QUESTIONS WITH FULL SOLUTION
◉ Sickle Cell Anemia. Answer: Pathophysiology: Hypoxia occurs and
causes sickling
◉ Sickle Cell Anemia. Answer: No cure (except possibly bone
marrow transplants)
◉ Sickle Cell Anemia. Answer: Supportive care/prevent sickling
episodes
◉ Sickle Cell Anemia. Answer: Frequent bacterial infections may
occur because of immunocompromise
◉ Sickle Cell Anemia. Answer: Bacterial infection is leading cause of
death in young children
◉ Sickle Cell Anemia. Answer: Strokes in 5% to 10% of children
◉ Sickle Cell Crisis. Answer: Anything that increases body's need for
oxygen or alters transport of oxygen
, ◉ Sickle Cell Crisis. Answer: Trauma
◉ Sickle Cell Crisis. Answer: Infection, fever
◉ Sickle Cell Crisis. Answer: Physical and emotional stress
◉ Sickle Cell Crisis. Answer: Increased blood viscosity caused by
dehydration
◉ Sickle Cell Crisis. Answer: Hypoxia
◉ Sickle Cell Crisis. Answer: Acute exacerbations that vary in
severity and frequency
◉ Sickle Cell Crisis. Answer: Vaso-occlusive thrombotic
◉ Vaso-occlusive thrombotic. Answer: Most common type of sickle
cell crisis; very painful
◉ Vaso-occlusive thrombotic. Answer: Stasis of blood with clumping
of cells in microcirculation→ischemia→infarction