NUR 529 EXAM 1 PRACTICE SOLUTION
SCRIPT 2026 VERIFIED 150 PLUS
QUESTIONS AND DETAILED ANSWERS
COMPLETE STUDY SHEET GRADED A+
⩥ Stages of Hemostasis. Answer: Vessel Spasm, formation of the
platelet plug, blood coagulation (clot retraction, clot dissolution)
⩥ Vessel Spasm. Answer: First stage of hemostasis, constricts the vessel
and reduces blood flow. It is a transient event that usually lasts minutes
or hours.
⩥ Formation of the platelet plug. Answer: Second stage of hemostasis, 1.
platelets are attracted to damaged vessel wall. 2. activation by sub-
endothelial tissue. 3. change from smooth disks to spiny spheres. 4.
exposing glycoprotein receptors on their surfaces. This step requires a
protein molecule called von Willebrand factor that leaks into the injured
tissue from the plasma. (adhesion, activation, aggregation)
⩥ During Hemostasis, platelets change from ...... Answer: Smooth disks
to spiny spheres
⩥ von Willebrand factor. Answer: Formation of the platelet plug requires
a protein molecule called (helps platelets stick together)
,⩥ Glycoprotein Receptors. Answer: Exposed during the formation of the
platelet plug when platelets change from smooth disks to spiny spheres
⩥ 1.Blood coagulation or development of an insoluble fibrin clot.
Answer: Third step of hemostasis: stabilization of the plug occurs as the
coagulation pathway is activated on the platelet surface, and fibrinogen
is converted to fibrin.
⩥ Thrombocytopenia. Answer: Results from a decrease in platelet
production, increased sequestration of platelets in the spleen, or
decreased platelet survival
⩥ Drug induced thrombocytopenia. Answer: can be from aspirin,
atorvastatin, antibiotics and of course Heparin.
⩥ Clot retraction. Answer: the consolidation or tightening of the fibrin
clot pulls the edges of the damaged vessel close together, allowing for
repair of the vessel lining.
⩥ Clot dissolution. Answer: fibrinolysis occurs through conversion of
plasminogen to plasmin by tissue plasminogen activator (tPA), which is
released from damaged endothelial cells. This conversion results in
digestion of fibrin fibers within the clot and the production of fibrin
degradation products.... Clot dissolves.
,⩥ Immune thrombocytopenia. Answer: was formally called idiopathic
thrombocytopenia purpura. ITP is the most common thrombocytopenic
disorder among children and often follows an upper respiratory
infection.
⩥ Thrombotic Thrombocytopenic. Answer: rare and caused by a
deficiency of the gene responsible for severing large von Willebrand
factor proteins. The unchecked platelet aggregation results in
microvascular occlusions...end organ failure
⩥ Spontaneous bleeding from platelet disorders. Answer: Most often
involves small vessels of mucous membranes and skin, common sites
are nose, mouth, GI, uterine
⩥ Cutaneous bleeding. Answer: seen as pinpoint hemorrhages
(petechiae), or purple areas of bruising (purpura)
⩥ Petechiae. Answer: Occur almost exclusively in conditions of platelet
deficiency, not dysfunction
⩥ 120 days. Answer: RBC lifespan
⩥ Spleen. Answer: Breaks down RBC
, ⩥ 5 years. Answer: Almost all bones produce RBCS to maintain growth
rate until this age
⩥ Red bone marrow. Answer: RBCS produced here after birth
⩥ 20 years. Answer: Age when red cell production takes place mainly in
the membranous bones of the vertebrae, sternum, ribs, and pelvis and
red marrow changes to fatty yellow due to decreased activity
⩥ Iron and amino acids. Answer: Degradation products recycled when
RBCS are broken down
⩥ Hematocrit. Answer: Measures the volume of red cell mass in 100 mL
of plasma volume
⩥ Transfusion reaction symptoms. Answer: •Sensation of heat along the
vein where the blood is being infused
•Flushing of the face
•Urticaria/rash, headache, pain in the lumbar area
•Chills, fever, constricting pain in the chest
•Cramping pain in the abdomen
•Nausea, vomiting
•Tachycardia, hypotension, and dyspnea
SCRIPT 2026 VERIFIED 150 PLUS
QUESTIONS AND DETAILED ANSWERS
COMPLETE STUDY SHEET GRADED A+
⩥ Stages of Hemostasis. Answer: Vessel Spasm, formation of the
platelet plug, blood coagulation (clot retraction, clot dissolution)
⩥ Vessel Spasm. Answer: First stage of hemostasis, constricts the vessel
and reduces blood flow. It is a transient event that usually lasts minutes
or hours.
