Distillation and Column Chromatography
1. column chromatography is a: purification technique used to isolate compounds from a mixture
2. Boiling point is the temperature at which: a liquid changes into vapor due to the fact that the
vapor pressure of the liquid equals the pressure surrounding the liquid
3. What does BP depend on?: intrinsic forces such as molecular weight , structure, intermolecular forces
4. Objective of this experiment: Separate and purify a mixture of essential oils, Purify a compound using
vacuum distillation, Purify a compound using vacuum flash chromatography, Identify unknowns based on GCMS
5. Distillation
is a purification method that allows : separation of a
liquid from a mixture based on the difference among the individual BP of the mixture components.
6. When setting up distillation experiments it is
important to remember the closer the BP, the is the path that the vapors have to
travel before they are collected upon condensation.: longer
7. What would happen if 400 mesh silica gel was used for a gravity column?: The
solvent will pass through the column too slowly.
8. Before running a column you
should .: Run a TLC to determine the correct mobile
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3
1. column chromatography is a: purification technique used to isolate compounds from a mixture
2. Boiling point is the temperature at which: a liquid changes into vapor due to the fact that the
vapor pressure of the liquid equals the pressure surrounding the liquid
3. What does BP depend on?: intrinsic forces such as molecular weight , structure, intermolecular forces
4. Objective of this experiment: Separate and purify a mixture of essential oils, Purify a compound using
vacuum distillation, Purify a compound using vacuum flash chromatography, Identify unknowns based on GCMS
5. Distillation
is a purification method that allows : separation of a
liquid from a mixture based on the difference among the individual BP of the mixture components.
6. When setting up distillation experiments it is
important to remember the closer the BP, the is the path that the vapors have to
travel before they are collected upon condensation.: longer
7. What would happen if 400 mesh silica gel was used for a gravity column?: The
solvent will pass through the column too slowly.
8. Before running a column you
should .: Run a TLC to determine the correct mobile
1/
3
