1|Page
NURS 6521 Advanced Pharmacology Final Exam
2026/2027 | Verified Questions & Answers with Detailed
Rationales | NGN-Aligned Grade A Study Guide
1. A 71-year-old man has just been prescribed finasteride (Proscar). Which of the
following complaints by this patient most likely indicated a need for this drug?
A. "I have been having difficulty sleeping at night."
B. "Lately, I have to get up three or four times a night to go to the bathroom."
C. "I have been experiencing frequent headaches in the morning."
D. "My blood pressure has been running high."
Correct Answer: B
Rationale: Finasteride is used to treat benign prostatic hyperplasia (BPH). Nocturia
(frequent nighttime urination) is a classic symptom of BPH indicating the need for this
medication.
,2|Page
2. After 6 months of unsuccessfully trying to conceive, a 31-year-old woman and her
husband have sought a referral to a fertility specialist in order to explore their options. A
nurse at the clinic should recognize that the woman may benefit from:
A. clomiphene
B. progesterone
C. estrogen
D. testosterone
Correct Answer: A
Rationale: Clomiphene is a selective estrogen receptor modulator used as first-line
therapy for ovulation induction in infertility due to anovulation.
3. Which of the following would the nurse include in a teaching plan about the signs and
symptoms of thrombophlebitis and thromboembolism that should be reported by a
patient taking estrogen?
A. Headaches and chest pain
B. Weight gain and bloating
C. Nausea and breast tenderness
D. Mood changes and irritability
Correct Answer: A
,3|Page
Rationale: Headaches (especially severe) and chest pain may indicate thromboembolic
events such as stroke or pulmonary embolism, which are serious adverse effects of
estrogen therapy requiring immediate reporting.
4. A 38-year-old pregnant patient admits to the nurse that she is an alcoholic and has
been consuming alcohol during her pregnancy. The nurse knows that using alcohol
during pregnancy may result in a child who presents with:
A. microcephaly
B. macrocephaly
C. hydrocephalus
D. anencephaly
Correct Answer: A
Rationale: Fetal alcohol syndrome causes microcephaly (small head circumference)
along with growth retardation, facial abnormalities, and neurodevelopmental deficits.
5. A nurse practitioner orders 150 mg of oral fluconazole for a patient with vulvovaginal
candidiasis. The patient should expect to take medication:
A. Once a day
B. Twice a day
, 4|Page
C. Three times a day
D. Four times a day
Correct Answer: A
Rationale: Fluconazole for uncomplicated vulvovaginal candidiasis is typically
administered as a single 150 mg oral dose.
6. An oncology nurse is reviewing the pathophysiology of cancer and is discussing with a
colleague the factors that contribute to the success or failure of a patient's
chemotherapy. Which of the following cancerous cells is most susceptible to the effects
of chemotherapeutic drugs?
A. Cells that have a rapid mitotic rate
B. Cells that have a slow mitotic rate
C. Cells that are in the G0 phase
D. Cells that are well-differentiated
Correct Answer: A
Rationale: Chemotherapeutic agents target rapidly dividing cells. Cancer cells with a
high mitotic rate are more susceptible to the effects of these drugs.
NURS 6521 Advanced Pharmacology Final Exam
2026/2027 | Verified Questions & Answers with Detailed
Rationales | NGN-Aligned Grade A Study Guide
1. A 71-year-old man has just been prescribed finasteride (Proscar). Which of the
following complaints by this patient most likely indicated a need for this drug?
A. "I have been having difficulty sleeping at night."
B. "Lately, I have to get up three or four times a night to go to the bathroom."
C. "I have been experiencing frequent headaches in the morning."
D. "My blood pressure has been running high."
Correct Answer: B
Rationale: Finasteride is used to treat benign prostatic hyperplasia (BPH). Nocturia
(frequent nighttime urination) is a classic symptom of BPH indicating the need for this
medication.
,2|Page
2. After 6 months of unsuccessfully trying to conceive, a 31-year-old woman and her
husband have sought a referral to a fertility specialist in order to explore their options. A
nurse at the clinic should recognize that the woman may benefit from:
A. clomiphene
B. progesterone
C. estrogen
D. testosterone
Correct Answer: A
Rationale: Clomiphene is a selective estrogen receptor modulator used as first-line
therapy for ovulation induction in infertility due to anovulation.
3. Which of the following would the nurse include in a teaching plan about the signs and
symptoms of thrombophlebitis and thromboembolism that should be reported by a
patient taking estrogen?
A. Headaches and chest pain
B. Weight gain and bloating
C. Nausea and breast tenderness
D. Mood changes and irritability
Correct Answer: A
,3|Page
Rationale: Headaches (especially severe) and chest pain may indicate thromboembolic
events such as stroke or pulmonary embolism, which are serious adverse effects of
estrogen therapy requiring immediate reporting.
4. A 38-year-old pregnant patient admits to the nurse that she is an alcoholic and has
been consuming alcohol during her pregnancy. The nurse knows that using alcohol
during pregnancy may result in a child who presents with:
A. microcephaly
B. macrocephaly
C. hydrocephalus
D. anencephaly
Correct Answer: A
Rationale: Fetal alcohol syndrome causes microcephaly (small head circumference)
along with growth retardation, facial abnormalities, and neurodevelopmental deficits.
5. A nurse practitioner orders 150 mg of oral fluconazole for a patient with vulvovaginal
candidiasis. The patient should expect to take medication:
A. Once a day
B. Twice a day
, 4|Page
C. Three times a day
D. Four times a day
Correct Answer: A
Rationale: Fluconazole for uncomplicated vulvovaginal candidiasis is typically
administered as a single 150 mg oral dose.
6. An oncology nurse is reviewing the pathophysiology of cancer and is discussing with a
colleague the factors that contribute to the success or failure of a patient's
chemotherapy. Which of the following cancerous cells is most susceptible to the effects
of chemotherapeutic drugs?
A. Cells that have a rapid mitotic rate
B. Cells that have a slow mitotic rate
C. Cells that are in the G0 phase
D. Cells that are well-differentiated
Correct Answer: A
Rationale: Chemotherapeutic agents target rapidly dividing cells. Cancer cells with a
high mitotic rate are more susceptible to the effects of these drugs.