⩥ Formation of the platelet plug. Answer: Second stage of hemostasis, 1.
platelets are attracted to damaged vessel wall. 2. activation by sub-
endothelial tissue. 3. change from smooth disks to spiny spheres. 4.
exposing glycoprotein receptors on their surfaces. This step requires a
protein molecule called von Willebrand factor that leaks into the injured
tissue from the plasma. (adhesion, activation, aggregation)
⩥ During Hemostasis, platelets change from ...... Answer: Smooth disks
to spiny spheres
⩥ von Willebrand factor. Answer: Formation of the platelet plug requires
a protein molecule called (helps platelets stick together)
,⩥ Glycoprotein Receptors. Answer: Exposed during the formation of the
platelet plug when platelets change from smooth disks to spiny spheres
⩥ 1.Blood coagulation or development of an insoluble fibrin clot.
Answer: Third step of hemostasis: stabilization of the plug occurs as the
coagulation pathway is activated on the platelet surface, and fibrinogen
is converted to fibrin.
⩥ Thrombocytopenia. Answer: Results from a decrease in platelet
production, increased sequestration of platelets in the spleen, or
decreased platelet survival
⩥ Drug induced thrombocytopenia. Answer: can be from aspirin,
atorvastatin, antibiotics and of course Heparin.
⩥ Clot retraction. Answer: the consolidation or tightening of the fibrin
clot pulls the edges of the damaged vessel close together, allowing for
repair of the vessel lining.
⩥ Clot dissolution. Answer: fibrinolysis occurs through conversion of
plasminogen to plasmin by tissue plasminogen activator (tPA), which is
released from damaged endothelial cells. This conversion results in
digestion of fibrin fibers within the clot and the production of fibrin
degradation products.... Clot dissolves.
,⩥ Immune thrombocytopenia. Answer: was formally called idiopathic
thrombocytopenia purpura. ITP is the most common thrombocytopenic
disorder among children and often follows an upper respiratory
infection.
⩥ Thrombotic Thrombocytopenic. Answer: rare and caused by a
deficiency of the gene responsible for severing large von Willebrand
factor proteins. The unchecked platelet aggregation results in
microvascular occlusions...end organ failure
⩥ Spontaneous bleeding from platelet disorders. Answer: Most often
involves small vessels of mucous membranes and skin, common sites
are nose, mouth, GI, uterine
⩥ Cutaneous bleeding. Answer: seen as pinpoint hemorrhages
(petechiae), or purple areas of bruising (purpura)
⩥ Petechiae. Answer: Occur almost exclusively in conditions of platelet
deficiency, not dysfunction
⩥ 120 days. Answer: RBC lifespan
⩥ Spleen. Answer: Breaks down RBC
, ⩥ 5 years. Answer: Almost all bones produce RBCS to maintain growth
rate until this age
⩥ Red bone marrow. Answer: RBCS produced here after birth
⩥ 20 years. Answer: Age when red cell production takes place mainly in
the membranous bones of the vertebrae, sternum, ribs, and pelvis and
red marrow changes to fatty yellow due to decreased activity
⩥ Iron and amino acids. Answer: Degradation products recycled when
RBCS are broken down
⩥ Hematocrit. Answer: Measures the volume of red cell mass in 100 mL
of plasma volume
⩥ Transfusion reaction symptoms. Answer: •Sensation of heat along the
vein where the blood is being infused
•Flushing of the face
•Urticaria/rash, headache, pain in the lumbar area
•Chills, fever, constricting pain in the chest
•Cramping pain in the abdomen
•Nausea, vomiting
•Tachycardia, hypotension, and dyspnea
