GUIDE 2026 FULLY SOLVED QUESTION SET
◉Griffith's Experiment (1928). Answer: reinforced that there is a
transforming principle. Experiments with virulent and avirulent
forms of pneumonia bacteria
◉Avery, MacLeod and McCarty's Experiment (1944). Answer: DNA
is the transforming principle. Biochemical experiments using R and
S cell extracts.
◉Astbury's Experiment (1947). Answer: DNA has a regular
structure
◉Chargaff's Experiment (1949). Answer: predictable proportions of
nucleotides... Chargaff's Rules
◉Hershey and Chase's Experiment (1952). Answer: DNA (not
protein!) directed the production of viral particles
◉Franklin's Experiment (1953). Answer: additional physical
characteristics of DNA molecule
, ◉Watson and Crick's Experiment (1953). Answer: put it all together
- Double helix!
◉Nucleotides. Answer: phosphate group, ribose sugar, nitrogenous
base
◉How are nucleotides joined?. Answer: They are joined by
phosphodiester linkages
◉polarity of DNA. Answer: 5' end (phosphate); 3' end (-OH)
◉DNA is double stranded. Answer: strands are held together by
hydrogen bonds
◉DNA is helical. Answer: strands run anti-parallel
◉DNA Replication - Conservative. Answer:
◉DNA Replication - Semi-Conservative. Answer:
◉DNA Replication - Dispersive. Answer: