals
-May cause GI distress in higher doses
· May consider dosing based on lab values
Magnesium - Levels
Answer: -Serum: 1.6-2.6 mEq/L
Supplements and Hormones Verified and
Updated Questions and Answers (100%
Correct Answers)
Omega-3 Fatty Acids - Uses
Answer: · MDD: 1-2g/day of EPA are recommended for adjunctive use in MDD
· Bipolar disorder: mixed evidence for bipolar depression
· May consider doses up to 4g/day with increased inflammation
Omega-3 Fatty Acids: be cautious of use with
Answer: anticoagulants
Omega-3 Fatty Acids found in
Answer: fish, flax seed, kelp
Vitamin D - Uses:
Answer: · MDD: 1500 IU - 4000 IU/day weekly recommended for adjunctive
hormonotherapy use
· ADHD: 1500-4000 IU/day weakly recommended for adjunctive use in children
· Smaller daily or weekly doses preferred to bolus dose
Vitamin D - Dosing and Serum Levels
Answer: · Consider dosing based on serum Vitamin D, 25-Hydroxy
· Serum: 25-80 ng/mL (I consider optimal 50-80 ng/mL)
Vitamin D may be more beneficial
Answer: in winter months
Vitamin D_ is better absorbed than D_
Answer: Vitamin D3 is better absorbed than D2
Methylfolate Uses:
Answer: · MDD: 15mg/day may be used adjunctively; folic acid is not recommended
, Inquire through: | Professional | Confidential Support
· Schizophrenia: 1-15mg/day provisionally recommended for adjunctive treatment of
negative symptoms
Methylfolate may be beneficial in individuals with
Answer: increased inflammation, obesity, and preconception/pregnancy
Methylfolate - Safety Data
Answer: Adequate safety data, high doses linked with cancer
If _________ levels are elevated then consider adding methylfolate
Answer: If homocysteine levels are elevated then consider adding methylfolate
Probiotics
Answer: · Lactobacillus and Bifidobacterium spp. 1-10 billion units/day may be used
adjunctively for MDD
· These strains have been most widely studied
· Bacteria strain may depend on individual’s genetics, diet, and microbiome
· Robust safety data
Magnesium - Uses:
Answer: -MDD: CANMAT does not currently support use of doses of 100-400mg/day
not recommended for adjunctive or monotherapy; other reviews have supported its
use in the treatment of depression
-Insomnia: may improve initial insomnia and restless leg symptoms
Magnesium - Safety Data
Answer: -Robust safety data within therapeutic dose range
-High doses may impact absorption of other minerals
-May cause GI distress in higher doses
· May consider dosing based on lab values
Magnesium - Levels
Answer: -Serum: 1.6-2.6 mEq/L
